BPS2026 Program Book

1772-Pos Board B309 STRUCTURAL BASIS OF COLD AND MENTHOL SENSING BY TRPM8. Hyuk Joon Lee , Cheon-Gyu Park, Justin G. Fedor, Wyatt A. Peele, Mario J. Borgnia, Seok-Yong Lee 1773-Pos Board B310 Travel Award Winner FUNCTIONAL AND STRUCTURAL BASIS OF A TRPC3-MEDIATED CEREBEL LAR ATAXIA. Briar Bell , Angela M. Jaramillo Granada, Luis O. Romero, Irene A. Gutierrez, Venkata K.P.S. Mallampalli, Guizhen Fan, Sameer Varma, Matthew L. Baker, Irina I. Serysheva, Valeria Vásquez, Julio F. Cordero-Morales Membrane Pumps, Transporters, and Exchangers II (Boards B311 - B328) 1774-Pos Board B311 FURTHER CHARACTERIZATION OF LEAKY ATP1A1 VARIANTS CAUSING HYPOMAGNESEMIA WITH SEIZURES. Nicolas G. Colmano , Daniel Self, Kazuhiro Abe, Pablo Artigas 1775-Pos Board B312 ACTIVITY OF MITOCHONDRIAL TRANSPORTER ABCB25 FROM ARA BIDOPSIS THALIANA IS STIMULATED BY SULFUR-CONTAINING MOL ECULES. Annabella Nouel Barreto , Maria E. Zoghbi 1776-Pos Board B313 PROTONATION-DEPENDENT UPTAKE AND EMERGENT CHLORIDE GAT ING UNDERPIN FLUORIDE SELECTIVITY IN CLCF F⁻/H⁺ANTIPORTER. Akihiro Y. Y Nakamura , Takuya Mabuchi 1777-Pos Board B314 SSME RESOLVES THREE GABA-INDUCED ELECTROGENIC EVENTS AND GABA-COUPLING STOICHIMETRY FOR NA + AND CL - IN HGAT1. Rocco Zerlotti , Andre Bazzone, Maria Barthmes 1778-Pos Board B315 ROLE OF THE IDENTICAL NUCLEOTIDE BINDING DOMAINS IN THE E. COLI ABC TRANSPORTER METNI-Q. Maile Gardner 1779-Pos Board B316 PATHWAY CHARACTERIZATION OF THE DOPAMINE TRANPOSTER VIA MILESTONING OF TARGETED MOLECULAR DYNAMICS. Mayar T. Mohamed , Pengyu Ren 1780-Pos Board B317 CONFORMATIONAL EQUILIBRIUM OF AN ABCB10 SUBSTRATE-BINDING POCKET MUTANT THAT DISPLAYS CONSTITUTIVELY ELEVATED ATP HYDROLYSIS RATE. Maria E. Zoghbi , Alex L. Hernandez, Annabella Nouel Barreto, Valeria Arellano Haro 1781-Pos Board B318 KNOCKDOWN OF MICROPEPTIDE “ANOTHER-REGULIN” IS PROTECTIVE AGAINST OXIDATIVE STRESS IN NEURONS. Emily Neeb 1782-Pos Board B319 MOLECULAR MECHANISM OF K + COUPLING IN A GLUTAMATE TRANS PORTER. Ashkan Fakharzadeh , Emad Tajkhorshid 1783-Pos Board B320 THE C-TERMINAL PDZ-BINDING MOTIF OF CX40 IS REGULATED BY PHOS PHORYLATION AND REQUIRED FOR THE FORMATION OF FUNCTIONAL INTERCELLULAR CHANNELS. Luya Wei , Nishant Sharma, Ben Bridgelal, Curtis Furukawa, Aiden Momtaz, Jingyi Shirley Xie, Sofia Endzhievskaya, Irina Kufareva

