BPS Program Book 2014

Ligand-gated Channels I (Boards #B516-#B544)

749-P os B oard #B504 ROLE OF CANDIDATE COUNTERIONS IN CLATHRIN COATED VESICLE ACIDIFICATION. Mary Weston 750-P os B oard #B505 CHARACTERIZING ATP PERMEATION THROUGH THE VOLTAGE-DEPENDENT ANION CHANNEL VDAC. Om P. Choudhary , Aviv Paz, Joshua Adelman, Jacques-Philippe Colletier, Jeff Abramson, Michael Grabe 751-P os B oard #B506 GENOMICS-AIDED STRUCTURAL MODELING OF AN ANTIPARALLEL HOMODIMERIC FLUORIDE CHANNEL. Eugene J. Palovcak , Lucie Delemotte, Michael L. Klein, Vincenzo Carnevale 752-P os B oard #B507 MOUSE CFTR EXHIBITS MULTIPLE CHARACTERISTIC PROBING STRUCTURE AND CONFORMATIONAL CHANGES IN THE EXTRACELLULAR LOOPS OF CFTR. Daniel T. Infield , Guiying Cui, Chris Kuang, Nael A. McCarty 754-P os B oard #B509 INTERACTION OF THE ISOLATED NUCLEOTIDE BINDING DOMAINS OF CFTR CHANNELS. Mark O. Palmier, Silvia G. Bompadre 755-P os B oard #B510 NON-EQUILIBRIUM GATING OF CFTR REVEALED BY NITRATE AS CHARGE CARRIERS. Jiunn-Tyng Yeh , Han-I Yeh, Tzyh-Chang Hwang 756-P os B oard #B511 CHLORIDE TRANSPORT INHIBITION CAUSES CALCIUM-DEPENDENT ARRHYTHMIC ACTIVITY IN ISOPROTERENOL-TREATED RABBIT CARDIOMYOCYTES. Shane P. Antrobus, Blake Nichols, Don M. Bers, Julie Bossuyt, John A. Payne 757-P os B oard #B512 ANION PERMEATION THROUGH EXCITATORY AMINO ACID TRANSPORTERS. Jan-Philipp Machtens , Christine Lansche, Ariane Leinenweber, Petra Kilian, Birgit Begemann, Ulrich Zachariae, David Ewers, Bert L. de Groot, Rodolfo Briones, Christoph Fahlke 758-P os B oard #B513 INVESTIGATING THE STRUCTURE-FUNCTION RELATION- SHIP OF THE PHOSPHATE-SELECTIVE CHANNEL OPRP. Niraj Modi , Iván Bárcena-Uribarri, Manjeet Bains, Roland Benz, Robert E. W. Hancock, Ulrich Kleinekathöfer 759-P os B oard #B514 DESCRIPTION OF THE STRUCTURAL DETERMINANTS OF THE HPEPT1-LIGAND INTERACTIONS. Claire Colas , Avner Schlessinger 760-P os B oard #B515 DYNAMICS OF CA 2+ -DEPENDENT REGULATION OF THE CARDIAC NA + /CA 2+ EXCHANGER. Lulu Chu , Liron Boyman, George S.B. Williams, Joseph L. Greenstein, Raimond L. Winslow, W. J. Lederer, Brian Hagen DIFFERENCES FROM HUMAN CFTR. Guiying Cui , Christopher Kuang, Chengyu Z. Prince, Nael A. McCarty 753-P os B oard #B508

761-P os B oard #B516 A HUMAN MUTATION IN THE M4 HELIX OF GLUN2A ACCELERATES FORWARD GATING TRANSITIONS IN NMDA RECEPTORS. Kevin K. Ogden , Hongjie Yuan, Kasper B. Hansen, Jing Zhang, Aladair J. Gibb, Stephen F. Traynelis 762-P os B oard #B517 FUNCTIONAL CONSEQUENCES OF CYSTEINE MUTATIONS AT THE KAINATE RECEPTOR DIMER INTERFACE. Bryan A. Daniels , Mark RP Aurousseau, Maria Musgaard, George B. Dawe, Philip C. Biggin, Derek Bowie 763-P os B oard #B518 RECOVERY OF AMPA RECEPTOR GLUA1 IS MODULATE BY TARPS. Wei Zhang , James Howe 764-P os B oard #B519 MECHANISM OF MODULATION OF AMPA RECEPTORS BY STARGAZIN. Anna L. Carbone , Andrew J. Plested 765-P os B oard #B520 CHARACTERIZATION OF LIGHT-CONTROLLABLE POLYAMINE TOXIN INHIBITORS OF IONOTROPIC GLUTAMATE RECEPTORS. Mette H. Poulsen , Niels G. Nørager, Martin Sumser, Dirk Trauner, Kristian Strømgaard 766-P os B oard #B521 CALCIUM FLUX THROUGH AVGLUR1: A GLUTAMATE RECEPTOR WITH A POTASSIUM CHANNEL SELECTIVITY SEQUENCE. Mark Mayer , Suvendu Lomash 767-P os B oard #B522 ROLE OF AMINO-TERMINAL DOMAIN IN THE ASSEMBLY MECHANISM OF KAINATE-SUBTYPE GLUTAMATE RECEPTOR ION CHANNELS. Sagar Chittori , Janesh Kumar, Suvendu Lomash, Huaying Zhao, Peter Schuck, Mark L. Mayer 768-P os B oard #B523 INVESTIGATING HIGH AFFINITY PROTEIN SELF-ASSOCIATION BY FLUORESCENCE OPTICAL SEDIMENTATION VELOCITY ANALYTICAL ULTRACENTRIFUGATION. Suvendu Lomash , Huaying Zhao, Carla Glasser, Mark L. Mayer, Peter Schuck 769-P os B oard #B524 FöRSTER RESONANCE ENERGY TRANSFER (FRET) ANALYSIS OF DUAL CFP/YFP LABELED AMPA RECEPTORS REVEALS STRUCTURAL REARRANGEMENT WITHIN THE C-TERMINAL DOMAIN DURING RECEPTOR ACTIVATION. Linda Zachariassen , Mila Katchan, Andrew Plested, Darryl S. Pickering, Anders S. Kristensen 770-P os B oard #B525 A COMPUTATIONAL STUDY OF LIGAND BINDING IN CHEMOSENSORY IONOTROPIC GLUTAMATE RECEPTORS. Benoite Bargeton , Matteo Dal Peraro, Richard Benton 771-P os B oard #B526 CHARACTERIZING THE ENERGETIC STATES OF A GLUTAMATE RECEPTOR USING UMBRELLA SAMPLING AND MICROSECOND MOLECULAR DYNAMICS SIMULATIONS. Michael Yonkunas , Maiti Buddhadev, Maria Kurnikova

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Biophysical Society 58 th Annual Meeting, San Francisco, California