BPS2025 Full Program

Myosins (Boards B423 - B437)

1428-Pos Board B435 UNDERSTANDING STABILITY OF HUMAN CARDIAC MYOSIN PROXIMAL TAIL DIMER AND TAIL-HEAD INTERACTION. Aarushi Naskar , Ritwija Bhattacharjee, Yuri Nesmelov 1429-Pos Board B436 AUTOMATED TRACKING OF ACTIN LEARNED STRUCTURES (ATLAS) IN THE MOTILITY ASSAY. Sebastian Duno-Miranda , David M. Warshaw, Shane R. Nelson 1430-Pos Board B437 Travel Award Winner INTRINSICALLY DISORDERED REGIONS ARE CRUCIAL FOR MYOSIN 10 CARGO BINDING AS REVEALED BY HDX/XL-MS & DNA-PAINT. Julia Shangguan , Allen Huff, Samuel Weng, Susanne Reinhardt, Ralf Jung mann, Ronald S. Rock, Tobin R. Sosnick Cell Mechanics, Mechanosensing, and Motility II (Boards B438 - B464) 1431-Pos Board B438 OPTICAL IMAGING OF SUB-CELLULAR FLUCTUATIONS WITHIN HAIR CELLS. Martín A. Toderi , Dzmitry Vaido, Dolores Bozovic 1432-Pos Board B439 MEASURE SINGLE-MOLECULE FORCE DURATION AND LOADING RATE IN LIVING CELLS WITH DNA-BASED FORCECHRONO PROBE. Zheng Liu 1433-Pos Board B440 HIGH-THROUGHPUT MEASUREMENT OF INTERCELLULAR FORCES VIA LIPID-DNA CONJUGATES. Priyanka Bhattacharyya , Mingxu You 1434-Pos Board B441 IMAGING PHAGOCYTIC FORCE OVER SURFACE-BOUND PARTICLES BY MACROPHAGES. Subhankar Kundu 1435-Pos Board B442 A COMPUTATIONAL MODEL OF DROSOPHILA FURROW INVAGINATION DURING CELLULARIZATION. Kyle T. Stark , Mayte Bonilla Quintana, Anna Marie Sokac, Padmini Rangamani 1436-Pos Board B443 CELL-CELL COMMUNICATION PATTERNS IN GROWING TISSUES. Abdul Malmi Kakkada , Jonathan Dawson 1437-Pos Board B444 HIGH-CONTENT TRACTION-FORCE MICROSCOPY CAN CLUSTER CELLS BASED ON THEIR MECHANOTYPE. Nicolas Desjardins-Lecavalier , San tiago Costantino 1438-Pos Board B445 TRACTION FORCE MICROSCOPY REVEALS THAT THE FIBER NETWORKS ENHANCE TRACTION FORCE AND DIRECTIONALITY BUT NOT SPEED. Gopal Niraula 1439-Pos Board B446 QUANTIFY MOLECULAR FORCES IN LIVE CELLS USING TANDEM TENSION SENSOR. Xuefeng Wang 1440-Pos Board B447 CRACKING THE CODE OF NUCLEAR RIGIDITY: NEW FRONTIERS IN CELL MIGRATION AND THERAPY. Yerbol Tagay 1441-Pos Board B448 EFFECT OF FREEZING ON THE MECHANICAL PROPERTIES OF SKINNED MUSCLE CELLS. Venus Joumaa , Birtej Mangat, Christopher Roberts, Mahmoud Abu Sara, Shuyue Liu, John Holash, Walter Herzog 1442-Pos Board B449 PROBING NUCLEAR MECHANICS ACROSS CELL DIVISION THROUGH PRO TEIN DIFFUSION. Niaz Z. Goodbee , Mary W. Elting, Sharonda J. LeBlanc

