BPS2025 Full Program

Intracellular Organelle Dynamics (Boards B309 - B319)

1291-Pos Board B298 PMCA1: AN OVERLOOKED REGULATOR OF CALCIUM HOMEOSTASIS IN THE HEART. Rui Zhang , Seyi Elijah Elasoru, Haruko Masumiya, Raven Norris, Sabine Lotteau, Joice T. Gavali, Seho Kim, Jennifer Ding, Liang Li, Gary E. Shull, Kenneth D. Philipson, Michela Ottolia, Joshua I. Goldhaber 1292-Pos Board B299 EARLY AND LATE EFFECTS OF A SNAKE VENOM LYS49 PLA2-LIKE MYO TOXIN ON RAT LOADED LIVING MYOCARDIAL SLICES. Wilson Agyapong, Natalie Weber, Florian J.G. Waleczek, Susanne Neumueller, Marlen Moellmann, Theresia Kraft, Julián Fernández, José M. Gutiérrez, Bruno Lomonte, Thomas Thum, Alfredo López Dávila 1293-Pos Board B300 MECHANISTIC LINK BETWEEN DYNAMICAL INSTABILITY, QT INTERVAL VARIABILITY, AND ARRHYTHMIA RISK. Daisuke Sato , Bence Hegyi, Crys tal M. Ripplinger, Donald M. Bers 1294-Pos Board B301 RYANODINE RECEPTOR CA 2+ LEAK SIGNALLING REMAINS FUNCTIONALLY INTACT AND REGULATES ENERGY EXPENDITURE IN SEDENTARY, AGED MOUSE MUSCLE. Aldo Meizoso Huesca, Rocky Choi, Cedric Lamboley, Nicole A. Beard, Daniel Blackmore, Bradley S. Launikonis 1295-Pos Board B302 CONTRACTION FAILURE ASSOCIATED TO RYR2 CALCIUM LEAK IN ENGI NEERED HEART TISSUES FROM DUCHENNE MUSCULAR DYSTROPHY PA TIENTS. Lucrezia Giammarino, Marianna Langione, Alessandra Fornaro, Olivier F. Cazorla, Alain Lacampagne, David L. Mack, Cecilia Ferrantini, Raffaele Coppini, Albano C. Meli, J. Manuel Pioner 1296-Pos Board B303 RIGHT VENTRICULAR CARDIOMYOCYTE EXCITATION-CONTRACTION COUPLING DEFECTS IN A MOUSE MODEL OF TYPE 3 PULMONARY HY PERTENSION. Andrew J. Behrmann , Scott Roselli, Arooj Shahid, Charles E. Norton III, Timothy L. Domeier 1297-Pos Board B304 POTENTIAL MECHANISM FOR LOCAL CA 2+ -FREQUENCY RESPONSE DIF FERENCE BETWEEN RIGHT AND LEFT ATRIAL MYOCYTES. Joon-Chul Kim, Phuong Kim Luong, Hieu T. Huynh, Tran Nyguet Trinh, Sun-Hee Woo 1298-Pos Board B305 MITOCHONDRIAL INTER-MEMBRANE SPACE IS A DISTINCT SUBCELLU LAR CA 2+ COMPARTMENT. Radmila Terentyeva , Andriy E. Belevych, Fru zsina Perger, Roland Veress, Gyorgy Csordas, Zuzana Nichtova, Shanna Hamilton, Dmitry A. Terentyev 1299-Pos Board B306 QUANTITATIVE ANALYSIS OF SEX-DEPENDENT MECHANISMS OF CARDIOMYOCYTE DYSFUNCTION IN TWO TRANSLATIONAL MURINE MODELS OF HFPEF . Mohamadamin Forouzandehmehr, Ishaan Dhaliwal, Bence Hegyi, Donald Bers, Stefano Morotti 1300-Pos Board B307 A COMPUTATIONAL MODEL OF OXIDATIVE STRESS IN A HUMAN VEN TRICULAR MYOCYTE. Hannah Zukowski , Gonzalo Hernandez Hernan dez, Pei-Chi Yang, Timothy J. Lewis, Colleen E. Clancy 1301-Pos Board B308 CARDIAC GLYCOSIDE-DRIVEN POSITIVE INOTROPY REQUIRES ALLOSTE RIC INACTIVATION OF THE SODIUM-CALCIUM EXCHANGER BY INTRA CELLULAR SODIUM. Kyle Scranton , Scott John, Rui Zhang, Joshua I. Goldhaber, Riccardo Olcese, Michela Ottolia

