BPS Program Book 2014

3776-P os B oard #B504 VOLTAGE GATED LIPID ION CHANNELS. Andreas Blicher, Thomas Heimburg  Ion Channel Regulatory Mechanisms (Boards #B505–#B534) 3777-P os B oard #B505 RECRUITMENT OF G βγ CONTROLS THE BASAL ACTIVITY OF GIRK CHANNELS: CRUCIAL ROLE OF DISTAL C ‐ TERMINUS OF GIRK1. Uri Kahanovitch 3778-P os B oard #B506 REQUIREMENT FOR AN ACTIVATED G PROTEIN α (G α ) SUBUNIT FOR G βγ ACTIVATION OF A PURIFIED MAMMALIAN GIRK1 CHANNEL RECONSTITUTED IN PLANAR LIPID BILAYERS. Edgar Leal-Pinto , Junghoon Ha, Takeharu Kawano, Miao Zhang, Qiong-Yao Tang, Yacob Gomez-Llorente, Jose Chavez, Iban Ubarretxena, Diomedes E. Logothetis 3779-P os B oard #B507 CHOLESTEROL REGULATION OF ATRIAL GIRK CHANNELS. Anna N. Bukiya, Catherine V. Osborn, Peter T. Toth, Gregory Kowalsky, Lia Baki, Myung J. Oh, Irena Levitan, Avia Rosenhouse-Dantsker 3780-P os B oard #B508 IDENTIFICATION OF NOVEL CHOLESTEROL BINDING REGIONS IN THE TRANSMEMBRANE DOMAIN OF KIR2.1. Avia Rosenhouse-Dantsker , Sergei Noskov, Serdar Durdagi, Diomedes E. Logothetis, Irena Levitan 3781-P os B oard #B509 UNIQUE ANIONIC PHOSPHOLIPID BINDING SITE AND GATING MECHANISM IN KIR2.1 INWARD RECTIFIER CHANNELS. Sun Joo Lee , Shizhen Wang, William Borschel, Sarah Heyman, Jacob Gyore, Colin G. Nichols 3782-P os B oard #B510 STRUCTURAL DYNAMICS UNDERLYING PIP2 MODULATION OF KIR CHANNELS REVEALED BY SINGLE MOLECULE FRET. Shizhen Wang , Reza Vafabakhsh, William Borschel, Taekjip Ha, Colin G. Nichols 3783-P os B oard #B511 ACTIVITY OF ROMK CHANNEL IS REGULATED BY PPAR γ IN THE XENOPUS OOCYTES. Siham Ait-Benichou, Ahmed Chraibi 3784-P os B oard #B512 ENHANCEMENT OF CURRENT THROUGH TREK1 TWO PORE DOMAIN CHANNELS BY FLUFENAMIC ACID. Ehab Al-Moubarak , Alistair Mathie 3785-P os B oard #B513 REGULATION OF SK CHANNEL SPATIAL DISTRIBUTION BY TONIC PKA. Krithika Abiraman, Anastasios Tzingounis, George Lykotrafitis 3786-P os B oard #B514 EVIDENCE FOR THE INTERACTION OF ENDOPHILIN 3 WITH THE SK3 CHANNELS IN PC12 CELLS. Malika Janbein , Stephan Grissmer 3787-P os B oard #B515 STRUCTURAL DETERMINANTS OF THE BK CHANNEL γ -SUBUNITS’ MODULATORY POTENCY. Qin Li , Yingxin Li, Ha Rim Kwak, Jiusheng Yan

3788-P os B oard #B516 A POINT MUTATION THAT IMPAIRS THE OMEGA-3 FATTY ACID SENSITIVITY OF HUMAN SLO1 BK CHANNELS. Toshinori Hoshi , Rong Xu, Shangwei Hou, Stefan H. Heinemann, B oard #B517 CALCIUM AND PIP2 INTERPLAY REGULATES BK CHANNEL ACTIVITY VIA THE RCK1 GATING RING. Qiong-Yao Tang, Zhe Zhang, Xuan-Yu Meng, Meng Cui, Diomedes E. Logothetis 3790-P os B oard #B518 PIP2-CHANNEL INTERACTION AS A CRITICAL ELEMENT IN REGULATION OF SK CHANNEL ACTIVITY. Miao Zhang , Meng Cui, Xuan-Yu Meng, Ji-Fang Zhang, Diomedes E. Logothetis 3791-P os B oard #B519 DYNAMIC PIP2-IKS INTERACTIONS MEDIATE CARDIAC RATE ADAPTATION. Mark A. Zaydman , Yang Li, Zachary Beller, Dick Wu, Haoyang Rong, Jonathan R. Silva, Kelli Delaloye, Jingyi Shi, Ira Cohen, Jianmin Cui 3792-P os B oard #B520 ANGIOTENSIN II MODULATES I KS BY MULTIPLE MECHANISMS WITH VARYING OUTCOMES. Yuhong Wang, Min Jiang, Mei Zhang, Dona Occhipinti, Tseng Gea-Ny 3793-P os B oard #B521 NOVEL ROLE FOR KCHIP2 AS A TRANSCRIPTIONAL REGULATOR OF CARDIAC GENES. Drew M. Nassal , Haiyan Liu, Xiaoping Wan, Eckhard Ficker, Isabelle Deschenes 3794-P os B oard #B522 BIOCHEMICAL ASSAYS OF CAM AND PIP2 INTERACTIONS WITH KCNQ CHANNEL DOMAINS. Crystal R. Archer , Pamela A. Reed, Mark S. Shapiro 3795-P os B oard #B523 USE OF A VOLTAGE-SENSITIVE PHOSPHATASE HIGHLIGHTS TWO PIP2-BINDING SITES IN THE C-TERMINUS OF KCNQ3 CHANNELS. Frank S. Choveau , Mark S. Shapiro 3796-P os B oard #B524 PHOSPHOINOSITIDE REGULATION OF THE MECHANOSENSITIVE PIEZO CHANNELS. Istvan Borbiro , Doreen Badheka, Tibor Rohacs 3797-P os B oard #B525 LINOLENIC AND LINOLEIC ACID INDUCE THE OPENING OF CONNEXIN 43, 46 AND 50 HEMICHANNEL IN HUMAN HELA CELLS. Vania A. Figueroa, Mauricio A. Retamal 3798-P os B oard #B526 ENHANCING THE ATPASE ACTIVITY OF THE CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR CFTR IN LIVE CELLS REDUCES CHLORIDE FLUX. Anna Seelig , Matthias Zwick 3799-P os B oard #B527 MECHANISM OF CLCA1-MEDIATED CACC ACTIVATION IN CHRONIC LUNG DISEASES. Zeynep Yurtsever , Monica Sala-Rabanal, Colin G. Nichols, Tom J. Brett 3800-P os B oard #B528 THE MAGUK SCAFFOLDING PROTEIN CASK REGULATES TMEM16A CHANNEL FUNCTION BY PHOSPHORYLATION. Kuai Yu , Jinqiu Zhu, Yuanyuan Cui, H. Criss Hartzell Yutao Tian 3789-P os

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Biophysical Society 58 th Annual Meeting, San Francisco, California