1416-Pos Board B423 REGULATION OF MYOSIN-DEPENDENT STEREOCILIA TRAFFICKING BY CENTRIN-2. James B. Heidings , Zane Moreland, Elli Hartig, John Garcia, Basile Tarchini, Jonathan Bird 1417-Pos Board B424 SINGLE-MOLECULE INSIGHTS INTO USHER PROTEIN DYNAMICS AND DEAFNESS. Marvin Wright , Neil Billington, Rong Liu 1418-Pos Board B425 A SINGLE MOLECULE MECHANICAL CHARACTERIZATION OF MYO3A. Kayleigh J. Boos , Jinghua Ge, Christopher M. Yengo, Edward P. Debold 1419-Pos Board B426 ATOMISTIC SIMULATION STUDY ON MECHANICAL WORK GENERATION VIA ATP HYDROLYSIS BY MYOSIN. Ikuo Kurisaki, Madoka Suzuki 1420-Pos Board B427 MULTISCALE APPROACH AND ATOMIC RESOLUTION INSIGHTS FOR THE DYSREGULATION LEADING TO CARDIOMYOPATHIES. Anne M. Houdusse , Laurie Lannes, Daniel Auguin, Carlos M. Kikuti, Marie Juille, Neha Nand wani, James A. Spudich, Kathleen Ruppel, Julien Robert-Paganin 1421-Pos Board B428 DEVELOPMENT OF THE HOMO-FRET ASSAY TO IDENTIFY COOPERATIVE CLUSTER OF MYOSIN HEADS BOUND TO ACTIN FILAMENTS. Ritwija Bhattacharjee , Benjamin Ryan, Yuri E. Nesmelov 1422-Pos Board B429 ANTI-MYOSIN SUBFRAGMENT-2 PEPTIDES ELEVATE MYOSIN ATPASE ACTIVITY. Maryam Arabi, Md Mozammel Hossain, Douglas D. Root 1423-Pos Board B430 MAVACAMTEN AND OMECAMTIV MECARBIL MODULATE THE STRUC TURE OF THE INTERACTING-HEADS MOTIF BY INDUCING DISTINCT SUBFRAGMENT-2 CONFORMATIONS. Arun Kumar Somavarapu , Jinghua Ge, Christopher M. Yengo, Raul Padron, Roger Craig 1424-Pos Board B431 CARDIAC MYOSIN 25HEP E525K MUTATED CONSTRUCT WITH MAVA CAMTEN IS STABILIZED BY THREE BLOCKED HEAD SUBFRAGMENT2 INTERACTIONS. Ruchi Sharma , Jinghua Ge, Christopher M. Yengo, Roger Craig, Raul Padron 1425-Pos Board B432 A CRITICAL SALT BRIDGE BETWEEN THE RELAY HELIX AND ACTIVATION LOOP IN BETA-CARDIAC MYOSIN COORDINATES ACTIN ACTIVATION OF THE POWER STROKE AND PHOSPHATE RELEASE. Skylar M.L. Bodt , Wen Ma, Christopher M. Yengo 1426-Pos Board B433 THE ROLE OF LOOP 2 CONFORMATION IN ACTOMYOSIN COMPLEX FOR MATION AND CARDIOMYOPATHY CAUSED BY THE MUTATIONS E525K AND V606M. Kalen Z. Robeson , Matthew C. Childers, Jennifer M. Davis, Michael Regnier 1427-Pos Board B434 TWO DROSOPHILA MYOSIN CARDIAC ISOFORMS ASSEMBLE NORMALLY IN INDIRECT FLIGHT AND JUMP MUSCLES BUT EXHIBIT UNIQUE BIO PHYSICAL AND BIOCHEMICAL PROPERTIES. Jared Rafael T. Camillo , Kay lyn M. Bell, Clara L. Neal, Morgan I. Mullens, Andrew G. Alvarez, Kayln D. Hazen, Alexandria G. Seifert, Anna Blice-Baum, William A. Kronert, Anthony Cammarato, Douglas M. Swank, Sanford I. Bernstein

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