BPS2025 Full Program

2664-Pos Board B128 INVESTIGATING THE EFFECTS SPECIFIC PHOSPHORYLATION HAS ON THE BINDING OF ALPHA-SYNUCLEIN TO LIPOSOMES. Nicholas Scurato , Peter J. Chung 2665-Pos Board B129 STRUCTURAL INVESTIGATIONS OF IDRS IN Α-SYNUCLEIN FIBRILS VIA SITE-SELECTIVE 2 H-NMR. Emily-Elizabeth Cardenas 2666-Pos Board B130 INTERACTIONS OF MEMBRANE WITH AMYLOID BETA AND PREVENTA TIVE APPROACHES IN ALZHEIMER’S DISEASE. Zoya Leonenko , Carina T. Filice, Nanqin Mei, Yue Xu, Danielle M. McRae 2667-Pos Board B131 PROLINE ISOMERIZATION AND ITS EFFECT ON SH3-ARKA BINDING. Liz beth Mendoza , Raymond B. East, Elliott J. Stollar, K. Aurelia Ball 2668-Pos Board B132 BUFFER-INDUCED CHANGES IN THE CONFORMATIONS OF INTRINSICAL LY DISORDERED PROTEINS UNCOVERED BY NATIVE MASS SPECTROME TRY USING SUBMICRON ELECTROSPRAY IONISATION EMITTERS. Emily J. Byrd , Emma Norgate, Chalmers Chau, Paolo Actis, Antonio N. Calabrese 2669-Pos Board B133 Travel Award Winner PHASE TRANSITION OF GVPU REGULATES GAS VESICLE CLUSTERING IN BACTERIA. Zongru Li 2670-Pos Board B134 NANOPLASTIC PROMOTES THE AMYLOID AGGREGATION OF AMYLOID BETA AND ALPHA-SYNUCLEIN. Gangtong Huang , Pu Chun Ke, Feng Ding 2671-Pos Board B135 UNTANGLING THE ROLE OF DISTINCT LIPID COMPOSITIONS IN THE INI TIAL MEMBRANE-BINDING OF TAU PROTEIN AT THE SINGLE-MOLECULE LEVEL. Joana Paixão, Ana Coutinho, Ana Azevedo, Manuel Prieto, Martin Hof, Ana M. Melo 2672-Pos Board B136 OLIGOMERIZATION-DEPENDENT PROTEIN AND DNA COMPACTION OF DISORDERED DNA BINDING DOMAIN OF TUMOR SUPPRESSOR PALB2 SUGGESTS NOVEL STRAND EXCHANGE MECHANISM. Yevhenii Kyriukha, Maxwell Watkins, Jennifer Redington, Nithya Chintalapati, Abhi Ganti, Jesse B. Hopkins, Reza Dastvan, Nicola Pozzi, Vladimir N. Uversky, Sergey Korolev 2673-Pos Board B137 PHYSIOLOGICAL AND PATHOLOGICAL ROLE OF TAU’S PROLINE RICH RE GION IN MICROTUBULE ASSEMBLY. Christopher R. Brue , Karen Acosta, Leland C. Mayne, Elizabeth Rhoades 2674-Pos Board B138 SINGLE-MOLECULE CONFORMATIONAL COMPLEXITY IN DISORDERED REGIONS OF FUSION ONCOPROTEINS. Debapriya Das , Daniel Scholl, Aaron H. Phillips, Richard Kriwacki, Ashok Deniz 2675-Pos Board B139 EFFECT OF DANGLING ENDS ON POLYMER DYNAMICS AND PHOTO-IN DUCED ELECTRON TRANSFER EXPERIMENTS OF IDPS. Crystal F. Ottoway, Gabor Nagy, Michael Philips, Gerdenis Kodis, Kingshuk Ghosh, Helmut Grubmuller, Sara M. Vaiana 2676-Pos Board B140 X-RAY FOOTPRINTING / MASS SPECTROMETRY OFFERS A NEW, DE TAILED VIEW OF INTRINSICALLY DISORDERED PROTEIN STRUCTURAL ENSEMBLES. Darren N. Kahan , Sayan Gupta, Max V. Staller, Corie Y. Ralston, Susan Marqusee

