BPS2025 Full Program

2587-Pos Board B51 DISEASE ASSOCIATED POINT MUTATIONS PROBE THE BIOPHYSICS OF CALMODULIN CALCIUM HANDLING AND CONFORMATIONAL CHANGE. Justin R. Lovett , Sara A. Garcia, Emily M. Campbell, Christo pher N. Johnson 2588-Pos Board B52 UNEXPECTED MICHAELIS-MENTEN BEHAVIOR OF COMPLEX MARKOV MODELS. Malte Schäffner , Helmut Grubmuller 2589-Pos Board B53 DYNAMICS OF PHOTOSYSTEM II: THE ALLOSTERIC-LIKE REGULATION OF REDOX MECHANISMS BY WATER. Jinchan Liu , Ke R. Yang, Gary W. Brudvig, Victor S. Batista 2590-Pos Board B54 DEVELOPMENT AND STRUCTURAL ELUCIDATION OF A FLUORESCENT ANTIBODY SENSOR DEPENDENT ON ALLOSTERIC CHANGES. Erik P. Stahl 2591-Pos Board B55 Travel Award Winner CHARACTERIZATION OF BAT CORONAVIRUS SPIKE GLYCOPROTEIN DY NAMICS VIA MOLECULAR DYNAMICS SIMULATIONS. Toheeb A. Balogun , Cory M. Acreman, Fiona L. Kearns, Alexandra L. Tse, Gorka Lasso, Emily H. Miller, Kartik Chandran, Jason S. McLellan, Rommie E. Amaro 2592-Pos Board B56 STRUCTURAL FLUCTUATIONS OF HUMAN CALMODULIN AT LOW CAL CIUM SATURATIONS. Karoly Liliom , Gusztav Schay, Gergely Burkódi, J Michael Klopf, Laszlo Smeller, Franci Merzel, Miklós Kellermayer, Erika Balog 2593-Pos Board B57 UNDERSTANDING STRUCTURAL DYNAMICS OF ALLOSTERY ACROSS TIME- AND LENGTH SCALES. Steffen Wolf , Veronika Frank, Christian Beck, Benedikt Sohmen, Tilo Seydel, Ingo Hoffmann, Bianca Hermann, Mark F. Nueesch, Marco Grimaldo, Gerhard Stock, Frank Schreiber, Felix Roosen-Runge, Thorsten Hugel 2594-Pos Board B58 USING DYNAMICAL-NONEQUILIBRIUM MD SIMULATIONS TO UNDER STAND DRUG RESISTANCE AND ALLOSTERY IN PROTEINS. Sofia Oliveira , Adrian J. Mulholland 2595-Pos Board B59 DYNAMICS AND COMMUNICATION OF MULTIDOMAIN STEROID RECEP TORS REVEALED THROUGH ACCELERATED AND NONEQUILIBRIUM MO LECULAR DYNAMICS SIMULATIONS. Jordan A. Wenning , Denise Okafor 2596-Pos Board B60 REVEALING SITE-SPECIFIC THERMAL NETWORKS IN OMP-DECARBOXYL ASE: DRIVERS OF ENTHALPIC BARRIER CROSSING AND CATALYSIS. Pankaj Dubey , Anish Somani, Jessica Lin, Anthony T. Iavarone, Judith P. Klinman 2597-Pos Board B61 CREATING 3D MOVIES FROM 2D CRYO-EM SNAPSHOTS OF BIOLOGICAL MOLECULES: BRIDGING DEEP LEARNING-BASED CRYO-EM IMAGE ANAL YSIS WITH MOLECULAR SIMULATION FOR PROTEIN CONFORMATIONAL DYNAMICS. Anupam A. Ojha , Sonya M. Hanson, Rommie E. Amaro 2598-Pos Board B62 STRUCTURAL CONTEXT OF THE UEV DOMAIN, TSG101 AND BE YOND. David Nyenhuis , Jose Vazquez, Nico Tjandra 2599-Pos Board B63 INTEGRATIVE HDX: FROM POST HOC ENSEMBLE REWEIGHTING TO HDX MS GUIDED ENHANCED SAMPLING MD SIMULATIONS. Juliet O. Obi, Ally K. Smith, Kyle C. Kihn, Daniel J. Deredge

