Program Book

1136-P lat 8:30 am NANOCHANNEL TRAP ARRAYS FOR MONITORING SINGLE MITOCHONDRION BEHAVIOR. Katayoun Zand , Ted Pham, Antonio Davila Jr, Douglas C. Wallace, Peter J. Burke 1137-P lat 8:45 am NANOPLASMONIC OPTOPORATION FOR LARGE-SCALE PRECISION GENE REGULATION IN STEM CELLS. Chi-cheng Fu , Sahba Talebi Fard, Kyuwan Lee, SoonGweon Hong, Luke P. Lee 1138-P lat 9:00 am SINGLE CELL ELECTROPORATION AND DNA DYNAMICS: FROM BULK TO MICRO/NANOLFUIDICS. Pouyan E. Boukany 1139-P lat 9:15 am AT THE NANO-BIO INTERFACE: PROBING LIVE CELLS WITH NANO SENSORS. Ziliang Lin, Wenting Zhao, Lindsey Hanson, Chong Xie, Yi Cui, Bianxiao Cui 1140-P lat 9:30 am SINGLE CELL RESPONSE TO PERIODIC ENVIRONMENTAL STIMULI USING A MICROFLUIDIC BIOREACTOR. Eric M. Johnson Chavarria , Utsav Agrawal, Melikhan Tanyeri, Thomas E. Kuhlman, Charles M. Schroeder 1141-P lat 9:45 am MOTOR-DRIVEN ASSEMBLY OF DYNAMIC, SELF-HEALING LIPID NANOTUBE NETWORKS. George D. Bachand , Nathan F. Bouxsein, Amanda Carroll-Portillo, Marlene Bachand, Darryl Y. Sasaki 1142-P lat 10:00 am FUNCTION AND MOVEMENT OF A DNA ACTUATOR INVESTIGATED BY SINGLE MOLECULE FRET MICROSCOPY. Lasse L. Hildebrandt , Zhao Zhang, Søren Preus, Kurt V. Gothelf, Victoria Birkedal 8:15 am –10:15 am , R oom 304 Platform Protein Structure, Conformation, and Solvent Interactions Co-Chairs Pavan Ghatty, Florida State University Jae Yen Shin, University of California, Berkeley 1143-P lat 8:15 am STRUCTURAL AND FUNCTIONAL STUDIES OF A NOVEL TRANSMEMBRANE ARCHITECTURE OF A FULL-LENGTH MONOSPANNING CYTOCHROME P450. Thomas Tomasiak 1145-P lat 8:45 am IN VIVO ASSEMBLY AND ARRANGEMENT OF THE DNA TRANSLOCASE SPOIIIE DURING CHROMOSOME SEGREGATION AND MEMBRANE FISSION IN B. SUBTILIS. Jae Yen Shin , Cesar Diaz, Javier Lopez, Joerg Schnitzbauer, Kit Pogliano, Carlos Bustamante 1146-P lat 9:00 am ALTERNATIVE CONFORMATIONS OF YEAST ISO-1- CYTOCHROME C: EFFECTS OF A GATEKEEPING RESIDUE ON HEME CREVICE DYNAMICS. Levi J. McClelland , Tung-Chung Mou, Margaret E. Jeakins-Cooley, Melisa M. Cherney, Stephen R. Sprang, Bruce E. Bowler RNA-BINDING SM-LIKE ARCHAEAL PROTEIN. Peter S. Randolph , Kanishk Jain, Cameron Mura 1144-P lat 8:30 am

1147-P lat 9:15 am THE ROLE OFWATER INDYNAMICS OF BIOMACROMOLECULES: A MUTUAL INTERPLAY! Sheila Khodadadi , Hailiang Zhang, Alexei P. Sokolov, Joseph E. Curtis 1148-P lat 9:30 am TRANSIENT ACCESS TO THE PROTEIN INTERIOR: SIMULATION VERSUS NMR. Filip Persson , Bertil Halle 1149-P lat 9:45 am PHYSIOLOGICALLY RELEVANT STRUCTURE OF ALZHEIMER’S RELATED AMYLOID PROTEIN AND THE ROLE OF EMBEDDED WATER IN ITS AMPHIPHILC PORE. Pavan K. Ghatty 1150-P lat 10:00 am STRUCTURAL CHARACTERIZATION OF CADDISFLY SILK WITH SOLID-STATE NMR AND X-RAY DIFFRACTION. J. Bennett Addison , Warner S. Weber, Qiushi Mou, Gregory P. Holland, Jeffery L. Yarger Co-Chairs Heather Pinkett, Northwestern University Gary Rudnick, Yale University 1151-P lat 8:15 am ABC TRANSPORTERS IN H. INFLUENZAE. Heather W. Pinkett 1152-P lat 8:30 am MOVEMENT OF THE NUCLEOTIDE BINDING DOMAINS IN THE RECONSTITUTED ABC TRANSPORTER MSBA DURING THE ATP-HYDROLYSIS CYCLE. Maria E. Zoghbi , Guillermo A. Altenberg 1153-P lat 8:45 am ASYMMETRY AND CONFORMATIONAL CHANGES OF THE E. COLI RIBOSE ABC TRANSPORTER. Satchal K. Erramilli 1154-P lat 9:00 am STRUCTURAL MODEL OF THE HUMAN SODIUM-PHOSPHATE COTRANSPORTERNAPI-II. Maria Cristina Fenollar-Ferrer , Monica Patti, Thomas Knoepfel, Andreas Werner, Ian C. Forster, Lucy R. Forrest 1155-P lat 9:15 am CORRELATING CHARGE MOVEMENTS WITH LOCAL CONFORMATIONAL CHANGES OF A NA-COUPLED COTRANSPORTER. Monica Patti, Ian C. Forster 1156-P lat 9:30 am THE ROLE OF SODIUM SITES IN LEUT CONFORMATIONAL CHANGES. Gary Rudnick , Sotiria Tavoulari, Yuan-Wei Zhang, David DeWitt, Anu Nagarajan, Edwin Rosado, Silvia Ravera, Anna-Elisabeth Kreuder, Lucy R. Forrest, Elizabeth Rhoades 1157-P lat 9:45 am INVESTIGATING THE BACTERIAL GLUTAMATE TRANSPORTER HOMOLOG GLTPH WITH UNNATURAL AMINO ACIDS. Paul J. Focke , Alvin W. Annen, Francis I. Valiyaveetil 1158-P lat 10:00 am SINGLE LIPOSOMES USED TO STUDY THE ACTIVITY OF INDIVIDUAL TRANSPORTERS. Christina Lohr, Andreas Lauge Christensen, Salome Veshaguri , Marijonas Tutkus, Lars Iversen, Gerdi Kemmer, Dana Yaffe, Tina Zollmann, Patricia Curran, Shimon Schuldiner, Robert Tampé, Thomas Pomorski, Joseph Mindell, Dimitrios Stamou 8:15 am –10:15 am , R oom 305 Platform Membrane Pumps, Transporters, and Exchangers I

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Biophysical Society 58 th Annual Meeting, San Francisco, California