BPS2025 Full Program

1443-Pos Board B450 REGULATED CONFINEMENT PATTERNS ELICIT THE ORGANIZED COL LECTIVE MIGRATION OF REAR CELLS. Mitsuru Sentoku , Miki Takei, Masaharu Endo, Tatsuya Chono, Kenji Yasuda 1444-Pos Board B451 CAPTURING CONFINEMENT IN CELL MIGRATION WALK MODELS. Maya Rowell , Badri Narayanan Narasimhan, Parag Katira, Stephanie I. Fraley 1445-Pos Board B452 FUNCTIONAL ANALYSIS OF F-ATPASE MOTION USING MULTISCALE SIMULATIONS. Shintaroh Kubo , Hiroyuki Noji 1446-Pos Board B453 SHEPHERDING PROTEIN ALONG A MICROTUBULE. Leila Farhadi , Shane A. Fiorenza, Sithara Wijeratne, Konstantinos Nakos, Meredith D. Bet terton, Radhika Subramanian 1447-Pos Board B454 PRINCIPLES OF CELLULAR BEHAVIOR: INTEGRATING CELLULAR STRUC TURE, DYNAMICS, AND DECISION MAKING IN A UNICELLULAR WALK ER. Ben T. Larson , Wallace Marshall 1448-Pos Board B455 Travel Award Winner THE MECHANICAL ENERGY COST OF DIVISION IS MAXIMIZED DURING SHAPE ELONGATION IN DIVIDING MODEL CELLS. Ryota Sakamoto , Michael P. Murrell 1449-Pos Board B456 ROBUST QUANTIFICATION OF CELLULAR AND NUCLEAR MECHAN ICS. Wessel Rodenburg, Jorine M. Eeftens 1450-Pos Board B457 HIGHER ORDER MODEL OF AMOEBOID T-CELL MIGRATION IN COMPLEX MICROENVIRONMENTS UNIFIES CELL CORTEX, MICROTUBULES AND NUCLEUS MECHANICS INTO A SINGULAR SYSTEM. Erdem Tabdanov 1451-Pos Board B458 CHEMICAL COMPENSATION TO MECHANICAL LOSS VIA PI3K/AKT-NHE1 CROSSTALK. Qin Ni , Zhuoxu Ge, Anindya Sen, Konstantinos Konstanto poulos, Sean Sun 1452-Pos Board B459 VISCOELASTIC MECHANICS! NOT ELASTIC REGULATES CANCER CELL MEMORY AND CYTOSKELETON CONTRACTION. Yan Lu 1453-Pos Board B460 OPTIMIZATION OF THERAPEUTIC T CELLS THROUGH BIOPHYSICAL MOD ELING. Roberto Alonso Matilla , Paolo P. Provenzano, David J. Odde 1454-Pos Board B461 COLLECTIVE EFFECTS OF PRESTIN IN HIGH FREQUENCY AMPLIFICA TION BY OUTER HAIR CELLS. Aditya Nandy , Gregory Rassolov, Carlos Floyd, Patrick R. Haller, Benoit Roux, Eduardo Perozo, Suriyanarayanan Vaikuntanathan 1455-Pos Board B462 MECHANICAL STRAIN CAUSES HERITABLE MUTATIONS. Dennis E. Discher , Markus T. Sprenger, Alisya Anlas 1456-Pos Board B463 ILLUMINATING MECHANOTRANSDUCTION IN BREAST CANCER METASTASIS USING OPTOGENETIC VINCULIN AND SPECTR, A SIMPLE AND SENSITIVE METHOD TO VISUALIZE VINCULIN CONFORMATIONAL CHANGES. Joseph M. Szulczewski , Mingyu Choi, Saygin Gulec, Gabe Kreider-Letterman, Klaus M. Hahn

1457-Pos Board B464 CELLULAR PROTRUSION GENERATION AND LENGTH SCALE DEPEND ON CURVATURE CUES AND ACTIN NETWORK BALANCES. J. Michael Henderson , Feng-Ching Tsai, Nina Ljubojevic, Sevan Belian, Thibault Chaze, Mariette Matondo, Yosuke Senju, Pekka Lappalainen, Patricia M. Bassereau, Chiara Zurzolo Cytoskeletal-based Intracellular Transport (Boards B465 - B467) 1458-Pos Board B465 KINESIN-1 AUTOINHIBITION TUNES CARGO TRANSPORT BY MOTOR ENSEMBLES. Brandon M. Bensel , Patricia M. Fagnant, Samantha Beck Previs, Kathleen M. Trybus, Sam Walcott, David M. Warshaw 1459-Pos Board B466 TAU HYPERPHOSPHORYLATION IMPAIRS COOPERATIVE BINDING TO MICROTUBULES AND PERTURBS ORGANELLE TRAFFICKING IN NEU RONS. Daniel Beaudet , Christopher L. Berger, Adam G. Hendricks 1460-Pos Board B467 LOCAL CYTOPLASMIC TRADEWINDS DIRECT SOLUBLE PROTEINS TO THEIR TARGETS. Catherine G. Galbraith , Brian P. English, Ulrike Boehm, James Galbraith Novel Techniques for Systems and Synthetic Biology (Boards B468 - B471) 1461-Pos Board B468 A TOOL FOR DETERMINING THE RELEASE RATE AND NUMBER OF MRNA MOLECULES RELEASED FROM LIPID NANOPARTICLES IN CELLS BASED ON FLUORESCENCE READOUT AND SIMULATION. Frank H. Schulz , Emily W. Sørensen, Steen W.B. Bender, Nikos S. Hatzakis 1462-Pos Board B469 MOLECULAR TIME CAPSULES ENABLE TRANSCRIPTOMIC RECORDING IN LIVING CELLS. Jack Rubien , Mirae Parker, Dylan McCormick, Gene-Wei Li 1463-Pos Board B470 AN INNOVATIVE APPROACH FOR CONDUCTING 3D ELECTROPHYSIOLOG ICAL RECORDINGS WITHIN INTACT ORGANOIDS. Jeffrey Netzeband 1464-Pos Board B471 COBY: AN ADVANCED TOOL FOR ACCURATE CREATION OF COARSE GRAINED SIMULATION SYSTEMS. Mikkel D. Andreasen, Paulo Cesar T. Souza, Birgit Schiøtt, Lorena Zuzic Molecular and Cellular Neuroscience (Boards B472 - B481) 1465-Pos Board B472 INTERCELLULAR COMMUNICATION DISRUPTED IN ALZHEIMER’S DIS EASE. Lila Gordon , Artur Gevorgyan, Priyanka Narayan, Justin W. Taraska 1466-Pos Board B473 NEURON-ASTROCYTE COUPLED LIPID CLEARANCE DYSFUNCTION IN PARKINSON’S DISEASE. Paula Santos Otte , Philipp Selenko, Melissa Birol 1467-Pos Board B474 NEURONAL GROWTH IS INDEPENDENT OF SUBSTRATE RIGIDITY IN 2D. Zachary Carman , Isabella Phillips, Arsha Moorthy, Abdulraheem Kaimari, Alireza Sarvestani, Chamaree de Silva 1468-Pos Board B475 FLUORESCENT DETECTION OF CA 2+ AND CAMP TO CHARACTERIZE MUSCARINIC LIGANDS USING LIVE CELL IMAGING. Cassandra M. Vance , Elizabeth S. Geisler, Jose M. Eltit

M O N D A Y

95