M O N D A Y

1302-Pos Board B309 MEASURING ER-MITOCHONDRIAL CONTACTS (ERMC) IN LIVE CELLS. Vic tor H. Sanchez-Vazquez, Mateus P. Mori, Janine H. Santos, Gyorgy Board B310 CHEMICAL BIOLOGY APPROACHES TO UNDERSTAND MITOCHONDRIA INSULIN SECRETORY GRANULE MEMBRANE CONTACT SITES. Rachel E. Knight 1304-Pos Board B311 QUANTITATIVE ANALYSIS OF CLUSTERING AND SPATIAL VISUALIZATION OF INSULIN SECRETORY GRANULES IN PANCREATIC Β CELLS. Riva Manav Verma , Kevin S. Chang, Aneesh Deshmukh, Kate L. White 1305-Pos Board B312 UNBIASED SEPARATION AND EXPLORATION OF INSULIN SECRETORY GRANULES VIA DIELECTROPHORESIS. Ashley Archambeau , Teji Korma, Mark Hayes, Kate L. White 1306-Pos Board B313 UNSUPERVISED CLUSTERING-BASED APPROACH TO IDENTIFY INSULIN SECRETORY GRANULE SUBPOPULATIONS USING SOFT X-RAY TOMOG RAPHY. Kevin S. Chang , Aneesh Deshmukh, Valentina Loconte, Kate L. White 1307-Pos Board B314 CHEMICAL BIOLOGY APPROACHES FOR MAPPING PEPTIDE HORMONE MATURATION. Kate L. White 1308-Pos Board B315 COLONY CONTEXT AND SIZE-DEPENDENT COMPENSATION MECHA NISMS GIVE RISE TO VARIATIONS IN NUCLEAR GROWTH TRAJECTO RIES. Chantelle L. Leveille , Julie C. Dixon, Christopher L. Frick, . Allen Institute for Cell Science, Julie Theriot, Susanne M. Rafelski 1309-Pos Board B316 3D CELL MAPPING OF INSULIN SECRETORY GRANULE MATURATION. Aneesh Deshmukh , Valentina Loconte, Kate L. White 1310-Pos Board B317 A ROLE FOR THE BRIDGE-LIKE LIPID TRANSFER PROTEIN VPS13D IN THE CONTROL OF MEMBRANE DYNAMICS AT THE TRANS GOLGI/TGN. Chase Amos , Kenshiro Fujise, Berrak Ugur, Michael G. Hanna, Peng Xu, Pietro Board B318 THE OSMOTIC MECHANISM OF NUCLEAR-TO-CELL VOLUME RATIO IN YEAST. Joël P.C. Lemiere , Fred Chang 1312-Pos Board B319 A-SYNUCLEIN IMPAIRS NEURONAL MITOCHONDRIAL TRANSFER VIA MAMS IN PARKINSON’S DISEASE. Elisabeth Fritsch , Melissa Birol Voltage-Gated K Channels II (Boards B320 - B344) 1313-Pos Board B320 REGULATION OF HCN4 CHANNELS BY THE N-TERMINUS OF IRAG. Lucas M. Blecker , Avery Langley, William G. Nichols, Daniel Enders, Colin H. Peters, John Bankston, Cathy Proenza 1314-Pos Board B321 MOLECULAR MODEL OF TRIP8B-HCN1 INTERACTION AT THE CYCLIC NUCELOTIDE BINDING DOMAIN BINDING SITE. Kathleen G. Bickel , Yongchang Chang, Vinay Idikuda, Baron Chanda Hajnoczky 1303-Pos De Camilli 1311-Pos

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