Biophysical Society Thematic Meeting | Trieste 2024

Emerging Theoretical Approaches to Complement Single-Particle Cryo-EM

Daily Schedule

Session VI

Methodological Advances in Cryo-EM Giulia Palermo, University of California, Riverside, USA, Chair Paul Emsley, MRC Laboratory of Molecular Biology, United Kingdom Model-Building, Refinement and Validation With COOT Sergio Cruz León, Max Planck Institute of Biophysics, Germany Enabling Visual Proteomics by High-Confidence 3D Template Matching Elsa Posani, International School for Advanced Studies, Italy * All Atom Molecular Dynamics Simulations Enable Ensemble Refinement of Flexible and Mismodelled Cryo-EM Derived RNA Structures Colin Kinz-Thompson, Rutgers University-Newark, USA * Measuring the Biomolecular Information Content Present in Structural Data Lorenzo Casalino, University of California, San Diego, USA * Harnessing Molecular Simulations to Design Stabilized Sars-Cov-2 S2 Antigens

14:10 – 14:45

14:45 – 15:20

15:20 – 15:40

15:40 – 16:00

16:00 – 16:20

16:20 – 18:20

Poster Session II

Aula Magna Sala Attesa

20:00 – 22:00

Banquet Dinner

Savoy Hotel Restaurant

Thursday, October 24, 2024 8:00 – 15:00

Registration/Information

Aula Magna Sala Attesa

Session VII

Structure and Dynamics Joanna Trylska, University of Warsaw, Poland, Chair

8:30 – 9:05

Natalie Strynadka, University of British Columbia, Canada Structure-Guided Drug Discovery Targeting Antibiotic Resistance Mechanisms in Staphlococcus Aureus Florence Tama, RIKEN Center for Computational Science, Japan Exploring Continuous Conformational Variability Via Cryo-EM Single-Particle Imaging and MD Simulations

9:05 – 9:40

9:40 – 10:15

David Taylor, University of Texas at Austin, USA Reengineering CRISPR-Cas Effector Complexes

10:15 – 10:45

Coffee Break

Aula Magna Foyer

Session VIII

Cryo-EM Applications Gabriel Lander, Scripps Research Institute, USA, Chair Wojciech Galej, European Molecular Biology Laboratory, France Structural Studies of the Pre-mRNA Splicing Machinery

10:45 – 11:20

11:20 – 11:40

Vivek Sharma, University of Helsinki, Finland * Molecular Insights into Mitochondrial Energy Production by Integrating Cryo Electron Microscopy and Biochemistry with Computer Simulations Erik Thiede, Flatiron Institute, USA * Towards Quantitative Recovery of Probability Densities from Cryo-EM

11:40 – 12:00

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