Biophysical Society 67th Annual Meeting Program Guide

427-pos Board B248 THE MEMBRANE PHASE TRANSITION DRIVES TUNABLE ASSEMBLY AND FUNCTION OF B CELL RECEPTOR SIGNALING DOMAINS. Sarah A. Shelby , Ivan Castello Serrano, Ilya Levental, Sarah L. Veatch 428-pos Board B249 THE INTERDEPENDENCE OF THERMODYNAMIC, MECHANICAL, AND STRUCTURAL PROPERTIES IN SATURATED PHOSPHOLIPID MEM BRANES. Nicholas B. Morris , Teshani Kumarage, Rana Ashkar 429-pos Board B250 ACCURATE ESTIMATION OF FREE ENERGY LANDSCAPE OF PHASE SEPARA TION IN LIPID BILAYERS. Ashlin James Poruthoor , Alan Grossfield 430-pos Board B251 CURVATURE INDUCED MEMBRANE STRUCTURE FROM FLUORES CENCE. Luis M. Davila Munoz , Radha Ranganathan 431-pos Board B252 PULMONARY SURFACTANT STRUCTURE AS SOLVED BY NEUTRON REFLEC TOMETRY AND ATOMIC FORCE MICROSCOPY. Ainhoa Collada , Armando Maestro, Johann Mertens, Emma Batllori-Badia, Alberto Galindo, Jesus Perez-Gil, Antonio Cruz Mechanosensation (Boards B253 - B281) 432-pos Board B253 MOUSE NODAL IMMOTILE CILIA SENSE BENDING DIRECTION FOR LEFT RIGHT DETERMINATION: MECHANICAL REGULATION IN INITIATION OF SYMMETRY BREAKING. Takanobu A. Katoh , Toshihiro Omori, Katsutoshi Mizuno, Takeshi Itabashi, Atsuko H. Iwane, Takuji Ishikawa, Yasushi Okada, Takayuki Nishizaka, Hiroshi Hamada 433-pos Board B254 SYNERGISTIC NANOMAGNETIC FORCES AND ARIPIPRAZOLE POTENTIATE GUIDED NEURITE OUTGROWTH. Madeline Conrad , Mackenna K. Landis, Anja Kunze 434-pos Board B255 TENSION-SUPPRESSED DEGRADATION OF COLLAGEN CONTROLS TISSUE STIFFNESS SCALING WITH FIBRILLAR COLLAGEN. Karanvir Saini , Sangkyun Cho, Manu Tewari, Abdelaziz Jalil, Mai Wang, Manasvita Vashisth, Alex Kasznel, Kazuhiro Yamamoto, David M. Chenoweth, Dennis E. Discher 435-pos Board B256 SUBSTRATE STIFFNESS INDUCES A CHRONIC ADAPTATION IN CONTRAC TILE WORK AND ELECTROPHYSIOLOGY OF CARDIOMYOCYTES. Pouria Tirgar , José Miguel Romero Sepúlveda, Cameron Hastie, Yuanyuan Tao, Gil Bub, Allen J. Ehrlicher 436-pos Board B257 GENETIC KNOCKOUT OF PRESTIN LIMITS CARDIAC HYPERTROPHY IN A MURINE PRESSURE OVERLOAD MODEL. Phung N. Thai , Lu Ren, Yankun Lyu, Daphne A. Diloretto, Valeriy Timofeyev, Ebenezer N. Yamoah, Xiao Dong Zhang, Nipavan Chiamvimonvat 437-pos Board B258 FUNCTIONAL SPECIALIZATIONS OF DROSOPHILA PRIMARY MECHANO SENSORY NEURONS. Stephen L. Holtz , Rachel I. Wilson 438-pos Board B259 NONLINEAR DYNAMICS OF SOUND DETECTION IN THE AMPHIBIAN AUDI TORY SYSTEM. Dzmitry Vaido , Martín A. Toderi, Dolores Bozovic 439-pos Board B260 USING LIGHT TO STUDY SOUND: STIMULATING HAIR CELLS WITH PHO TONIC PRESSURE. Sanjeewa Abeytunge, Francesco Gianoli, A. James Hudspeth, Andriy Kozlov

