Biophysical Society Bulletin | November 2022

Annual Meeting

Speakers: Keynote Speaker: Steven Block , Stanford University, USA Trapped for Life: My Career, One Molecule at a Time Olga Dudko , University of California, San Diego, USA Universality vs. Specificity in Synaptic Transmission Ruben Gonzalez, Jr. , Columbia University, USA Realtime Observation of Substrate Translocation Dynamics in an ABC Transporter Eugene Kim , Max Planck Institute, Frankfurt, Germany DNA Loop Extrusion Is a Conserved Mechanism among All Eukary otic SMC Complexes Pallav Kosuri , Salk Institute, USA Origami Movement Microscopy Sabrina Leslie , University of British Columbia, Canada Tether-Free, Single-Molecule Microscopy of DNA Interactions in Out-of-Equilibrium Conditions Felix Ritort , University of Barcelona, Spain RNA Cold Misfolding Wendy Thomas , University of Washington, USA How Some Single Receptor-Ligand Bonds Lock Instantly into a Long-Lived Force-Resistant State Jie Yan , National University of Singapore, Singapore The Mechanical Activation of Talin- and Vinculin-Mediated Rigidity Sensing of Extracellular Matrix Theory and Computation Subgroup Chair: Gregory A. Voth , University of Chicago, USA Speakers: Frauke Graeter , Heidelberg University, Germany Incorporating Chemistry into Classical Molecular Dynamics Simu lations of Proteins by Machine Learning Margaret Johnson , Johns Hopkins University, USA Bending Membranes Along Distinct Pathways of Protein Assem bly Juyong Lee , Kangwon National University, South Korea Accurate Prediction of Protein-Ligand Interactions by Combining Physical Energy Functions and Graph-neural Networks Janice Robertson , Washington University in St. Louis, USA Building a Molecular Model for Ion Channel and Transporter Stability in Membranes through a Partnership of Experiments and Computation Early Career Award Talk: Giulia Palermo , University of Califor nia, Riverside, USA Unraveling the CRISPR-Cas Revolution through the Lens of Com putational Biophysics Mid-Career Award Talk: Xuhui Huang , University of Wisconsin– Madison, USA Generalized Master Equation Models to Study Functional Dynam ics of Proteins

Igor Sharakhov , Virginia Tech, USA The 3D Genome Architecture in Human Malaria Vectors Devarajan (Dave) Thirumalai , University of Texas - Austin, USA Changing Structures of Chromosomes During a Cell Cycle: Role of Multiple Motors Yaojun Zhang , Johns Hopkins University, USA Mechanical Frustration of Phase Separation in the Cell Nucleus by Chromatin Nanoscale Approaches to Biology Subgroup Chair: Chan Cao , École Polytechnique Fédérale de Lausanne, Switzerland Speakers : Cynthia Burrows , University of Utah, USA Nanopore Sequencing of Nucleic Acids from Cells under Stress Reuven Gordon University of Victoria, Canada Rapid Single Protein Analysis by Nanoaperture Optical Tweezers Stefan Howorka , University College London, United Kingdom Probing and Piercing Lipid Bilayers with DNA Nanostructures Yana Reshetnyak , University of Rhode Island, USA pHLIP Technology for Imaging and Therapy: From Biophysics to Clinics Simon Scheuring , Cornell University, USA High-Speed Atomic Force Microscopy for Dynamic Single Molecule Structural Biology Philip Tinnefeld , Ludwig Maximillians University Munich, Ger many Enhancement Mechanisms for Single-molecule Sensing and Su perresolution with DNA Nanotech Physical Cell Biology Subgroup Chair: Ulrike Endesfelder , University of Bonn, Germany 2023 Program Chair: Pallav Kosuri , Salk Institute for Biological Studies, USA Speakers: Bogdan Bintu , University of California, San Diego, USA Spatial Transcriptions: Inducing Neurogenesis in the Adult Brain Khalid Salaita , Emory University, USA Caught Red-Handed: DNA Probes to Measure Cellular Traction Forces Srigokul Upadhyayula , University of California, Berkeley, USA Making the Invisible Visible: Imaging Subcellular Dynamics in Multicellular Systems Single-Molecule Forces, Manipulation, and Visualization Subgroup Co-Chairs: Zev Bryant , Stanford University, USA, and Wesley Wong , Harvard University, USA

November 2022

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