BPS2025 Full Program

2843-Pos Board B307 TARGETING INFLAMMATION AND OXIDATIVE STRESS TO ALLEVIATE CARDIAC ARRHYTHMIA RISK IN SICKLE CELL DISEASE. Peter Bronk , Tae Yun Kim, YiChun Lu, Yangfan Jia, Samisubbu Naidu, Avinash Maun, Sage Michel, Ankit A. Desai, Peng Zhang, Bum-Rak Choi 2844-Pos Board B308 INVESTIGATING SEX DEPENDENT MECHANISMS OF ARRHYTHMOGENSIS THROUGH REDUCED-ORDER MODELING OF CA 2+ DIFFUSION. Yixuan Wu , Xianwei Zhang, William E. Louch, Michael A. Colman, Haibo Ni, Eleonora Grandi 2845-Pos Board B309 TARGETING THE PROTEIN KINASE G PATHWAY MODULATES KCNQ1 CHANNELS REVEALING POTENTIALLY IMPORTANT CONTRIBUTIONS TO CARDIAC FUNCTION AND RHYTHMICITY. Erkan Tuncay, William A. Coetzee, Belma Turan 2846-Pos Board B310 CELL STOCHASTIC RESONANCE AND MEMORY: NEW MECHANISMS UNDERLYING COMPLEX PACEMAKER FUNCTION. Akihiro Okamura , Michael P. Wang, Isabella K. He, Michael D. Stern, Edward G. Lakatta, Victor A. Maltsev 2847-Pos Board B311 EXPLORING THE MECHANISMS OF SEX-SPECIFIC PROARRHYTHMIA IN LONG QT SYNDROME THROUGH COMPUTATIONAL MODELING. Isabella Doherty , Roshni Shetty, Haibo Ni, Stefano Morotti, Eleonora Grandi 2848-Pos Board B312 INTERCALATED DISK ION CHANNEL AND GAP JUNCTION DISTRIBUTION REGULATE TISSUE CONDUCTION AND NANODOMAIN CALCIUM CUR RENTS. Nicolae Moise, Heather Struckman, Rengasayee Veeraraghavan, Seth H. Weinberg 2849-Pos Board B313 EFFECT OF CARBON MONOXIDE ON I NA RECORDED IN ICELL 2 HUMAN INDUCED PLURIPOTENT STEM CELL DERIVED CARDIOMYOCYTES. Moza M. Al-Owais , Arun V. Holden, Derek S. Steele 2850-Pos Board B314 COMPLEX EFFECTS OF NEUROPEPTIDE Y ON CA 2+ CHANNEL ACTIVITY IN CARDIAC VENTRICULAR MYOCYTES. Chase M. Fiore , Shailesh R. Agar wal, Kalyanam Shivkumar, Robert D. Harvey 2851-Pos Board B315 A CROSS-BRIDGE CYCLING MODEL FOR UNDERSTANDING THE ROLE OF METABOLITE ACCUMULATION IN SKELETAL MUSCLE FATIGUE. John I. Hendry , Muhammet E. Erol, Gwenael Layec, Edward P. Debold, Shiven dra G. Tewari, Anders Wallqvist, Venkat R. Pannala 2852-Pos Board B316 MATURATION OF HUMAN INDUCED PLURIPOTENT STEM CELL-DERIVED CARDIOMYOCYTES WITH TDIS ENABLES SCALABLE MEASURE OF PHYSI OLOGICAL ACTION POTENTIAL DURATIONS. Joseph J. Munier 2853-Pos Board B317 RAPID, INDUCIBLE BRUGADA SYNDROME MOUSE MODEL DISPLAYS HUMAN-LIKE SEX DIFFERENCES. Joseph J. Munier 2854-Pos Board B318 EPAC PROTEINS DOWNREGULATE K + CURRENTS IN HUMAN ATRIAL CARDIOMYOCYTES. Arthur Boileve, Margaux Aize, Laura Brard, Maximin Détrait, Adrien Leboyer, Pierre-Antoine Dupont, Alexandre Lebrun, Vladimir Saplacan, Christophe Simard, Frank Lezoualc’h, Laurent Sallé, Fabien Brette

