BPS Program Book 2014

725-P os B oard #B480 minority affairs travel awardee KCNE1 SEPARATES THE MAIN VOLTAGE SENSOR MOVEMENT AND CHANNEL OPENING IN KCNQ1/KCNE1 CHANNELS. Rene Barro-Soria , Santiago Rebolledo, Sara I. Liin, Marta E. Perez, Kevin Sampson, Robert S. Kass, H Peter Larsson 726-P os B oard #B481 SPECIFICTARGETING OF KV7.1/KCNE1 CHANNEL COMPLEXES. Eva Wrobel , Nathalie Strutz-Seebohm, Eric Schulze-Bahr, Guiscard Seebohm 727-P os B oard #B482 AN ACTIVATOR BINDING SITE IN THE GATING CHARGE PATHWAY OF KCNQ2 CHANNEL. Ping Li, Zhuxi Chen, Huaiyu Yang , Zhaobing Gao, Hualiang Jiang, Min Li 728-P os B oard #B483 UNNATURAL AMINO ACID MUTAGENESIS REVEALS THE CRITICAL ROLE OF HYDROGEN BONDING FOR BINDING OF RETIGABINE IN THE PORE OF KCNQ CHANNELS. Stephan A. Pless , Michael Yau, Jason D. Galpin, Christopher A. Ahern, Harley T. Kurata 729-P os B oard #B484 PHARMACOLOGICAL PROPERTIES OF HOMOMERIC KV7.4, KV7.5 AND HETEROMERIC KV7.4/7.5 CHANNELS: EFFECTS OF ICA069673 AND ML213. Lyubov I. Brueggemann , Jennifer M. Haick, Kenneth L. Byron 730-P os B oard #B485 A MODEL OF HUMAN POTASSIUM CHANNEL KCNQ1 MODULATION BY ACCESSORY PROTEIN KCNE3. Brett M. Kroncke , Wade Van Horn, Carlos Vanoye, David Nannemann, Jens Meiler, Charles Sanders 731-P os B oard #B486 KCNE1 MODULATES THE SENSITIVITY OF KV7.1 TO POLYUNSATURATED FATTY ACIDS. Sara I. Liin , Nicole Schmitt, Johan Larsson, Frida Starck Härlin, Bo H. Bentzen, H. Peter Larsson, Fredrik Elinder  Anion Channels and Transporters (Boards #B487–#B515) 732-P os B oard #B487 CALCIUM-CALMODULIN DOES NOT ALTER THE ANION PERMEABILITY OF THE TMEM16A CALCIUM-ACTIVATED CHLORIDE CHANNEL. Yawei Yu, Ai-Seon Kuan , Tsung-Yu Chen 733-P os B oard #B488 SERINE 550 IS INVOLVED IN THE REGULATION OF MOUSE TMEM16A-CACCS BY CAMKII. Normand Leblanc , Ramon J. Ayon, Michael Wiwchar, Jaime Callilung, Cherie A. Singer, Iain A. Greenwood 734-P os B oard #B489 INHIBITORY ROLE OF PIP2 ON CALCIUM-ACTIVATED CHLORIDE CHANNEL ACTIVITY. Harry A.T. Pritchard , Anthony P. Albert, Normand Leblanc, Iain A. Greenwood 735-P os B oard #B490 PROBING THE TRANSMEMBRANE TOPOLOGY OF TMEM16A(A)/ANOCTAMIN-1 BY CYSTEINE SCANNING MUTAGENESIS. Gunther Schmalzing , Silvia Detro-Dassen, Fritz Markwardt

736-P os B oard #B491 ELECTROPHYSIOLOGICAL CHARACTERISATION OF TMEM16A CURRENTS IN ESOPHAGEAL SQUAMOUS CELL CARCINOMA CELLS. Mariana Oana Popa , Hedaythul Choudhury, Christopher Rothwell, Larry Alex Gaither, Martin Gosling, Pamela Tranter 737-P os B oard #B492 ELECTROPHYSIOLOGICAL PROPERTIES OF TMEM16A CALCIUM-ACTIVATED CHLORIDE CHANNELS. Ai-Seon Kuan, Yu-Li Ni , Tsung-Yu Chen 738-P os B oard #B493 MONITORING SUBSTRATE-DRIVEN STRUCTURAL CHANGES IN A CLC CHLORIDE-PROTON ANTIPORTER WITH DOUBLE ELECTRON-ELECTRON RESONANCE SPECTROSCOPY. Ricky C. Cheng , Philip Chang, Christina Fenollar-Ferrer, Richard A. Stein, Kristin Trone, Lucy R. Forrest, Hassane S. Mchaourab, Merritt C. Maduke 739-P os B oard #B494 TESTINGTHE LIMITS OF STOICHIOMETRIC EXCHANGE IN A CLC-TYPETRANSPORTER. Daniel Basilio , Allison Vera, Alessio Accardi 740-P os B oard #B495 CONFORMATIONAL CHANGES REQUIRED FOR CHLORIDE ION PERMEATION IN THE CLC-EC1 EXCHANGER. Yanyan Xu , Chungwen Liang, Daniel Basilio, Alessio Accardi, Simon Bernèche 741-P os B oard #B496 TRANSPORT MECHANISM IN CLC H + /C - EXCHANGERS. Chungwen Liang , YanYan Xu, Simon Bernèche 742-P os B oard #B497 SELECTIVITY IN CLC-F FLUORIDE TRANSPORTERS: A SEARCH FOR THE KEY PLAYERS. Ashley E. Brammer , Randy B. Stockbridge, Christopher Miller 743-P os B oard #B498 A SINGLE POINT MUTATION REVEALS GATING OF THE HUMAN ENDOSOMAL CL - /H + ANTIPORTER CLC-5. Giovanni Zifarelli , Silvia De Stefano, Michael Pusch 744-P os B oard #B499 THE AMINO TERMINUS CONTROLS SORTING AND VOLTAGE DEPENDENCE OF CLC 3. Raul E. Guzman Castro , Erick Miranda Laferte, Gabriel Stölting, Christoph Fahlke 745-P os B oard #B500 THE CLC-3 N-TERMINUS MODULATES MEMBRANE TRAFFICKING AND TRANSPORT ACTIVITY. Jeffrey Rohrbough , Hong-Ngan Nguyen, Fred S. Lamb 746-P os B oard #B501 ROLES OF CYTOPLASMIC IONS IN LYSOSOMAL ACIDIFICATION. Pascal Courville , Joseph A. Mindell 747-P os B oard #B502 INVOLVEMENT OF BARTTIN SUBUNIT IN PHARMACOLOGICAL POTENTIATION OF CLC-K CHANNELS EXPRESSED IN XENOPUS OOCYTES. Antonella Gradogna , Antonella Liantonio, Paola Imbrici, Diana Conte Camerino, Michael Pusch 748-P os B oard #B503 REDUCED CURRENT DENSITY AND SURFACE EXPRESSION OF A CLCN1 MUTATION CAUSING DOMINANT OR RECESSIVE MYOTONIA IN COSTA RICA. Michele Fiore , Raul Estevez, Héctor Gaitán-Peñas, Mauricio Ezpinoza, Melissa Vásquez, Rebeca Vindas, Michael Pusch, Fernando Morales

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Biophysical Society 58 th Annual Meeting, San Francisco, California