BPS2025 Full Program

2613-Pos Board B77 STRUCTURAL AND FUNCTIONAL INVESTIGATION OF RYANODINE RECEP TOR 1 WITH ENDOGENOUS LIGANDS AND DRUGS. Kookjoo Kim , Huan Li, Qi Yuan, Zephan Melville, Ran Zalk, Amedee des Georges, Joachim Frank, Wayne A. Hendrickson, Andrew R. Marks, Oliver B. Clarke 2614-Pos Board B78 LIPIDOMIC AND STRUCTURAL INVESTIGATION OF NANODISC RECON STITUTED MEMBRANE PROTEINS. Lottie R. Steward , Myeongseon Lee, Ryan E. Hibbs, Michael H.B. Stowell 2615-Pos Board B79 Travel Award Winner DECODING THE MECHANISM OF IRON PIRACY IN PATHOGENIC NEIS SERIA. Shubham Dubey , Gabriel Bury, Peihang Li, Yulia Pushkar, Nicholas Noinaj 2616-Pos Board B80 NOVEL MUTATIONS OF CLAUDIN-2 ION CHANNELS REVEAL ITS THREE DIMENSIONAL ASSEMBLY. Samaneh Sajjadi , Maryam Mohebbi, Fate meh Khalili-Araghi 2617-Pos Board B81 INVESTIGATIONS INTO THE STRUCTURAL BASIS FOR RECEPTOR ACTIVA TION BY CYSTINE-KNOT HORMONES. Guanqi Lu 2618-Pos Board B82 Travel Award Winner STRUCTURE DETERMINATION OF MEMBRANE PROTEINS USING DNA BASED NANODISCS. Soumya Chandrasekhar , Christopher M. Maffeo, Aleksei Aksimentiev, Thorsten Schmidt 2619-Pos Board B83 STRUCTURAL INSIGHTS INTO TAS2R46: ROLE OF EXTRACELLULAR LOOP 2 CONFORMATIONS AND STABILITY IN BITTER TASTE RECEPTOR FUNC TION. Soo-Kyung Kim , Ruth Pachter, William A. Goddard Membrane Protein Folding (Boards B84 - B91) 2620-Pos Board B84 STABLE AND MINIMUM-SIZE SOLUBILIZATION OF GPCRS WITH COCK TAILS OF PHOSPHOLIPID ANALOGS. Katsumi Matsuzaki , Mai Takagi, Ayana Nagatani, Kenichi Kawano, Ayami Hata, Azusa Yokoyama, Koichi Hayashida, Haruka Hoshi, Yusuke Kuroda, Yousuke Yamaoka, Takahiro Fujiwara, Yohei Miyanoiri, Masaru Hoshino, Yoshiaki Yano, Kiyosei Takasu 2621-Pos Board B85 EVALUATION OF PROPERTIES OF NOVEL PHOSPHOLIPID ANALOGS BASED ON LIGAND BINDING ABILITY OF A SOLUBILIZED GPCR. Haruka Hoshi , Kenichi Kawano, Takahiro Fujiwara, Yusuke Kuroda, Yousuke Yamaoka, Kiyosei Takasu, Katsumi Matsuzaki 2622-Pos Board B86 DECIPHERING P HLIP’S DYNAMIC FOLDING AND MEMBRANE INTERAC TIONS VIA 2D IR SPECTROSCOPY. Raiza Nara Antonelli Maia , Carlos R. Baiz 2623-Pos Board B87 MEMBRANE AND ALCOHOL MODULATION OF SNAP-25 STRUCTURES DETERMINED VIA CIRCULAR DICHROISM. Tanner M. Blocker , Thomas D. Weed, Jonah R. Beck, Jason T. Carlson, Christopher E. Hunt Jr., Joseph H. Jackson, Dixon J. Woodbury 2624-Pos Board B88 A THERMODYNAMIC INTERMEDIATE OF OUTER MEMBRANE PROTEIN OMPLA IS PARTLY EXPOSED. Lucas Shen , Karen G. Fleming

