BPS2025 Full Program

Publications Committee Meeting 4:00 pm - 6:00 pm, Room 407 Symposium Regulatory Mechanisms in Ion Channel Gating 4:00 pm - 6:00 pm, Petree Hall C Chair Merritt Maduke, Stanford University, USA 152-Symp 4:00 pm MORE EXCITED BY OTHER PROTEINS THAN VOLTAGE: THE UNCOVEN TIONAL FUNCTION OF THE SODIUM LEAK CHANNEL COMPLEX. Stephan A. Pless No Abstract 4:25 pm SENSORY RECEPTOR DYSFUNCTION IN A NEUROGENETIC DISORDER. Julio Cordero-Morales No Abstract 4:50 pm VOLTAGE-GATED SODIUM CHANNELS AS MULTI-PROTEIN SIGNALLING COMPLEXES: THE EFFECT OF THE DISPANINS ON NAV1.7 GATING. Irina Vetter 153-SympSelect 5:15 pm PHOSPHATIDIC ACID IS AN ENDOGENOUS INHIBITOR OF PIEZO2 CHAN NELS AND MECHANOSENSITIVITY. Matthew Gabrielle, Yevgen Yudin, Xiaoyang Su, Yujue Wang, Tibor Rohacs No Abstract 5:35 pm BALL AND CHAIN GATING IN A CHLORIDE CHANNEL. Merritt Maduke Symposium Chair Klaus Hahn, University of North Carolina at Chapel Hill, USA 154-Symp 4:00 pm INTEGRINS: ENVIRONMENT RECOGNITION MACHINES ACTIVATED BY LIGAND BINDING AND ACTIN PULLING. Timothy A. Springer No Abstract 4:25 pm FORCING TUMOR INITIATION AND PROGRESSION. Valerie Weaver No Abstract 4:50 pm STRUCTURAL ORIGINS AND MECHANISMS OF THE INTEGRIN ΑI DO MAIN. Jeremy Hollis 155-SympSelect 5:15 pm DECODING COLLAGEN’S THERMALLY INDUCED UNFOLDING AND REFOLDING PATHWAYS USING AFM IMAGING. Alaa Al-Shaer, Nancy R. Forde 156-Symp 5:35 pm DOMAIN UNFOLDING AND MECHANO-TRANSDUCTION OF SINGLE TALIN AND VINCULIN MOLECULES IN LIVING CELLS. Klaus M. Hahn Platform Membrane Dynamics 4:00 pm - 6:00 pm, Room 515A Co-Chairs Teshani Kumarage, University of Illinois Urbana-Champaign, USA Sreeja Sasidharan, Lehigh University, USA Integrins and Matrix Proteins 4:00 pm - 6:00 pm, Petree Hall D

157-Plat 4:00 pm INVESTIGATING THE PERMEABILITY OF SMALL MOLECULE DRUGS AND PEPTIDES THROUGH THE BLOOD BRAIN BARRIER. Favour Ajao , Martin B. Ulmscheider, Jakob Ulmscheider 158-Plat 4:15 pm FLOW-INDUCED TRANSPORT OF LIPID-ANCHORED PROTEINS ON COS-7 CELLS. Sreeja Sasidharan , Leah Knepper, Samuel Pash, Damien Thévenin, Aurelia R. Honerkamp-Smith 159-Plat 4:30 pm EFFECT OF COAT GEOMETRY ON THE MECHANICS OF BUDDING DURING CLATHRIN-MEDIATED ENDOCYTOSIS. Xiaoyi Wu , Christopher T. Lee, Padmini Rangamani 160-Plat 4:45 pm ADVANCES IN LNP MEDIATED RNA DELIVERY: TESTING FUSOGENICITY IN ACTIVE MEMBRANES. Teshani Kumarage , Lining Zheng, Cecilia Leal 161-Plat 5:00 pm CONSTITUTIVE MACROPINOCYTOSIS IS THE MAJOR ENTRY PATHWAY OF SARS-COV-2. Sue Han , Xin Wang, Tiansheng Li, Ammar Mohseni, Ivan Kosik, Chung Yu Chan, Alberto Domingo López-Muñoz, Jessica Matthias, Reid Suddaby, Christian A. Wurm, Jonathan W. Yewdell, Ling-Gang Wu 162-Plat 5:15 pm ANTIBODY-INDUCED CHANGES IN HOST CELL MEMBRANE DYNAMICS DURING ASSEMBLY TRIGGER TUNING OF INFLUENZA A VIRION SHAPE. Anna Jaeggi-Wong , Ed Partlow, Tijana Ivanovic 163-Plat 5:30 pm INTERPLAY BETWEEN MEMBRANE SCRAMBLING AND CORTEX DETACH MENT IN CALCIUM-DRIVEN BLEB FORMATION. Adrian M. Wong , Rachel Rosal, Kevin Tharp, Padmini Rangamani, Itay Budin 164-FlashTalk 5:45 pm EXPLORING CONFINEMENT EFFECTS ON LIPID DIFFUSION ACROSS LENGTH SCALES WITH A SCALABLE PLATFORM. Nicole Voce , Paul Stevenson 165-FlashTalk 5:50 pm MARTINI3 AS A TRANSFERABLE FORCE FIELD FOR LIPOPOLYSACCHA RIDE PARAMETERIZATION. Gvantsa Gutishvili , Diane L. Lynch, James C. Gumbart 166-FlashTalk 5:55 pm INFLUENCE OF CHOLESTEROL ON THE PERMEATION OF SMALL HYDRO PHOBIC GASES THROUGH LIPID MEMBRANES: INSIGHTS FROM MO LECULAR DYNAMICS SIMULATIONS. Ridwan Sulaimon , Gilles Peslherbe Platform Protein-Nucleic Acid Interactions I 4:00 pm - 6:00 pm, Room 515B Co-Chairs Arianna Lacen, University of Alabama at Birmingham, USA Victoria Xu, Imperial College London, United Kingdom 167-Plat 4:00 pm STRUCTURAL STUDY OF ADENO-ASSOCIATED-VIRUS REPLICATION PROTEIN 40 AND ITS ROLE IN DNA ENCAPSIDATION. Victoria Xu , Joseph Barritt, Matthew Wake, Doryen Bubeck, Sarah L. Rouse 168-Plat 4:15 pm Travel Award Winner DNA COMPACTION BY CHROMOKINESIN KIF4A. Anju Yadav , Grace Cunningham, Dylan Collette, Leila Farhadi, Nandini Mani, David Dunlap, Laura Finzi, Radhika Subramanian

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