Program Book

8:15 am –10:15 am , R oom 132/133 Platform Advances in Single-Molecule Spectroscopy Co-Chairs Lori Goldner, University of Massachusetts Amherst Matthew Ferguson, National Cancer Institute 1127-P lat 8:15 am SINGLE MOLECULE IMAGING IN VIVO DETERMINES POST-TRANSCRIPTIONAL RNA PROCESSING DYNAMICS. Matthew L. Ferguson , Antoine Coulon, Valeria de Turris, Murali Palangat, Carson C. Chow, Daniel R. Larson 1128-P lat 8:30 am COMBINED SINGLE MOLECULE RECOGNITION IMAGING AND FORCE SPECTROSCOPY TO STUDY THE INTERACTIONS BETWEEN UNCOUPLING PROTEINS AND PURINE NUCLEOTIDES. Melanie Köhler , Gabriel Pürstinger, Rong Zhu, Anne Rupprecht, Hermann J. Gruber, Elena E. Pohl, Peter Hinterdorfer 1129-P lat 8:45 am SINGLE MOLECULES IN ATTOLITER DROPLETS: A COMPARISON OF FRET FROM FREE AND CONFINED RNA. Peker Milas , Sheema Rahmanseresht, Ben D. Gamari, Lori S. Goldner 1130-P lat 9:00 am COMBINING ACCURATE FRET AND TRACKING OF SINGLE PROTEIN AND DNA MOLECULES IN LIVE BACTERIA. Anne Plochowietz , Robert Crawford, Louise Aigrain, Marko Sustarsic, Achillefs N. Kapanidis 1131-P lat 9:15 am SINGLE MOLECULE DIAGNOSTIC METHOD TO REVEAL CANCER-RELATED EGFR SIGNALING. Hong-Won Lee , Min Kwon Cha, Kihyuk Shin, Seung-Hyo Lee, Tae-Young Yoon 1132-P lat 9:30 am IMPROVED SINGLE-MOLECULE FORCE SPECTROSCOPY USING MICRO-MACHINED CANTILEVERS. Matthew S. Bull , Hongbin Li, Thomas T. Perkins 1133-P lat 9:45 am FAST SPATIOTEMPORAL CORRELATION SPECTROSCOPY TO DETERMINE PROTEIN LATERAL DIFFUSION LAWS IN LIVE CELL MEMBRANES. Carmine Di Rienzo, Enrico Gratton, Fabio Beltram, Francesco Cardarelli 1134-P lat 10:00 am DNA Y STRUCTURE: A MULTIDIMENSIONAL SINGLE MOLECULE ASSAY. James Inman, Ben Smith, Michael Hall, Robert A. Forties , Michelle D. Wang

1117-S ymp 9:15 am EFFECTS OF TRANSMURAL REGION AND HEART FAILURE ON THE CONTRACTILE PROPERTIES OF HUMAN MYOCARDIUM. Kenneth S. Campbell 1118-S ymp 9:45 am MECHANOSIGNALLING BY CYTOSKELETAL PROTEIN KINASES AND THEIR DISEASE IMPLICATIONS. Mathias Gautel , Ay Lin Kho, Alexander Alexandrovich, Diana Pippig, Hermann Gaub

M O N D A Y

8:15 am –10:15 am , R oom 130/131 Platform Membrane Physical Chemistry II

Co-Chairs Alex Smirnov, North Carolina State University Michael Grabe, University of Pittsburgh 1119-P lat 8:15 am

CURVED LIPID BILAYERS: STRUCTURE, DYNAMICS, PHASE PROPERTIES AND SURFACE ELECTROSTATICS. Antonin Marek, Amir Koolivand, David Song, Maxim A. Voinov, Alex I. Smirnov 1120-P lat 8:30 am MOLECULAR ORIGINS OF THE RIPPLE PHASE. Shachi Katira , Padmini Rangamani, George Oster, Berend Smit 1121-P lat 8:45 am minority affairs travel awardee INFLUENCE OF DETERGENT PROPERTIES ON THE SOLUBILIZATION AND FUNCTION OF MEMBRANE PROTEINS. Ashton T. Brock , Linda Columbus 1122-P lat 9:00 am QUANTITATIVE IMAGING OF THE ELECTROSTATIC FIELD OF A TRANSMEMBRANE PROTEIN AT SUBNANOMETER RESOLUTION BY THE USE OF ATOMIC FORCE MICROSCOPY. Moritz Pfreundschuh 1123-P lat 9:15 am CONTINUOUS FLOW AFM IMAGING REVEALS FLUIDITY AND TIME DEPENDENT INTERACTIONS OF ANTIMICROBIAL DENDRIMER WITH MODEL LIPID MEMBRANES. Tania K. Lind , Paulina Zielinska, Hanna P. Wacklin, Zofia Urbanczyk-Lipkowska, Marité Cárdenas 1124-P lat 9:30 am EXPLORING CONTINUUM MODELS OF ION AND PEPTIDE INTERACTIONS WITH THE MEMBRANE. Naomi R. Latorraca , Keith M. Callenberg, Jon P. Boyle, Michael Grabe 1125-P lat 9:45 am HISTONES AND DNA COMPETE FOR BINDING PHOSPHOINOSITIDES IN BILAYERS. Marta G. Lete , Jesus Sot, Hasna Ahyayauch, Noelia Fernandez-Rivero, Adelina Prado, Felix M. Goni, Alicia Alonso 1126-P lat 10:00 am MULTI-DIMENSIONAL ANALYSIS OF FLUORESCENCE FLUCTUATION SPECTROSCOPY OF LIPID ANCHORED

8:15 am –10:15 am , R oom 303 Platform Micro- and Nanotechnology I

Co-Chairs Young-Wook Jun, University of California, San Francisco Bianxiao Cui, Stanford University 1135-P lat 8:15 am

PROTEINS IN LIVE CELLS REVEAL COMPLEX ORGANIZATION IN THE PLASMA MEMBRANE. Hector H. Huang , Chris R. Rhodes, Katherine N. Alfieri, John T. Groves

REGULATING SPATIOTEMPORAL DYNAMICS OF NOTCH SIGNALING IN LIVE CELLS VIA MAGNETOPLASMONIC NANOPROBES. Daeha Seo, Jiwook Kim, Justin Farlow, Hyunjung Lee, Paul Alivisatos, Jinwoo Cheon, Zev Gartner, Young-wook Jun

67

Biophysical Society 58 th Annual Meeting, San Francisco, California