BPS2026 Program Book

1088-Pos Board B262 THE MAGNETIC SIGNATURE OF CARDIAC ALTERNANS: A COMPUTA TIONAL STUDY. Martina Nicoletti , Anna Crispino, Alessandro Loppini, Christian Cherubini, Letizia Chiodo, Alessio Gizzi, Simonetta Filippi 1089-Pos Board B263 DESIGNER PEPTIDE MODULATORS OF SODIUM CHANNELS ATTENUATE CAMKII-DEPENDENT ARRHYTHMIAS. Bence Hegyi , Paweorn Angsutara rux, Victor Alencar Almeida, Shannon Gilhooly, Nourdine Chakouri, Ryan W. Mahling, Manu Ben-Johny, Donald M. Bers 1090-Pos Board B264 SEX- AND REGION-DEPENDENT ELECTROPHYSIOLOGY AND ARRHYTH MIA VULNERABILITY IN RABBIT ATRIA. Charlotte E.R. Smith , Lianguo Wang, Amanda M. Guevara, Lilian R. Mott, Haibo Ni, Eleonora Grandi, Crystal M. Ripplinger 1091-Pos Board B265 DEVELOPMENT AND VALIDATION OF AN ISOGENIC IPSC-CM MODEL TO RECAPITULATE SEX-DIFFERENCES IN CARDIAC ELECTROPHYSIOLOGY. Erica Marquez , Jonathan R. Silva 1092-Pos Board B266 EFFECT OF THE E525K MYOSIN MUTATION ON THE MYOFILAMENT: UN DERSTANDING HYPOCONTRACTION AND HYPERCONTRACTION IN STEM CELLS FROM DIFFERENT BACKGROUNDS. Kalen Z. Robeson , Tim McMil len, Kristina B. Kooiker, Kieran Z. Fruebis, Rachelle Soriano, Andrew P. Wescott, Jennifer Davis, Michael Regnier Ion Channel Regulatory Mechanisms (Boards B267 - B294) 1093-Pos Board B267 INSECTICIDE CONTROL OF FUNCTION AND ASSEMBLY OF THE HETERO MERIC INSECT TRP CHANNEL NANCHUNG-INACTIVE. Justin G. Fedor , Ramani Kandasamy, Cheon-Gyu Park, Yang Suo, Martin Weisel, Nancy Rankl, Alexandre Nesterov, Seok-Yong Lee 1094-Pos Board B268 PLASMALOGEN-DEPENDENT MODULATION OF ORDERED MEMBRANE DOMAINS CONTROLS NEURONAL EXCITABILITY. Lucas J. Handlin , Sohelia Sabouri, Matthew Luetzen, Aubin Moutal, David Ford, Gucan Dai 1095-Pos Board B269 STRUCTURAL BASIS OF THE TOK1 POTASSIUM CHANNEL FROM CAN DIDA ALBICANS . Brice Durocher , Rían Manville, Rui Yan, Zhiheng Yu, Geoffrey Abbott, Alexandria N. Miller 1096-Pos Board B270 REVISITING THE MECHANISM OF Β-BARREL CHANNEL GATING: SALT CONCENTRATION EFFECTS, SELECTIVITY INVERSION, AND AN ELECTRO CHEMICAL GATING HYPOTHESIS. Laidy Maidel Alvero González, Deborah Aurora Perini, M. Lidón López, Antonio Alcaraz, Maria Queralt-Martin 1097-Pos Board B271 AMYLOID BETA SUPPRESSION OF KV1.2 CHANNELS INVOLVES PYK2 DEPENDENT MODULATION OF Y132. Joseph Farley , Dina Jamshidi, Jack Hyatt, Aiza Khan, Tristan Yaklin, Kristi DeBoeuf 1098-Pos Board B272 ACUTE HYPOXIA INHIBITS K 2P 3/9 WITHOUT REDUCING CYTOSOLIC [ATP] IN CAROTID BODY GLOMUS CELLS. Donghee Kim , Jiaju Wang, Dawon Kang 1099-Pos Board B273 CALCIUM STABILIZES THE OPEN STATE OF THE CRAC CHANNEL PORE. Suzanna M. Bennett , Murali Prakriya, Richard S. Lewis

