Program Book

4:00 pm –6:00 pm , R oom 305 Platform Membrane Physical Chemistry I

211-P lat 5:15 pm UNDERSTANDING THE MOLECULAR MECHANISMS BY WHICH ALLOSTERIC LIGANDS INHIBITTHE RNA POLYMERASE FROM THE HEPATITIS C VIRUS. Brittny Davis , Ian Thorpe 212-P lat 5:30 pm MOLECULAR DYNAMICS SIMULATIONS OF RIBOSOMES: INTEGRATING THEORY AND EXPERIMENT. Serdal Kirmizialtin, Karissa Y. Sanbonmatsu 213-P lat 5:45 pm RESOLVING THE MECHANISMS OF BACTERIAL RESISTANCE TO MACROLIDE ANTIBIOTICS. Anna Pavlova , James C. Gumbart Co-Chairs Liming Ying, Imperial College London, United Kingdom Astrid Graslund, Stockholm University, Sweden 214-P lat 4:00 pm KINETICS OF METAL AMYLOID-BETA BINDING AND EFFICACY OF LIGANDS TARGETING METAL AMYLOID-BETA INTERACTIONS. Thomas Branch, Martin Evans, Mauricio Barahona, Liming Ying 215-P lat 4:15 pm AMYLOIDS.HOWTO STUDY THEMWITH TWO-DIMENSIONAL CORRELATION SPECTROSCOPY. Jose Luis R. Arrondo , Jon Ander Nieto, Igor De la Arada 216-P lat 4:30 pm SURFACE-CATALYZED NUCLEATION OF AMYLOIDOGENIC PEPTIDES BY PEPTIDE-SPECIFIC TEMPLATES. Marisa Rubio , Andrew D. Miranker 217-P lat 4:45 pm FORMATION OF DYNAMIC SOLUBLE SURFACTANT-INDUCED AMYLOID BETA PEPTIDE AGGREGATION INTERMEDIATES. Axel Abelein, Jorn D. Kaspersen, Soren B. Nielsen, Grethe V. Jensen, Gunna Christiansen, Jan S. Pedersen, Jens Danielsson, Daniel E. Otzen, Astrid Graslund 218-P lat 5:00 pm AGGREGATION OF OXIDATION-MIMICKING MUTANTS OF GAMMA-D CRYSTALLIN SUPPORTS A DOMAIN SWAPPING MODEL. Eugene Serebryany , Jonathan A. King 219-P lat 5:15 pm APPLICATIONS OF TWO-DIMENSIONAL INFRARED SPEC- TROSCOPY TO STUDIES OF STRUCTURE AND MECHANISM IN LENS CRYSTALLIN PROTEIN AGGREGATES. Tianqi O. Zhang , Sean D. Moran, Martin T. Zanni 220-P lat 5:30 pm UNRAVELING THE MECHANISM OF CELL DEATH INDUCED BY CHEMICAL AND PROTEIN FIBRILS. Olivier Julien , Martin Kampmann, Michael C. Bassik, Vincent J. Venditto, Julie A. Zorn, Arnold L. Rheingold, Jonathan S. Weissman, James A. Wells 221-P lat 5:45 pm ATP-MG+2 MEDIATED ASSEMBLY OF RUBISCO ACTIVASE INVESTIGATED USING FLUORESCENCE CORRELATION SPECTROSCOPY. Manas Chakraborty , Agnieszka Kuriata, J Nathan Henderson, Michael E. Salvucci, Rebekka Wachter, Marcia Levitus 4:00 pm –6:00 pm , R oom 304 Platform Assemblies and Aggregates

F R I D A Y

S A T U R D A Y U N D A Y

Co-Chairs Beate Klösgen, University of Southern Denmark, Denmark Christopher Rowley, Memorial University of Newfoundland, Canada 222-P lat 4:00 pm ELECTRIC FIELD INDUCED CO-LOCALIZATION OF MEM- BRANE COMPONENTS IN SUPPORTED LIPID BILAYERS DE- TECTED BY SECONDARY ION MASS SPECTROMETRY. Monica M. Lozano , Jennifer Hovis, Frank R. Moss, Krishna Kumar, Steven G. Boxer 223-P lat 4:15 pm LIPID BILAYER STRUCTURE AND DYNAMICS STUDIED WITH MOLECULAR DYNAMICS SIMULATIONS AND NMR MEASUREMENTS. Tiago Ferreira, Daniel Topgaard, Samuli O H Ollila 224-P lat 4:30 pm UNDERSTANDING THE MEMBRANE PERMEABILITY OF HYDROGEN SULFIDE THROUGH MOLECULAR DYNAMICS SIMULATIONS USING A POLARIZABLE FORCE FIELD. Christopher N. Rowley , Saleh Riahi 225-P lat 4:45 pm THE INTERACTION OF RESVERATROL WITH DPPC BILAYERS - A BIOPHYSICAL CONTRIBUTION ON THE MEDITERRANEAN DIET. Alexis de Ghellinck, Chen Shen, Paul Stein, Giovanna Fragneto, Michele Sferrazza, Beate M. Klösgen 226-P lat 5:00 pm DMPC: A REMARKABLE EXCEPTION TO THE TOCOPHEROL’S MEMBRANE PRESENCE. Drew Marquardt , Justin A. Williams, Jacob J. Kinnun, Norbert Kucerka, Jeffrey Atkinson, Stephen R. Wassall, John Katsaras, Thad A. Harroun 227-P lat 5:15 pm LIPID MEDIATED HETEROGENEITY IN CISPLATIN RESISTANCE IN CANCER CELL LINES. Krishnan Raghunathan , Aarif Ahsan, Dipankar Ray, Mukesh Nyati, Sarah Veatch 228-P lat 5:30 pm CREATING FREE-STANDING LIPID BILAYERS ON FUSED SILICA SUBSTRATES WITH NANOGRATING STRUCTURE. Po-Yu Peng , Po-Chieh Chiang, Ling Chao 229-P lat 5:45 pm MICROFLUIDIC FABRICATION OF GIANT UNILAMELLAR LIPID VESICLES WITH CONTROLLED MICRODOMAIN FORMATION. Laura R. Arriaga , Sujit S. Datta, Shin-Hyun Kim, Esther Amstad, Thomas E. Kodger, Francisco Monroy, David A. Weitz

4:00 pm –6:00 pm , R oom 306 Platform Cell Mechanics and Motility I

Co-Chairs Ariel Livne, Weizmann Institute of Science, Israel Kellie Beicker, University of North Carolina at Chapel Hill 230-P lat 4:00 pm CELL REORIENTATION UNDER CYCLIC STRETCHING. Ariel Livne , Eran Bouchbinder, Benjamin Geiger

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Biophysical Society 58 th Annual Meeting, San Francisco, California