BPS2025 Full Program

Protein Structure and Conformation II (Boards B1 - B32)

1007-Pos Board B14 CORRELATED CRYO-EM STRUCTURES OF AMYLOID-Β IN THE RETINA AND BRAIN OF AN ALZHEIMER’S DISEASE MODEL. Do Hyun Bae , Dong sun Shin, Hyeyeon Jeon, Eun Sung Kang, Yong Ho Kim 1008-Pos Board B15 OXIDATIVE STRESS INDUCED CONFORMATIONAL AND STRUCTURAL CHANGES IN PROTEINS. Debdip Brahma 1009-Pos Board B16 INVESTIGATING SEQUENCE VARIABILITY AND STRUCTURAL DETER MINANTS OF PRION PROTEIN MISFOLDING. Alessandro Cembran , Aliciarose John, David Kemper, Pedro Fernandez-Funez 1010-Pos Board B17 UNDERSTANDING THE FOLDING MECHANISM OF THE +3 1 TREFOIL KNOT IN MTT SA . Tiange Tao 1011-Pos Board B18 CHARACTERIZING CU(I)- AND CU(II)-AMYLOID BETA PEPTIDE COM PLEXES: A COMPUTATIONAL AND EXPERIMENTAL APPROACH. Velia Minicozzi , Stefania Alleva, Alessia Muroni, Emiliano De Santis, Richard Bean, Francesco Stellato 1012-Pos Board B19 PURSUIT OF THE ELUSIVE DISULFIDE CROSSLINK IN OXIDIZED GAMMAS CRYSTALLIN FROM THE EYE LENS. Kirsten Lampi , Constance Kraay, Kate Halverson-Kolkind, David Thorn, Eugene Shakhnovich, Larry David 1013-Pos Board B20 CHARACTERIZING INTRINSICALLY DISORDERED DOMAIN DYNAMICS OF Α-SYNUCLEIN USING SITE-DIRECTED SPIN LABELING. Qingya Zhang 1014-Pos Board B21 ENTROPY-DRIVEN PROTEIN CONFORMATIONAL CHANGES MEDIATED BY WATER NETWORK. Junlang Liu , Yichong Wang, Dianzhuo Wang, Sourav Chowdhury, Kit Parker, Eugene Shakhnovich 1015-Pos Board B22 INTRA-RESIDUE HYDROGEN BONDS IN CYSTEINE, SERINE AND THREO NINE RESIDUES IN PROTEINS: STRUCTURAL BIOINFORMATICS AND QUANTUM CHEMICAL CALCULATIONS. Prathvi Singh , Venkatnarayanan Ramanathan, Ramasubbu Sankararamakrishnan 1016-Pos Board B23 MOLECULAR LEVEL INFORMATION FROM LOW RESOLUTION DATA: AP PLYING SAXS, MD AND NOVEL MODELLING TECHNIQUES TO ELUCIDATE IGG2 F(AB)2 STRUCTURAL ENSEMBLES. Cameron L. Brown 1017-Pos Board B24 FROM PREDICTION TO PROOF: HIGH THROUGHPUT VALIDATION OF ALPHAFOLD-GENERATED STRUCTURES BY CIRCULAR DICHROISM SPEC TROSCOPY. József Kardos , Frank Wien, Éva Moussong, Nikoletta Murvai, Márton P. Nyiri, Tamás Molnár, Frederic Jamme, András Micsonai 1018-Pos Board B25 EXPERIMENTAL SETUP UPDATE AT THE LIFE SCIENCES X-RAY SCATTER ING BEAMLINE (LIX). Shirish N. Chodankar 1019-Pos Board B26 CHARACTERIZATION OF A SERINE DEPENDENT INTEIN FOR PROTEIN SEGMENTAL LABELING. Sam W. Marchant , Galia T. Debelouchina 1020-Pos Board B27 NOVEL TOPOLOGICAL METRICS OF BIOPOLYMER STRUCTURE AND FUNCTION. Eleni Panagiotou 1021-Pos Board B28 EVOLUTIONARY CLASSIFICATION OF PROTEIN DOMAINS: UNVEILING PROTEIN FUNCTIONS AND ADVANCING DRUG DISCOVERY. Kirill E. Medvedev , Nick V. Grishin

