Program Book

3196-P lat

9:00 am

3207-P lat 9:45 am MEMPROTMD: MEMBRANE PROTEIN STRUCTURES AND SIMULATIONS. Phillip J. Stansfeld , Mark S. P. Sansom 3208-P lat 10:00 am STRUCTURES OF BLOOD COAGULATION FACTOR VIII IN SOLUTION AND MEMBRANE-BOUND. Alexey Y. Koyfman , Jaimy L. Miller, Daniela Dalm, Kirill Grushin, Svetla Stoilova-McPhie

education travel awardee ELECTROFORMATIONOF UNIFORMLY SIZEDGIANT LIPOSOMES WITH FUNCTIONAL MEMBRANE PROTEINS. You Jung Kang , Harrison S. Wostein, Sheereen Majd 3197-P lat 9:15 am DNA SENSING WITH THE MSPA NANOPORE USING VARIABLE VOLTAGE. Ian M. Derrington , Kyle W. Langford, Andrew H. Laszlo, Elizabeth Manrao, Henry Brinkerhoff, Jacquelyn E. Blum, Jens H. Gundlach 3198-P lat 9:30 am SHRINKING NANOCAPILLARIES TO LOW NOISE NANOPORES FOR SINGLE MOLECULE DETECTION. Lorenz J. Steinbock , Swati Krishnan, Roman Bulushev, Aleksandra Radenovic 3199-P lat 9:45 am NOVEL QUANTUM DOT PROBES FOR SINGLE-MOLECULE BIOPHYSICS. Sara M. Wichner , Mark A. DeWitt, Bruce E. Cohen, Ahmet Yildiz 3200-P lat 10:00 am SPLIT-FP CONJUGATED METAL NANOPARTICLE RAMAN NANOPROBES FOR ULTRA-SENSITIVE MOLECULAR DETECTION. Tugba Koker , Fabien Pinaud SUPERRESOLUTIONMICROSCOPY REVEALS NANOMETER-SCALE REORGANIZATION OF MG53 ASSOCIATED WITH MEMBRANE REPAIR. Mingzhai Sun , Jiaqing Huang, Kristyn Gumpper, Gejing De, Matthew Sermersheim, Pei-Hui Lin, Haichang Li, Pu Duann, Jianjie Ma 3202-P lat 8:30 am INVESTIGATING THE CELL MEMBRANE VIA SINGLE PARTICLE TRACKING, BAYESIAN INFERENCE AND HYDRODYNAMIC FORCE APPLICATION. Maximilian U. Richly , Silvan Türkcan, Cedric Bouzigues, Michel R. Popoff, Jean-Baptiste Masson, Jean-Marc Allain, Antigoni Alexandrou 3203-P lat 8:45 am THE MOLECULAR STRUCTURE OF THE LIQUID ORDERED PHASE. Edward R. Lyman , Alex Sodt, Klaus Gawrisch, Richard Pastor 3204-P lat 9:00 am A LIPID BOUND ACTIN MESHWORK ORGANIZES LIQUID PHASE SEPARATION IN MODEL MEMBRANES. Alf Honigmann , Sina Sadeghi, Keller Jan, Stefan W. Hell, Christian Eggeling, Richard Vink 3205-P lat 9:15 am THE IMPACT OF OXIDIZED PHOSPHOLIPIDS ON LIPID MEMBRANES: CONSEQUENCES FOR MITOCHONDRIAL APOPTOSIS. Martin Lidman, Sarka Pokorna, Marcus Wallgren, Martin Hof, Gerhard Gröbner 3206-P lat 9:30 am education travel awardee G-PROTEIN-COUPLED RECEPTOR ACTIVATION INVESTIGATED USING SMALL-ANGLE NEUTRON SCATTERING. Suchithranga M. D. C. Perera , Utsab Shrestha, Udeep Chawla, Andrey V. Struts, Shuo Qian, Michael F. Brown, Xiang-Qiang Chu 8:15 am –10:15 am , R oom 305 Platform Membrane Structure Co-Chairs Edward Lyman, University of Delaware Gerhard Groebner, Umeå University, Sweden 3201-P lat 8:15 am

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8:15 am –10:15 am , R oom 306 Platform Dynamics of Ligand Binding and Coupled Motions

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Co-Chairs Vanessa Ortiz, Columbia University Jiahui Tian, Oak Ridge National Laboratory 3209-P lat 8:15 am

D A Y

MAPPING ALLOSTERIC COMMUNICATION PIPELINES IN GPCRS FROM MICROSECOND TIMESCALE MOLECULAR DYNAMICS SIMULATIONS. Supriyo Bhattacharya , Nagarajan Vaidehi 3210-P lat 8:30 am MOLECULAR DYNAMICS SIMULATIONS OF THE CATALYTIC SUBUNIT OF PROTEIN KINASE A REVEAL NEW INSIGHT INTO THE CATALYTIC PROCESS. Jianhui Tian , Loukas Petridis, WilliamT. Heller 3211-P lat 8:45 am OXYGEN-AFFINITY OF HEMOGLOBIN IS REGULATED BY EFFECTOR-LINKED DYNAMIC MODULATIONS OF HIGH- FREQUENCY THERMAL FLUCTUATIONS. Takashi Yonetani 3212-P lat 9:00 am DISCOVERING AND MANIPULATING PROTEIN CONFORMATIONAL HETEROGENEITY AND FUNCTION. Daniel Keedy , Henry van den Bedem, Justin Rettenmaier, James Wells, James Fraser 3213-P lat 9:15 am DETERMINATION OF THE INDIVIDUAL ROLES OF THE LINKER RESIDUES IN THE INTER-DOMAIN MOTIONS OF CALMODULIN USING NMR CHEMICAL SHIFTS. Predrag Kukic , Carlo Camilloni, Andrea Cavalli, Michele Vendruscolo 3214-P lat 9:30 am THE ROLE OF PROTEIN DYNAMICS IN CALMODULIN TARGET RECOGNITION. Laurel Hoffman , Xu Wang, Margaret S. Cheung, John A. Putkey, M. Neal Waxham 3215-P lat 9:45 am INSIGHTS INTO ALLOSTERY FROM THE LOCAL ELASTIC CONSTANTS OF A PROTEIN. Andre A. S. T. Ribeiro, Vanessa Ortiz 3216-P lat 10:00 am A SUBSTRATE CHANNEL IN NITROGENASE REVEALED BY A MOLECULAR DYNAMICS APPROACH. Dayle M. Smith , Simone Raugei, Karamatullah Danyal, Lance Seefeldt

9:00 am –1:00 pm , H all D Biomolecular Discovery Dome 10:30 am –11:15 am , H all D Coffee Break

169

Biophysical Society 58 th Annual Meeting, San Francisco, California