Biophysical Society Thematic Meeting | Trieste 2024

Emerging Theoretical Approaches to Complement Single-Particle Cryo-EM

Daily Schedule

12:00 – 14:00

Lunch

Aula Magna Foyer

Session IX

Methodological Advances in Cryo-EM Joanna Trylska, University of Warsaw, Poland, Chair

14:00 – 14:35

James Fraser, University of California, San Francisco, USA Uncovering Protein Ensembles: Automated Multiconformer Model Building for Cryo-EM Proteins, Nucleic Acids, Solvent, and Ligands Mateusz Sikora, Jagiellonian University, Poland Integrative Modeling of Glycoproteins, Lessons from the Pandemic

14:35 – 15:10

15:10

Free Time/Dinner on Own

Friday, October 25, 2024 8:00 – 12:00

Registration/Information

Aula Magna Sala Attesa

Session X

Structure and Dynamics Lorenzo Casalino, University of California, San Diego, USA, Chair

8:30 – 9:05

Michele Vendruscolo, University of Cambridge, United Kingdom Determination of Protein Structural Ensembles Using Cryo-Electron Microscopy Erik Lindahl, Stockholm University, Sweden Modeling Conformational Transition of Proteins by Combining Cryo-EM, Alphafold and Molecular Simulations Isabelle Rouiller, University of Melbourne, Australia Characterizing the Conformational Landscape of the Hexameric VCP Complex from 2D Cryo-EM Images Using Molecular Dynamics Simulation Cryo-EM Applications Alessandra Magistrato, International School for Advanced Studies, Italy, Chair Jakub Rzeszótko, Max Planck Institute of Molecular and Cell Biology and Genetics, Germany * Advancing Structural Insights into Small Membrane Transporters Through SP Cryo-EM: Unraveling the Regulatory Mechanisms of SLC26 Family Nathan Bernhardt, National Institutes of Health, USA * What Determines the Dwell-Time of a Bound Lipid? Interpreting Lipid Densities in Structural Data Using Molecular Dynamics Simulations and Specialized Tools for Their Analysis Tatiana Shugaeva, KTH Royal Institute of Technology, Sweden * Accurate Protein Fitting into Cryo-EM Maps Using Multiple Conformers Generated by Alphafold2 Coffee Break Aula Magna Foyer

9:05 – 9:40

9:40 – 10:15

10:15 – 10:45

Session XI

10:45 – 11:05

11:05 – 11:25

11:25 – 11:45

11:45 – 12:00

Closing Remarks and Biophysical Journal Poster Awards Giulia Palermo, University of California, Riverside, USA

*Short talks selected from among submitted abstracts

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