Biophysical Society Thematic Meeting | Trieste 2024

Emerging Theoretical Approaches to Complement Single-Particle Cryo-EM

Daily Schedule

14:35 – 15:10

Audrone Lapinaite, Arizona State University, USA Understanding the Molecular Mechanism of Genome Editors to Enhance their Precision and Targeting Scope Ivaylo Ivanov, Georgia State University, USA * Molecular Architecture and Functional Dynamics of the Pre-Incision Complex in the Nucleotide Excision DNA Repair Pathway Matthew Holcomb, Scripps Research Institute, USA * CRYOXKIT: Incorporation of Experimental Structural Density into Autodock for Improved Pose Prediction Milosz Wieczór, Gda ń sk University of Technology, Poland * Inferring the Conformational Landscape of Multistate Protein Assemblies Using Coarse-Grained Sampling of Transition Pathways

15:10 – 15:30

15:30 – 15:50

15:50 – 16:10

16:20 – 18:20

Poster Session I

Aula Magna Sala Attesa

18:20

Dinner on Own

Wednesday, October 23, 2024 8:00 – 18:00

Registration/Information

Aula Magna Sala Attesa

Session IV

Structure and Dynamics Rommie Amaro, University of California, San Diego, USA, Chair Janusz Bujnicki, International Institute of Molecular and Cell Biology, Poland Computational Modeling of RNA 3D Structures and Interactions – With and Without the Use of Experimental Data Pilar Cossio, Flatiron Institute, USA Probability Distributions from Individual Cryo-EM Images and Molecular Dynamics

8:30 – 9:05

9:05 – 9:40

9:40 – 10:15

Massimilliano Bonomi, Pasteur Institute, France Protein Structural Ensembles from 3D and 2D Cryo-EM Data

10:15 – 10:45

Coffee Break

Aula Magna Foyer

Session V

Cryo-EM Applications Gabriel Lander, Scripps Research Institute, USA, Chair

10:45 – 11:20

Elizabeth Kellogg, St. Jude Children’s Research Hospital, USA New Frontiers in Understanding and Improving RNA-Guided DNA Integration Using Cryo-EM and Machine Learning

11:20 – 11:55

Sebastian Glatt, Jagiellonian University Krakow, Poland Translational Control of Eukaryotic Gene Expression

11:55 – 12:15

Mingxu Hu, Tsinghua University, China * CRYOPROS: Addressing Preferred Orientation in Single-Particle Cryo-EM Through AI-Generated Auxiliary Particles

12:15 – 14:10

Lunch

Aula Magna Foyer

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