2600-Pos Board B64 HOW SINGLE SITE BIASES AND PAIRWISE COUPLING IN PROTEIN SE QUENCES AFFECT COOPERATIVITY AND ALLOSTERY. Soumya P. Behera , Ananya K. Majumdar, Doug Barrick Membrane Protein Structures II (Boards B65 - B83) 2601-Pos Board B65 MEMBRANOMEX FOR COMPREHENSIVE ANALYSIS OF SINGLE-PASS TRANSMEMBRANE PROTEINS AND THEIR COMPLEXES. Lakhini Ponoop P. Patro , Zigang Song, Alexey Kovalenko, Irina D. Pogozheva, Andrei L. Lomize, Wonpil Im 2602-Pos Board B66 MECHANISMS OF DYSFERLIN-MEDIATED MEMBRANE REPAIR IN HEALTH AND DISEASE. Hsiang-Ling Huang , Giovanna Grandinetti, Sarah M. Heissler, Krishna Chinthalapudi 2603-Pos Board B67 MEMPRO: MEMBRANE PROTEIN ORIENTATION IN LIPID BILAYERS. Matyas Parrag , Phillip J. Stansfeld 2604-Pos Board B68 MUTAGENESIS OF CLAUDIN-15 REVEALS STRUCTURAL BASIS FOR CHANNEL ASSEMBLY AND ION SELECTIVITY IN TIGHT JUNCTIONS. Sarah McGuinness , Samaneh Sajjadi, Fatemeh Khalili-Araghi 2605-Pos Board B69 STRUCTURAL INSIGHTS INTO EPHA2 DIMERIZATION AND MEMBRANE INTERACTIONS: ROLES OF THE TRANSMEMBRANE AND JUXTAMEM BRANE REGIONS IN SIGNALING MECHANISM. Amita R. Sahoo , Matthias Buck 2606-Pos Board B70 Travel Award Winner TOWARDS HIGH-RESOLUTION STRUCTURAL CHARACTERIZATION OF GLYCOPROTEINS EXPRESSED ON NANOSIZED PARTICLES VIA CRYOGENIC TRANSMISSION ELECTRON MICROSCOPY (CRYO-TEM). Jiaan Li 2607-Pos Board B71 BIOPHYSICAL APPROACHES TO STUDY VIRAL PROTEINS AT THE CEL LULAR MEMBRANES. Elka R. Georgieva , Md Majharul Islam, Adeyemi Ogunbowale, Saman Majeed, Lan Dang, Peter P. Borbat, Olamide Ishola, Elaheh Hadadianpour, Arvin S. Delkhosh, Juan C. Rueda Amador, Steven Ludtke 2608-Pos Board B72 STRUCTURE OF THE HUMAN DOPAMINE TRANSPORTER AND MECHA NISMS OF ALLOSTERIC INHIBITION. Dushyant Kumar Srivastava , Vikas Navratna, Dilip K. Tosh, Audrey Chinn, Md Fulbabu Sk, Emad Tajkhor shid, Kenneth A. Jacobson, Eric Gouaux 2609-Pos Board B73 A NOVEL DETERGENT-FREE VESICLE-BASED STRUCTURE DETERMINA TION SYSTEM OF MEMBRANE PROTEINS. Hang Liu 2610-Pos Board B74 EPR SPECTROSCOPIC CHARACTERIZATION OF THE TOPOLOGY OF SARS COV-2 ENVELOPE PROTEIN. Andrew K. Morris 2611-Pos Board B75 NATIVE DGC STRUCTURE RATIONALIZES MUSCULAR DYSTROPHY-CAUS ING MUTATIONS. Shiheng Liu , Tiantian Su, Xian Xia, Z. Hong Zhou 2612-Pos Board B76 STRUCTURAL ELEMENTS AFFECTING RETINAL STABILITY IN CONE OP SINS. Weekie Yao , David L. Farrens

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