Program Book

633-P os B oard #B388 EVALUATION OF OPTICAL UPSTROKE MORPHOLOGY IN THE RABBIT HEART: OPTICAL MAPPING AND TRANSMURAL MICROELECTRODE RECORDINGS. Rūta Vosyliūtė , Regina Mačianskienė, Irma Martišienė, Antanas Navalinskas, Rimantas Treinys, Birutė Vaidelytė, Gintautė Rutkauskaitė, Jonas Jurevičius 634-P os B oard #B389 MECHANISMS UNDERLYING NA + /K + -ATPASE INHIBITION-IN- DUCED MITOCHONDRIAL DYSFUNCTION AND ABNORMAL ACTION POTENTIALS. Qince Li, Lufang Zhou 635-P os B oard #B390 INHIBITION OF MITOCHONDRIAL NA + /CA 2+ EXCHANGER SUPPRESSES ISCHEMIA/REPERFUSION-INDUCED REENTRY IN MONOLAYERS OF CARDIOMYOCYTES. Soroosh Solhjoo , Brian O’Rourke  Excitation-Contraction Coupling I (Boards #B391–#B420) 636-P os B oard #B391 RAPTOR ABLATION IN SKELETAL MUSCLE AFFECTS THE STRUCTURE AND FUNCTION OF THE EXCITATION- CONTRACTION COUPLING MACROMOLECULAR COMPLEX. Ruben Lopez, Barbara Mosca, Leda Bergamelli, Markus A. Ruegg, Florian C. Bentzinger, Michael N. Hall, Susan Treves, Francesco Zorzato 637-P os B oard #B392 MODIFICATION OF CARDIAC RYANODINE RECEPTOR GATING BY A PEPTIDE FROM THE CENTRAL DOMAIN OF THE RYR2. Andrea Faltinova, Alexandra Zahradnikova 638-P os B oard #B393 ULTRASTRUCTURAL QUANTIFICATION OF ELECTRON-DENSE STRINGS IN THE SARCOPLASMIC RETICULUM OF RAT HEART CELLS. Lin-Lin Li, Xue-Xin Fan, Shi-Qiang Wang 639-P os B oard #B394 RESOLVING THE CALCIUM RELEASE MACHINERY OF MAMMALIAN FAST- AND SLOW-TWITCH SKELETAL MUSCLE. Isuru D. Jayasinghe , Michelle Munro, David Baddeley, Bradley S. Launikonis, Christian Soeller 640-P os B oard #B395 LETHAL EXERTIONAL STROKES IN RYR1 Y522S/WT AND CASQ1- NULL MICE ARE PREVENTED BY DRUGS USED TO TREAT MALIGNANT HYPERTHERMIA IN HUMANS. Antonio Michelucci , Alessandro De Marco, Laura Pietrangelo, Cecilia Paolini, Susan L. Hamilton, Feliciano Protasi 641-P os B oard #B396 CLIC-2 DETERMINES FKBP12 AND FKBP12.6 ASSOCIATION WITH RYANODINE RECEPTOR CALCIUM RELEASE CHANNELS. Gregory A. Steele, Nicole A. Beard, Philip G. Board, Angela F. Dulhunty 642-P os B oard #B397 DYAD CONTENT IS REDUCED IN CARDIAC MYOCYTES OF MICE WITH IMPAIRED CALMODULIN REGULATION OF RYR2. Manuela Lavorato , Huang Taiqin, Venkat Ramesh Iyer, Gerhard Meissner, Clara Franzini-Armstrong 643-P os B oard #B398 SILENCING RYR3 ELIMINATES PARAJUNCTIONAL FEET AND CA SPARKS IN ZEBRA FISH TAIL MYOTOMES. Stefano Perni , Clara Franzini-Armstrong, Stephen Hollingworth, Stephen M. Baylor