2625-Pos Board B89 THE VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL HVDAC1 FORMS A Β-BARREL-LIKE STRUCTURE IN AN AQUEOUS FOLDING INTER MEDIATE EVEN IN THE ABSENCE OF LIPID BILAYERS OR MICELLES. Sara Gholami, Joerg H. Kleinschmidt 2626-Pos Board B90 STERIC PACKING MODES STABILIZING MEMBRANE PROTEIN FOLDING AND ASSEMBLY REVEALED BY AFM-BASED FORCE SPECTROSCOPY. Huiy ing Yang, Zhangyi Zhou, Daihong Zhou, Mojie Duan, Hao Yu 2627-Pos Board B91 INSIGHTS INTO THE DYNAMICS OF RNC-SECYEG COMPLEX BY FCS. Justas Kvietkauskas , Damir Sakhapov, Xiaolin Wang, Joerg Enderlein, Marina Rodnina Enzyme Function, Cofactors, and Post-Translational Modifications (Boards B92 - B112) 2628-Pos Board B92 TOXIC SPLIT: AETD’S DEADLY DIVERGENCE FROM SKTA. August J. Krueger , Maria-Eirini Pandelia, Douglas Theobald 2629-Pos Board B93 CHARACTERIZATION OF CARBONIC ANHYDRASE-LIKE ENZYMES IN PLANT ALKALOID BIOSYNTHESIS. Jaime E. Martinez Grundman , Eric A. Fields, Ryan S. Nett 2630-Pos Board B94 CATALYTIC MECHANISM OF A BIFUNCTIONAL RIBONUCLEASE WITH A SINGLE METAL-ION. Ankur K. Singh , Kalaiarasi Chinnasamy, Balasubra manian Gopal 2631-Pos Board B95 MUTATIONAL ANALYSES OF THE SUBSTRATE BINDING SITE OF A COCOONASE. Nana Sakata , Yuri Murakami, Orika Ashida, Mitsuhiro Miyazawa, Shigeru Shimamoto, Yuji Hidaka 2632-Pos Board B96 COMPUTATIONAL ANALYSIS OF SOLVENT TO ACTIVE SITE THERMAL EN ERGY TRANSFER NETWORKS IN LIPOXYGENASE. Yaoyukun Jiang , Jaden P. Cordova, Judith P. Klinman 2633-Pos Board B97 CAVITRACER : A PRODY TOOL FOR MAPPING PROTEIN TUNNELS AND CHANNELS WITH APPLICATION IN LIPOXYGENASES. Eryk Trzcinski, James M. Krieger, Julia Duda, Karolina Mikulska-Ruminska 2634-Pos Board B98 DIFFERENTIAL KINETICS OF AMINOPEPTIDASE CLEAVAGE OF AMINO ACID SPECIES FROM HETERO-OLIGOMERIC PEPTIDES DETECTED BY A BIOLOGICAL NANOPORE. Atefeh Akbari, Catherine Xiao , Jessica Schwaiger, Priyanka Jain, Tobias Ensslen, Jan C. Behrends 2635-Pos Board B99 NANOPORE APPROACH FOR TEMPORAL OMICS AT SINGLE-MOLECULE LEVEL: CROSSTALK IN THE RENIN-ANGIOTENSIN SYSTEM. Jun-ge li , Jie Jiang, Hongyan Niu, Yan Gao, Meng-Yin Li, Yi-Tao Long 2636-Pos Board B100 UNRAVELING THE CATALYTIC MECHANISM OF THE SARS-COV-2 MACRO DOMAIN ADP-RIBOSYLHYDROLASE. Rishav Mitra , Galen Correy, James Fraser 2637-Pos Board B101 IDENTIFYING HYDROLASE ACTIVITY IN PROTEINS OF UNKNOWN FUNC TION. Julia R. Koeppe , Slater Bushen, Cheyenne Titus, Jake Kilrain, Yakira Jack, Grace Stryker

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