440-pos Board B261 DIFFERENTIAL NUCLEAR TRANSLOCATION OF STAT6 REGULATES THE MECHANOSENSITIVE IMMUNE CELL ACTIVATION. Dong-Hwee Kim 441-pos Board B262 FAT-FILLED LIPID DROPLETS WITH HIGH CURVATURE ACT AS STIFF INCLUSIONS THAT DISRUPT THE LAMINA, RUPTURE THE NUCLEUS AND INCREASE DNA DAMAGE. Irena L. Ivanovska , Michael P. Tobin, Lawrence J. Dooling, Dennis E. Discher 442-pos Board B263 NUCLEAR STIFFNESS REGULATES CELLULAR SENESCENCE VIA YAP DE PENDENT MECHANOTRANSDUCTION. Luv Kishore Srivastava , Ajinkya Ghagre, Allen J. Ehrlicher 443-pos Board B264 HYPERCONTRACTILITY BY HYPERTROPHIC CARDIOMYOPATHY MUTANT IPSC-CMS INDUCES HIPPO-YAP ACTIVATION THROUGH ENHANCED NUCLEAR DEFORMATION. Orlando N. Chirikian 444-pos Board B265 Travel Award Winner MITOCHONDRIAL FUNCTION IS REGULATED BY MECHANOSENSITIVE CHANNELS IN TRYPANOSOMA BRUCEI . Melvin Williams, Elissa Moller, Tiffine Pham, Sergei I. Sukharev, Veronica Jimenez 445-pos Board B266 BACTERIA BIOLUMINESCE IN RESPONSE TO FLUID SHEAR. Sumit Kumar Birwa , Raymond E. Goldstein, Nuno M. Oliveira 446-pos Board B267 THE ROLE OF PROTEIN-MEMBRANE ELECTROSTATIC INTERACTIONS IN THE ADAPTIVE GATING CYCLE OF MSCS. Madolyn Britt, Elissa Moller, Andriy Anishkin, Sergei I. Sukharev 447-pos Board B268 QUANTIFYING PRESSURE AND ULTRASOUND ACTIVATION OF THE MECH ANOSENSITIVE K + CHANNEL TRAAK. Trevor Docter , Ben Sorum, Robert A. RIetmeijer, Steve Brohawn 448-pos Board B269 THE ENERGETICS OF RAPID CELLULAR MECHANOTRANSDUCTION. Mi chael N. Young, Michael J. Sindoni, Amanda H. Lewis, Stefan Zauscher, Jörg M. Grandl 449-pos Board B270 DIRECT OBSERVATION OF PIEZO1 CONFORMATIONAL STATES. Eric M. Mulhall , Rachel Lee, Adrienne E. Dubin, Jesse Aaron, Michael Reiche, Anant Gharpure, Kara Marshall, Kathryn Spencer, Scott C. Henderson, Teng-Leong Chew, Ardem Patapoutian 450-pos Board B271 SINGLE-PARTICLE TRACKING AND MACHINE-LEARNING CLASSIFICATION REVEALS HETEROGENEOUS PIEZO1 DIFFUSION. Alan T. Ly , Vivek Tyagi, Gabriella A. Bertaccini, Elizabeth Evans, J. Alfredo Freites, Douglas J. Tobias, Medha M. Pathak 451-pos Board B272 Travel Award Winner VISUALIZATION OF MECHANICAL FORCES IN 3D CELL MODELS WITH MOLECULAR DNA TENSION PROBE. Qian Tian , Feiyu Yang, Yubing Sun, Mingxu You 452-pos Board B273 MECHANICAL ACTIVATION OF EPIDERMAL GROWTH FACTOR RECEPTOR AT INTERCELLULAR ADHESIONS. Deborah E. Leckband , Vinh H. Vu, Yubo Zou, Brendan G. Sullivan 453-pos Board B274 CALCIUM-DEPENDENT STRENGTH OF THE INNER-EAR CADHERIN-23 ECTODOMAIN. Colin Klaus , Shuqi Wang, Bowen Jia, Avinash Jaiganesh, Marcos M. Sotomayor

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