1100-Pos Board B274 PATHOGENIC CALMODULIN MUTATIONS HAVE DISTINCTIVE EFFECTS ON THE CARDIAC SK CHANNELS. Yang Zheng , Ryan L. Woltz, Woori Choi, Phung Thai, Bjorn C. Knollmann, Nipavan Chiamvimonvat 1101-Pos Board B275 Travel Award Winner STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF TPC2 MODU LATION AND A NOVEL GAIN-OF-FUNCTION MUTATION IN TPC1. Rebecca Ulrike Susanna Marie Deutsch , Danusa Menegaz, Benedikt Mayer, Christine Ziegler, Dawid Jaslan, Veronika Kudrina, Katharina Dürr, Gamma Chi, Serkan Belkaya, Christian M. Grimm 1102-Pos Board B276 CHARACTERIZATION OF THE HUMAN VOLTAGE SENSING PHOSPHATASE SPECIFICITY AND REGULATION OF THE AKT/MTOR PATHWAY. Brandi Sweet 1103-Pos Board B277 PM DRIVES CA²⁺ DEPENDENT MITOCHONDRIAL STRESS AND CELL DEATH. Junhyeong Seo , Jinhong Wie 1104-Pos Board B278 STRUCTURAL BASIS OF OPPOSITE REGULATION OF HETEROMERIC GIRK1/2 AND HOMOMERIC GIRK2 CHANNELS BY CHOLESTEROL. James T. Pentikis , Ana Santa Cruz, Yongcheng Lu, Liang Wang, Takeharu Kawano, Mehreen Zaka, Nousheen Parvaiz, Frank Guarnieri, Diomedes E. Logothetis, Georgios Skiniotis, Meng Cui 1105-Pos Board B279 Travel Award Winner USING TRANSITION METAL FRET TO PROBE PIP 2 -MEDIATED GATING IN TMEM16A. Jennifer M. Miller , Kloee Connelly, Anne E. Carlson 1106-Pos Board B280 INVESTIGATION OF ION CHANNEL RESPONSES TO NANOSECOND PULSED ELECTRIC FIELDS. Nina Reitano Ferber , Patricia Nabos, Flor ence Poulletier De Gannes, Annabelle Hurtier, André Garenne, Isabelle Lagroye, Rosa Orlacchio, Yann Percherancier 1107-Pos Board B281 ANTIARRHYTHMIC EFFECTS OF MIRABEGRON ON VENTRICULAR FIBRIL LATION IN LANGENDORFF-PERFUSED HFPEF FEMALE RABBIT VENTRI CLES. Minjing Yang , Liyang Zhang, Po-Tseng Lee, Anxhela Kote, James E. Tisdale, Zhenhui Chen, Peng-Sheng Chen, Xiao Liu 1108-Pos Board B282 Travel Award Winner A RYANODINE RECEPTOR 2 VARIANT EXPRESSED IN RBM20-MUTANT MICE SHOWS ALTERED FUNCTIONAL AND BIOPHYSICAL PROPER TIES. Sergio Estrada , Yanghai Zhang, Wei Guo, Francisco J. Alvarado 1109-Pos Board B283 Travel Award Winner CORRELATED PORE FLUCTUATIONS IN CONDUCTING STATES OF ION CHANNELS FROM ASTROCYTES. Katerin G. Pimentel-Granados , J. Rafael Godínez Fernández, Paola M. Vazquez-Vazquez, Mina Konigsberg Fain stein, Adriana Alarcón-Aguilar, Gerardo J. Felix-Martínez 1110-Pos Board B284 PIP2 ACTIVATES SK CHANNELS BY A SIMILAR MECHANISM ACROSS ALL KNOWN ISOFORMS. Ryan L. Woltz , Nipavan Chiamvimonvat, Dolores Columba Perez-Flores, Woori Choi, Igor V. Vorobyov, Yang Zheng, Ebene zer N. Yamoah 1111-Pos Board B285 Travel Award Winner SECONDARY STRUCTURE TRANSITIONS DEFINE CARDIAC KCNQ1-KCNE1 CHANNEL GATING. Ling Zhong, Xiaoqin Lin, Xinyu Cheng, Shuangyan Wan, Jin Zhang, Panpan Hou

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