1784-Pos Board B321 CYTOTOXICITY OF THE ORGANIC CATION TRANSPORTER (OCT3) INHIBI TOR DECYNIUM-22 ENHANCED BY ACTIVATION OF K CA 3.1 CHANNELS IN CERVICAL CANCER SPHEROIDS. Norman C. Haaker , Min Htwe, Creighton Williams, Shantanu Sur, Damien Samways 1785-Pos Board B322 MOLECULAR INSIGHTS INTO MITOCHONDRIAL CALCIUM EXTRU SION. Aswini R. Krishnan , Minrui Fan, Chen-Wei Tsai, Jinru Zhang, Jianxiu Zhang, Ming-Feng Tsai, Liang Feng 1786-Pos Board B323 STRUCTURE-GUIDED DESIGN FOR NBCN2: ROUTES TO SELECTIVE INHI BITION. Lasse M. Desdorf , Amanda D. Stange, Nicoline S. Jensen, Helle H. Damkier, Birgit Schiøtt, Jeppe Praetorius, Anna L. Duncan 1787-Pos Board B324 LIPIDS PLAY A FUNCTIONAL ROLE IN THE POTASSIUM TRANSPORT BY KDPFABC. Adel K. Hussein , Xihui Zhang, David L. Stokes 1788-Pos Board B325 MECHANISTIC INSIGHTS INTO GLUCOSE TRANSPORT FOR PFHT1 FROM MOLECULAR DYNAMICS AND GRAPH ATTENTION MODELS. Arnav Paul , Diwakar Shukla 1789-Pos Board B326 Travel Award Winner STRUCTURE AND FUNCTIONAL CHARACTERIZATION OF THE HUMAN PROSTAGLANDIN TRANSPORTER (PGT). Peixuan Yu , Melanie A. Orlando, Benjamin J. Orlando 1790-Pos Board B327 BILATERAL LIPID WEDGES SHAPE OUTWARD DRUG RELEASE: MOLECU LAR DYNAMICS INSIGHTS INTO THE OUTWARD FACING STATES OF THE HETERODIMERIC ABC EXPORTER. Yunsen Zhang , Emad Tajkhorshid 1791-Pos Board B328 STRUCTURE AND DYNAMICS OF CORA MG 2+ ION CHANNEL FROM MYCOBACTERIUM TUBERCULOSIS IN NATIVE NANODISCS​. Roshan R. Pathak , Madolyn Britt, Nicholas D. Clark, Peter R. Johnson, Fei Zhou, Elissa Moller, Alexander J. Sodt, Doreen Matthies Mechanosensitive Ion Channels (Boards B329 - B341) 1792-Pos Board B329 UNDERSTANDING THE ROLE OF F127 IN MSCS GATING. Keilah Adams, Jessica Galub, Hannah R. Malcolm 1793-Pos Board B330 CONTRIBUTION OF THE PERIPLASMIC LOOP TO MECHANOSENSITIVITY OF MSCL, THE E. COLI MECHANOSENSITIVE CHANNEL OF LARGE CON DUCTANCE. Kingsley C. Duru 1794-Pos Board B331 NEGATIVELY CHARGED AMINO ACIDS OF ASYMMETRIC LIPID-PROTEIN VESICLES AFFECT MECHANOSENSITIVE CHANNEL FUNCTION. Kotaro Baba , Koki Kamiya 1795-Pos Board B332 POTENTIAL ROLE FOR THE TMC5-CIB COMPLEX IN COUPLING MEM BRANE MECHANICS TO CALCIUM INFLUX DURING SPERM DEVELOP MENT. Wenxuan (Sharon) Zheng , Christopher Geyer, Brian Hermann, Seham Ebrahim 1796-Pos Board B333 MOLECULAR INSIGHTS INTO CALCIUM-REGULATED CIB2-TMC1/2 INTER ACTIONS AND THEIR IMPLICATIONS FOR INNER-EAR MECHANOTRANS DUCTION. Wei-Hsiang Weng , Marcos M. Sotomayor

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