M O N D A Y

994-Pos Board B1 EXPLORING REDOX AND ELECTRON TRANSFER MECHANISMS IN AMICYANIN: INSIGHTS FOR CATALYST DESIGN AND FUEL CELL EFFI CIENCY. Narayanasami Sukumar , Victor L. Davidson, Sahana L. Sukumar, Divya Prakash 995-Pos Board B2 STRUCTURAL AND MOLECULAR BASIS OF HEME CAPTURE BY PATHO GENIC CORYNEBACTERIUM DIPHTHERIAE . Jordan Ford , Andrew Goring, Brendan J. Mahoney, Megan Chen, Michael R. Sawaya, Duilio Cascio, Robert T. Clubb 996-Pos Board B3 INTERMOLECULAR HYDROGEN BOND NETWORK IN A BACTERIAL VIRU LENCE FACTOR AS A KEY DETERMINANT OF THERMODYNAMIC STABIL ITY. Christoph Wiedemann , Jean-Martin Harder, Sabine Häfner, Jacob Whittaker, Philip Wurm, Jens Woehnert, Albert Guskov, Ute A. Hellmich 997-Pos Board B4 PEG-MCHERRY INTERACTIONS BEYOND CLASSICAL MACROMOLECULAR CROWDING. Liam Haas-Neill, Khalil Joron, Eitan Lerner, Sarah Rauscher 998-Pos Board B5 BIOCHEMICAL CHARACTERIZATION OF A FUNDAMENTALLY CONSERVED STRUCTURE THE SYNAPTONEMAL COMPLEX. Kaylee A. Patterson 999-Pos Board B6 ROLE OF DISORDERED REGIONS IN DYNAMIN-RELATED PROTEIN 1 STRUCTURE AND FUNCTION. Anelise Hutson 1000-Pos Board B7 MODIFICATION OF THE CARBOXYL-TERMINUS OF THE PLASMODIUM FALCIPARUM CIRCUMSPOROZOITE PROTEIN INDUCES CONFORMATION AL CHANGES . Kristine M. Jones , Sofia Nakuchima, Karine Reiter, Martin Burkhardt, Apostolos Gittis, Lynn Lambert, Solomon Conteh, Guofeng Zhang, Jonathan Renn, Richard D. Leapman, Patrick E. Duffy, Albert J. Jin, David L. Narum 1001-Pos Board B8 CHAPERONES COOPERATIVELY ORCHESTRATE THE SHAPING OF BETA PROPELLER STRUCTURE. Seyeon Lim , Daniel Gestaut, Soung-Hun Roh, Judith Frydman 1002-Pos Board B9 THE ROLE OF GROES/EL CHAPERONINS IN THE ENZYMATIC ACTIVITY OF A PHOTOACTIVABLE ADENYLATE CYCLASE. Elek Telek , Emoke Bodis, Zsuzsanna Lukacs, Andras Kengyel, Andras Lukacs, Ildiko Pecsi 1003-Pos Board B10 ASPARAGINE TO ASPARTATE DEAMIDATION DOES NOT DISRUPT ΓD CRYSTALLIN STABILITY AND STRUCTURE. Jeremy J. Gonzalez , Alex Guse man, Darian Yang, Angela M. Gronenborn 1004-Pos Board B11 FAST PROBING AMYLOID POLYMORPHISM VIA NANOPORE SENSOR. Lijian Zhan , Andela Vracar 1005-Pos Board B12 PROBING THE INTERACTION OF DNAJB1 WITH HUNTINGTIN AND ALPHA-SYNUCLEIN FIBRILS. Dhanya Sathiavals Reselammal 1006-Pos Board B13 HOW IMPORTANT IS THE AMYLOID CORE FOR INTRINSICALLY DISOR DERED REGION DYNAMICS AND CHAPERONE BINDING? Gauri Velloor

78