BPS2024 Full Program & Abstracts

Symposium Black in Biophysics 10:45 am - 12:45 pm, Room 103AB

125-Plat 1 2:15 pm DYNAMIC INTERDOMAIN INTERACTIONS IN OLIGOMERIC AND HIGHER ORDER ASSEMBLIES CAN MODULATE THE INTRINSIC STRUCTURAL FEATURES OF HUNTINGTIN EXON 1. Priyesh Mohanty , Tien M. Phan, 12:30 pm MECHANISM OF MASTER COREPRESSOR INACTIVATION THROUGH MULTIVALENT SLIM-INDUCED POLYMERIZATION. Matthias Wilmanns 127-FlashTalk 12:35 pm HOW TO EVICT HP1 FROM H3: USE YOUR BIOPHYSICAL-FORCE TOOLBOX AND TRY A COMPLEX SALT BRIDGE. George V. Papamokos , Efthimios Kaxiras 128-FlashTalk 12:40 pm DESIGNING DISORDERED PROTEINS FOR DESICCATION PROTECTION. Kara Hunter Platform Ion Channel Regulatory Mechanisms 10:45 am - 12:45 pm, Room 201AB Co-Chairs Sandipan Chowdhury, University of Iowa, USA Susy Kohout, Rowan University, USA 129-Plat 10:45 am ACTIVATION OF THE PROTON CHANNEL OTOP1 BY AMMONIUM CHLO RIDE AS A MECHANISM FOR TASTE TRANSDUCTION. Ziyu Liang , Emily 11:00 am IMPACT OF S1 HYDROPHOBIC RESIDUES ON VOLTAGE SENSING. Vam seedhar Rayaprolu, Heini Miettinen-Granger, William Baker, Matthew Fisher, Gwendolyn Mueller, William O. Rankin, J. Jack Kelly, William J. Ratzan, Lee Min Leong, Joshua A. Davisson, Bradley J. Baker, Susy C. Kohout 131-Plat 11:15 am ELECTROCHEMICAL LINKAGE IN A SPERM-SPECIFIC HCN TRANSPORTER. Kamalendu Pal , Sandipan Chowdhury 132-Plat 11:30 am CRYO-ELECTRON MICROSCOPY STRUCTURE OF HUMAN KIR2.1 POTAS SIUM CHANNEL BOUND TO THE ACTIVATOR PIP 2 REVEALS ITS GATING MECHANISM. Carlos A.H. Fernandes , Dania Zuniga, Rafael F. Veloso, Andreas Zoumpoulakis, Renaud Wagner, Catherine Venien-Bryan 133-Plat 11:45 am AN ENGINEERED POTASSIUM CHANNEL FOR THERMOGENETICS. Anna Moroni , Chiara Mercutio, Guido Rey, Bianca Piermaria, Roberta Leone, Alberto Russo, Monica Beltrame, Raffaella Tonini, andrea saponaro, Gerhard Thiel 134-Plat 12:00 pm INHIBITION OF ION CHANNEL FUNCTIONAL EXPRESSION BY TARGETED RECRUITMENT OF NEDD4-2 WITH DIVALENT NANOBODIES. Travis J. Morgenstern, Arden Darko-Boateng , Sri Karthika Shanmugam, Xinle Zhou, Papiya Choudhury, Meera Desai, Talya A. Givoni, Robert S. Kass, Henry M. Colecraft 135-Plat 12:15 pm CRYO-EM STRUCTURES OF K CA 2.2 CHANNELS REVEAL THE CONFORMA TIONAL CHANGES IN THE SELECTIVITY FILTER INDUCED BY AN INHIBI TOR. Young-Woo Nam, Mario Tringides, Dohyun Im, Hai M. Nguyen, Yan Liu, Chih-Chia Su, Meng Cui, Heike Wulff, Edward W. Yu, Miao Zhang Jeetain Mittal 126-FlashTalk R. Liman 130-Plat

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Co-chairs Jerelle Joseph, Princeton University, USA Aaron Streets, University of California, Berkeley, USA 116-Symp 10:45 am EXPLORING THE STRUCTURAL BASIS OF ANTIBODY-ENVELOPE INTERAC TIONS AND THE SIGNIFICANCE OF GLYCAN ARRAYS IN EPITOPE RECOG NITION. Christopher O. Barnes , Joshua J. Carter, Mark E. Berlaga 117-Symp 11:15 am LONG NONCODING RNAS: STRUCTURE AND FUNCTION. Alisha Jones 118-Symp 11:45 am REVEALING PATHWAYS OF RIBOSOME ASSEMBLY AND VIRAL RNA PRO CESSING WITH TIME-RESOLVED FLUORESCENCE. Sharonda LeBlanc , Lewis Alex Rolband, Kenya Gordon, Ben Clark, Jose Castaneda, Irene Silvernail, Andi Morgan, Patil Smruti, Meredith Frazier, Zoe Wright, Isha Wilson, Robin Evans Stanley No Abstract 12:15 pm OF UBIQUITIN, ION CHANNELS, AND DISEASES. Henry M. Colecraft Platform Intrinsically Disordered Proteins I 10:45 am - 12:45 pm, Room 113AB Co-Chairs Jhullian Alston, Boston Children’s Hospital, USA Melody Di Bona, Memorial Sloan Kettering Cancer Center, USA 119-Plat 10:45 am ATOMISTIC ENSEMBLE RESOLUTION OF AN INTRINSICALLY DISORDERED PEPTIDE WHICH UNDERGOES PROLINE CIS/TRANS ISOMERISATION. Al ice J. Pettitt , Vaibhav K. Shukla, Lydia S. Newton, Angelo M. Figueiredo, Stephen McCarthy, Alethea B. Tabor, Gabriella T. Heller, Chris D. Lorenz, D Flemming Hansen 120-Plat 11:00 am ELUCIDATING THE COMPLEXATION BETWEEN HIGHLY CHARGED DISORDERED PROTEINS WITH SINGLE-MOLECULE FRET (SMFRET) AND INTEGRATIVE DATA ANALYSIS. Aritra Chowdhury , Alessandro Borgia, Souradeep Ghosh, Andrea Sottini, Soumik Mitra, Rohan S. Eapen, Mad eleine B. Borgia, Tianjin Yang, Nicola Galvanetto, Miloš T. Ivanović, Paweł Łukijańczuk, Ruijing Zhu, Daniel Nettels, Arindam Kundagrami, Benjamin Schuler 121-Plat 11:15 am PHOSPHORYLATION MODULATES ESTROGEN RECEPTOR DISORDER BY ALTERING HYDROPHOBIC CLUSTERING OF RESIDUAL STRUCTURES. Sichun Yang 122-Plat 11:30 am UNEARTHING SRSF1’S NOVEL FUNCTION IN BINDING AND UNFOLDING OF RNA G-QUADRUPLEXES. Jun Zhang 123-Plat 11:45 am CONSERVED MOLECULAR RECOGNITION BY AN INTRINSICALLY DISOR DERED REGION IN THE ABSENCE OF SEQUENCE CONSERVATION. Jhul lian J. Alston , Andrea Soranno, Alex S. Holehouse 124-Plat 12:00 pm Travel Award Winner IMPACT OF CROWDING ON CONFORMATIONS AND INTERACTIONS OF THE SARS-COV-2 NUCLEOCAPSID PROTEIN AND RNA. Madison Stringer , Jasmine Cubuk, Jeremias Incicco, Debjit Roy, Kathleen B. Hall, Melissa D. Stuchell-Brereton, Andrea Soranno

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