2677-Pos Board B141 QUANTIFYING THE CONFORMATIONAL LANDSCAPE OF THE MARGIN ALLY DISORDERED PROTEIN HYPK WITH ATOMIC SIMULATION. Kari Gaalswyk , Kingshuk Ghosh, Martin Gruebele 2678-Pos Board B142 UNCOVERING THE FUNCTION OF PROPAGATING TAU IN THE HOMEO STASIS OF NEURONAL LIPID PEROXIDATION. Anna Oliveras , Melissa Birol Condensates in Physiology and Disease (Boards B143 - B165) 2679-Pos Board B143 SEQUENCE-ENCODED MOLECULAR GRAMMAR GOVERNS THE FORMA TION OF SYNAPTIC CONDENSATES. Christian Hoffmann, Kiersten Ruff, Irina A. Edu, Min Kyung Shinn, Johannes V. Tromm, Avnika Pant, Hannes Ausserwöger, Jennifer Morgan, Tuomas P. Knowles, Rohit V. Pappu, Dragomir Milovanovic 2680-Pos Board B144 SINGLE-MOLECULE MICROSCOPY TO UNCOVER CLASS-SPECIFIC CHAP ERONE BEHAVIOR IN PROTEIN CONDENSATE DISPERSAL. Kyle M. Lin , Diangen Lin, Estefania Cuevas-Zepeda, Haneul Yoo, David A. Drummond, Allison H. Squires 2681-Pos Board B145 A ROLE OF PHASE-SEPARATED OPTINEURIN CONDENSATES IN SELEC TIVE AUTOPHAGY. Maria Georgina Herrera , Lena Kühn, Laura Krause, Verian Bader, Lisa Jungbluth, Carsten Sachse, Elias Adriaenssens, Sascha Martens, Jörg Tatzelt, Konstanze F. Winklhofer 2682-Pos Board B146 DEFINING THE BIOPHYSICAL BLUEPRINT OF INTRACELLULAR LIQUID/ SOLID PHASE COEXISTENCE. Hailey M. Tanner 2683-Pos Board B147 CHARACTERIZING STRESS GRANULE FORMATION OVER TIME IN IPSC CMS. Isabelle S. Field 2684-Pos Board B148 CHAPERONING FUNCTIONS OF BETA-IMPORTIN TNPO1 ARE REALIZED BY ITS ABILITY TO MODULATE THE PHASE BEHAVIORS OF CARGO PRO TEINS. Miriam Linsenmeier , Min Kyung Shinn, Thomas Mumford, Lukasz Bugaj, Rohit V. Pappu, James Shorter 2685-Pos Board B149 FUNCTION AND COMPOSITION OF RNA GRANULES DURING CHIKUNGU NYA VIRUS INFECTION. Diyun Sun , Jared Bard 2686-Pos Board B150 ATP CONVERTS PROTEIN-NUCLEIC ACID AGGREGATES INTO LIQUID CONDENSATES. Divya Kota 2687-Pos Board B151 NONCATALYTIC REGULATORY DOMAINS OF BRUTON’S TYROSINE KINASE MEDIATE SINGLE-COMPONENT PHASE SEPARATION. Alexander D. Fenton , Jean K. Chung 2688-Pos Board B152 HETEROTYPIC COACERVATION REGULATES COAGGREGATION OF DIETARY PROTEINS. Mily Bhattacharya , Jaspreet Kaur, Deepika Singla, Board B153 MULTIPHASE BEHAVIOR OF NUCLEOLAR COMPONENTS GOVERNS THE SPATIAL HETEROGENEITY OF THE OUTER REGION OF THE NUCLEO LUS. Priyanka Dogra , Mylene C. Ferrolino, Suparna Khatun, Michele Tolbert, Qi Miao, Shondra Miller, Aaron Pitre, George Campbell, Toler Freyaldenhoven, Eric B. Gibbs, Richard W. Kriwacki Anjali Giri 2689-Pos

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