2855-Pos Board B319 S-NITROSYLATION OF CX43 IS REQUIRED FOR Β-ADRENERGIC EN HANCED CARDIAC CONDUCTION AND CONTRACTILITY. Jonathan J. Quan , Manuel F. Munoz Camus, Thao T. Nguyen, Jorge E. Contreras 2856-Pos Board B320 UNEXPECTED NANOSTRUCTURAL REMODELING IN HEARTS OF MICE WITH A LOSS-OF-FUNCTION DEFECT IN THE NAV1.5 SODIUM CHAN NEL. Bianca Ioana Moise , Zoja Selimi, Mikhail Tarasov, Przemysław Radwański, Rengasayee Veeraraghavan 2857-Pos Board B321 Travel Award Winner INVESTIGATING THE MECHANISM OF CARDIAC CELL EXCITABILITY MOD ULATION BY A MEMBRANE-TARGETED PHOTOSWITCH. Chiara Florindi , Ludovica Cestariolo, Vito Vurro, Paola Moretti, Chiara Bertarelli, Antonio Zaza, Guglielmo Lanzani, Jose Felix Rodriguez Matas, Francesco Lodola 2858-Pos Board B322 RYR2-V2475F MUTATION IN RABBIT ALTERS ON CARDIOMYOCYTE ELEC TROPHYSIOLOGY. Garance E. Gérard , Jingjing Zheng, Hector H. Valdivia, Francisco Alvarado, Ana M. Gomez, Jean-Pierre Benitah, Romain Perrier 2859-Pos Board B323 A COMPUTATIONAL MODEL OF ANGIOTENSIN II RECEPTOR TYPE 1 DY NAMICS: INSIGHTS INTO VASCULAR REGULATION. Gonzalo Hernandez Hernandez , Mindy Tieu, Pei-Chi Yang, L. F. Santana, Colleen E. Clancy 2860-Pos Board B324 DEVELOPING A MODEL TO STUDY IPSC-CM INTEGRATION WITH HUMAN HEART TISSUE. Danika Hayman , Evangelia Psarrou, Andreia Bernardo, Cesare M. Terracciano Voltage-Gated K Channels III (Boards B325 - B346) 2861-Pos Board B325 Travel Award Winner MOLECULAR DOMAINS OF KCNE4 INVOLVED IN KV1.3 REGULA TION. Magalí Colomer-Molera , Daniel Sastre, Angela de Benito-Bueno, Paula G. Socuéllamos, Carmen Valenzuela, Antonio Felipe 2862-Pos Board B326 INVESTIGATING THE MODULATION OF KV1.3 CHANNEL INACTIVATION BY KCNE4. Purushotham Selvakumar , Magalí Colomer-Molera, Ana I. Fernández-Mariño, Antonio Felipe, Kenton Swartz 2863-Pos Board B327 STRUCTURAL AND FUNCTIONAL STUDIES PROVIDE INSIGHT INTO A NET WORK OF HYDROPHOBHIC RESIDUES THAT CONTROL INACTIVATION IN KV1.3 CHANNELS. Ana I. Fernández-Mariño , Purushotham Selvakumar, Kenton Swartz 2864-Pos Board B328 PHYSICAL MECHANISM OF FAST N-TYPE INACTIVATION IN KV CHAN NELS. Xiaofeng Tan , Ana I. Fernández-Mariño, Kenton Swartz 2865-Pos Board B329 INVESTIGATING THE COOPERATIVE ASPECT OF C-TYPE INACTIVATION OF POTASSIUM VOLTAGE-GATED CHANNELS. Zerghona Shafia , Rikard Blunck 2866-Pos Board B330 EXPLORING THE INTERACTION BETWEEN KV2.1 AND AUXILIARY AMIGO SUBUNITS USING COMPUTATIONAL AND EXPERIMENTAL APPROACH ES. Adrian Koretsky , Ana I. Fernández-Mariño, Vanessa Leone, Xiaofeng Tan, Lucy R. Forrest, Kenton Swartz

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