644-P os B oard #B399 CHEMICAL UNCOUPLING THE DHPR-RYR1 COMPLEX BY SUBSTITUTED HALOGENATED BIPHENYLS AND DIPHENYLETHERS. Yassaman Niknam , Wei Feng, Gennady Cherednichenko, Yao Dong, Isaac Pessah 645-P os B oard #B400 ALTERED ION CHANNEL PROPERTIES OF RYANODINE RECEPTOR FROM HEART MICE LACKING CALSTABIN2. Nathalie Saint , Albano C. Meli, Valerie Scheuermann, Alain Lacampagne 646-P os B oard #B401 MODULATION OF DHPR INACTIVATION BY RYR1 ACTIVITY IN MOUSE SKELETAL MUSCLE FIBERS. Zoita Andronache, Werner Melzer 647-P os B oard #B402 CA 2+ INFLUX MEDIATED BY REVERSE MODE OF NA + /CA 2+ EXCHANGER IS ENHANCED IN MALIGNANT HYPERTHERMIA SKELETAL MUSCLE. Francisco Altamirano , Jose M. Eltit, Isaac Pessah, Paul D. Allen, Jose R. Lopez 648-P os B oard #B403 MYOFILAMENT CA 2+ DESENSITIZATION IS ASSOCIATED WITH REDUCED L-TYPE CA 2+ CHANNEL ACTIVITY MEDIATED BY NEURONAL NITRIC OXIDE SYNTHASE IN LEFT VENTRICULAR MYOCYTES FROM MURINE HEARTS. Yue Wang, Chun Zi Jin, Sung Joon Kim, Yin Hua Zhang 649-P os B oard #B404 RGK PROTEINS INHIBIT SLOW, DEPOLARIZATION- DEPENDENT CA 2+ ENTRY INTO CULTURED MYOTUBES. Christin F. Romberg, Donald Beqollari, Ulises Meza, Roger A. Bannister 650-P os B oard #B405 EXPRESSION OF THE EMBRYONIC CAV1.1 SPLICE VARIANT IN ADULT MICE ALTERS EXCITATION-CONTRACTION COUPLING BUT DOES NOT CAUSE DYSTROPHIC MYOTONIA. Nasreen Sultana , Ariane Benedetti, Monika Sztretye, Beatrix Dienes, Peter Szentesi, Petronel Tuluc, Serena Quarta, Gerald J. Obermair, Christoph Schwarzer, Michaela Kress, Laszlo Csernoch, Bernhard E. Flucher 651-P os B oard #B406 THE DHPR CALCIUM CURRENT IN MAMMALIAN SKELETAL MUSCLE: PHYSIOLOGICAL NECESSITY OR TOLERATED EVOLUTIONARY REMNANT? Anamika Dayal, Kai Schrötter , Werner Melzer, Christoph Schwarzer, Manfred Grabner 652-P os B oard #B407 CA 2+ UPTAKE BY THE TUBULAR (T-) SYSTEM MEMBRANE OF RAT FAST-TWITCH FIBRES. Tanya R. Cully , Joshua N. Edwards, Thomas R. Shannon, Bradley Launikonis 653-P os B oard #B408 POSSIBLE ROLE FOR THE PHOSHORYLATED TAIL IN RETAINING CSQ2 TO SPECIFIC SITES WITHIN THE SECRETORY PATHWAY. Cristine Smoczer , Naama H. Sleiman, Steven Cala 654-P os B oard #B409 MICROTUBULE INTEGRITY IS ESSENTIAL TO JUNCTIONAL SR PROTEIN DELIVERY. Naama H. Sleiman , Cristine Somczer, Steven E. Cala 655-P os B oard #B410 PROTON FLUXES ACROSS THE TUBULAR (T-) SYSTEM MEMBRANE OF RAT FAST-TWITCH FIBRES. Bradley S. Launikonis, Tanya R. Cully , Laszlo Csernoch, D. George Stephenson

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Biophysical Society 58 th Annual Meeting, San Francisco, California