Program Book

Enzyme Function and Regulation (Boards #B143–#B171)

3401-P os B oard #B129 ORIGIN OF ENTHALPIC DEPLETION FORCES. Liel Sapir , Daniel Harries 3402-P os B oard #B130 STATISTICAL MECHANICAL MODELS FOR ANALYZING THE SITE-SPECIFIC FOLDING OF HELIX-TURN-HELIX MOTIFS. Jason K. Lai , Jan Kubelka 3403-P os B oard #B131 TOWARDS A TEST OF THE AGGREGATION HYPOTHESIS IN HUNTINGTON’S DISEASE USING β -HAIRPIN ENHANCING MOTIFS. Sascha Rode , Kenneth Drombosky, Ronald Wetzel 3404-P os B oard #B132 SALT EFFECTS ON FOLDING OF A HELICAL MINI PROTEIN VILLIN HEADPIECE SUBDOMAIN HP36 STUDIED BY GENERALIZED-ENSEMBLE SIMULATIONS. Takao Yoda , Yuji Sugita, Yuko Okamoto 3405-P os B oard #B133 SIMULATION MODEL OF PROTEIN TRANSPORT AND STABILIZATION BY GROEL/ES. Apichart Linhananta 3406-P os B oard #B134 NON LOCAL INTERACTIONS ARE ESSENTIAL ELEMENTS OF THE INITIATION AND GUIDANCE OF THE FOLDING PATHWAY OF PROTEINS. Elisha Haas , Tomer Orevi, Gil Rahamim, Dan Amir 3407-P os B oard #B135 COMPUTATIONAL STUDIES OF THE FORMATION OF PEROXIREDOXIN DIMERS. Jiajie Xiao , Freddie R. Salsbury 3408-P os B oard #B136 INVESTIGATING CHARACTERISTICS OF FOLDING CORES FROM ANALYSES OF FOLDING MECHANIAMS ON MULTI-TRANSITION PROTEINS BY MEANS OF A COARSE-GRAINED GO MODEL. Masatake Sugita , Takeshi Kikuchi 3409-P os B oard #B137 EFFECTS OF ENERGETIC HETEROGENEITY ON PROTEIN FOLDING DYNAMICS ACROSS MANY NON-HOMOLOGOUS PROTEINS. Claude Sinner , Benjamin Lutz, Abhinav Verma, Alexander Schug 3410-P os B oard #B138 AROMATIC AMINO ACIDS PROMOTE PEPTIDE FOLDING BY REDUCING BACKBONE HYDRATION. Olivier Bignucolo , Stephan Grzesiek, Simon Berneche 3411-P os B oard #B139 PH DEPENDENT CONFORMATIONAL CHANGE OF HEPCIDIN AND ITS PRECURSOR PROTEIN, PRO-HEPCIDIN. Kana Ohshige , Shigeru Shimamoto, Yuji Hidaka 3412-P os B oard #B140 MYOSIN UNC-45 CHAPERONE: THE ROLE OF ITS DOMAINS INTHE INTERACTIONWITHTHE MYOSINMOTOR DOMAIN. Paul Bujalowski , Paul Nicholls, Jose Barral, Andres Oberhauser 3413-P os B oard #B141 POLY-(R)-3-HYDROXYBUTYRATE-MODIFIED PROTEINS. Rosetta N. Reusch 3414-P os B oard #B142 GFP VARIANTS WITH ALTERNATIVE STRANDS: PROTEASE SENSOR DESIGN AND THEIR THERMODYNAMIC ANALYSIS. Keunbong Do , Steven G. Boxer

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3415-P os B oard #B143 STEERED MOLECULAR DYNAMICS SIMULATIONS OF NAD UNBINDING FROM GAPDH AND LDH. Tsvetan Aleksandrov , Igor V. Uporov, Rahul Nori, Kathryn A. Thomasson 3416-P os B oard #B144 COMPUTATIONAL AND EXPERIMENTAL STUDY OF KETOREDUCTASE ENANTIOSELECTIVITY. Elizabeth Noey , Jiyong Park, K.N. Houk 3417-P os B oard #B145 IN SUPPORT OF NITRIC OXIDE DIOXYGENASE FUNCTION: ALGAL HEMOGLOBINS AND THEIR REDUCTION PARTNERS. Manish Shandilya , Amit Kumar, Sheetal Uppal, Suneel Kateriya, Suman Kundu 3418-P os B oard #B146 education travel awardee MAPPING THE SUBSTRATE BINDING SITES OF THE INTEGRAL MEMBRANE METHYLTRANSFERASE ICMT BY MUTATIONAL ANALYSIS. Melinda M. Diver , Stephen B. Long 3419-P os B oard #B147 REGULATION OF CREATINE KINASE BY ASB9. Deepa Balasubramaniam , Jamie Schiffer, Elizabeth Komives 3420-P os B oard #B148 UNDERSTANDING FUNCTIONAL EVOLUTION IN THE ALKALINE PHOSPHATASE SUPERFAMILY. Alexandre H. Barrozo , Alexandra Pires Carvalho 3421-P os B oard #B149 minority affairs travel awardee DID CLASS 1 AND CLASS 2 AMINOACYL TRNA SYNTHETASES DESCEND FROM GENETICALLY COMPLIMENTARY, CATALYTICALLY ACTIVE ATP-BINDING MOTIFS? Mariel Jimenez , Tishan Williams, A. Katiria González-Rivera, Li Li, Ozgün Erdogan, Charles W. Carter, Jr. 3422-P os B oard #B150 ANALYSES OF THE INTERACTION BETWEEN LIPOCALIN-TYPE PROSTAGLANDIN D SYNTHASE AND SUBSTRATE OR PRODUCT. Yutaro Fukuda , Takahiro Maruno, Yuji Kobayashi, Tadayasu Ohkubo, Kosuke Aritake, Yoshihiro Urade, Yuji Hidaka, Shigeru Shimamoto 3423-P os B oard #B151 THE EVOLUTIONARY CONSTRAINTS IMPOSED ON TYROSINE HYDROXYLATION BY ITS BEGINNINGS AS A PHENYLALANINE HYDROXYLASE; STUDIES OF THE POLYPEPTIDE LOOP DETERMINING THE SUBSTRATE SPECIFICITY. Ewa Nowara 3424-P os B oard #B152 STRUCTURAL AND FUNCTIONAL BASIS FOR SUBSTRATE SPECIFICITY AND CATALYSIS OF LEVAN FRUCTOTRANSFERASE. Sangkee Rhee , Jinseo Park 3425-P os B oard #B153 CO RECOMBINATION IN HUMAN IDO AND TDO - A COMPARISON. Karin Nienhaus , G. Ulrich Nienhaus 3426-P os B oard #B154 MOLECULAR DYNAMICS SIMULATIONS OF THE PROTON TRANSFER REACTION BETWEEN THE CATALYTIC RESIDUES IN HTLV-I PROTEASE. Shuhua Ma , Natalie Petrillo, Kimberly Vogt

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Biophysical Society 58 th Annual Meeting, San Francisco, California