Program Book

4:00 pm –6:00 pm , R oom 306 Platform Muscle: Fiber and Molecular Mechanics and Structure Co-Chairs

2278-P lat 5:30 pm QUANTITATIVE ANALYSIS OF SINGLE-MOLECULE FORCE SPECTROSCOPY DATA ON CHROMATIN FIBERS. Kurt Andresen , He Meng, John van Noort 2279-P lat 5:45 pm KINETICS AND ENERGETICS OF BIOMOLECULAR FOLDING AND BINDING. Christopher A. Pierse , Olga Dudko

T U

Jorge Alegre-Cebollada, Columbia University John Trinick, Leeds University, United Kingdom 2288-P lat 4:00 pm

E S

4:00 pm –6:00 pm , R oom 305 Platform Membrane Dynamics

HARMONIC FORCE SPECTROSCOPY REVEALS A FORCE- VELOCITY CURVE FROM A SINGLE HUMAN BETA CARDIAC MYOSIN MOTOR. Jongmin Sung , Suman Nag, Christian Vestergaard, Kim Mortensen, Henrik Flyvbjerg, James Spudich 2289-P lat 4:15 pm THREE-DIMENSIONALLY CONSTRAINED ACTOMYOSIN MOTILITY ON OXIDE COATED SEMICONDUCTOR NANOWIRES. Alf Mansson , Lasse ten Siethoff, Mercy Lard, Johanna Generosi, Håkan Andersson, Heiner Linke 2290-P lat 4:30 pm THE MINIMAL GROUP SIZE FOR GLOBALLY COORDINATED STEPPING OF MUSCLE MYOSINS DEPENDS ON ATP HYDROLYSIS FREE ENERGY. Lennart Hilbert , Linda Kachmar, Michael C. Mackey, Anne-Marie Lauzon 2291-P lat 4:45 pm TOWARD THE REALIZATION OF A SARCOMERE-LIKE MACHINE. Luca Melli , Pasquale Bianco, Giulia Falorsi, Luca Salvi, Giovanna Coceano, Manuela Maffei, Dan Cojoc, Vincenzo Lombardi 2292-P lat 5:00 pm LARGE-SCALE MODULATION OF TITIN ELASTICITY BY S-GLUTATHIONYLATION OF CRYPTIC CYSTEINES. Jorge Alegre-Cebollada , Pallav Kosuri, David Giganti, Edward Eckels, Jaime Andrés Rivas-Pardo, Nazha Hamdani, Wolfgang A. Linke, Julio M. Fernández 2293-P lat 5:15 pm THE EFFECT OF INTERFILAMENT SPACING ON THICK FILAMENT STRUCTURE AND CALCIUM ACTIVATION IN SKELETAL MUSCLE. Elisabetta Brunello , Marco Caremani, Luca Fusi, Massimo Reconditi, Marco Linari, Theyenchery Narayanan, Gabriella Piazzesi, Malcolm Irving, Vincenzo Lombardi 2294-P lat 5:30 pm CRYO-EM OF Z-DISCS ISOLATED FROM HONEYBEE FLIGHT MUSCLE. Mara Rusu, Kenneth A. Taylor, John Trinick 2295-P lat 5:45 pm CRYO-EM STRUCTURES OF THE ACTIN:TROPOMYOSIN FILAMENT REVEAL THE MECHANISM FOR THE TRANSITION FROM C- TO M-STATE. Duncan Sousa , Scott Stagg, M. Elizabeth Stroupe 7:30 pm –9:30 pm , R oom 134 Workshop Knocking Down or Turning Off: Down-Regulation of Protein Expression Chair Suzanne Scarlata, Stony Brook University 2296-W kshp 7:30 pm MOONLIGHTING PROTEINS: HOW THE LIPID-SIGNALING ENZYME PHOSPHOLIPASE C-BETA REGULATES RNA SILENCING. Suzanne Scarlata , Finly Philip, Shriya Sahu

D A Y

Co-Chairs Himanshu Khandelia, University of Southern Denmark, Denmark Blake Mertz, West Virginia University 2280-P lat 4:00 pm MECHANISM OF NUTRIENT DEPRIVATION I NDUCED TRIACYLGLYCERIDE ACCUMULATION IN ALGA INDICATED BY FLUORESCENCE HYPERSPECTRAL IMAGING. Ryan W. Davis , Howland D.T. Jones, Jerilyn A. Timlin, Seema Singh 2281-P lat 4:15 pm PROBING THE CELL GROWTH-DEPENDENT SPATIAL DISTRIBUTION AND DYNAMICS OF PROTEINS INSERTED IN THE BACTERIAL OUTER MEMBRANE. Patrice Rassam 2282-P lat 4:30 pm international travel awardee STRAIN RATE-DEPENDENT MEMBRANE RESERVOIR- KEY TO CHONDROCYTE DEATH BY IMPACT. Eng Kuan Moo , Matthias Amrein, Marcelo Epstein, Mike Duvall, Noor Azuan Abu Osman, Belinda Pingguan-Murphy, Walter Herzog 2283-P lat 4:45 pm MICROVESICLES : WHAT’S PLASMA MADE OF? Alain R. Brisson , Nicolas Arraud, Romain Linares, Sisareuth Tan, Celine Gounou 2284-P lat 5:00 pm AREA PER LIPID OF MEMBRANES FROMNATURAL ABUNDANCE SOLID-STATE 13 C NMR SPECTROSCOPY. Trivikram R. Molugu , Avigdor Leftin, Constantin Job, Michael F. Brown 2285-P lat 5:15 pm BINDING OF NEUROTRANSMITTERS TO LIPID MEMBRANES. Günther H. Peters , Mikkel Werge, Maria N. Elf-Lind, Chunhua Wang, Nicolaj Cruys-Bagger, Gustavo F. Velardez, Jesper J. Madsen, Peter Westh 2286-P lat 5:30 pm IN SILICO STUDIES OF ASYMMETRIC MEMBRANES PERTURBATIONS CAUSED BY DYNAMIC AGGREGATION OF A CELL-PENETRATING PEPTIDE. Jean Helie , Mickael Lelimousin, Charlotte M. Deane, Francesca Milletti, Mark SP Sansom 2287-P lat 5:45 pm RESHAPING BIOLOGICAL MEMBRANES: FROM MOLECULAR INTERACTIONS TO MACROSCOPIC MECHANICS. Mijo Simunovic , Patricia Bassereau, Gregory A. Voth

127

Biophysical Society 58 th Annual Meeting, San Francisco, California