BPS2026 Program Book

Structure, Dynamics, and Function of Organelles (Boards B182 - B199) 2224-Pos Board B182 4D MITOCHONDRIAL NETWORK ASSUMES DISTINCT AND PREDICTIVE PHENOTYPES THROUGH HUMAN LUNG AND INTESTINAL EPITHELIAL DEVELOPMENT. Gillian McMahon , Dhruv Agarwal, Mehul Arora, Zichen Wang, Hiroyuki Hakozaki, Johannes Schöneberg 2225-Pos Board B183 MOLECULAR ARCHITECTURE OF KICSTOR IN LYSOSOMAL MEMBRANE TARGETING AND MTORC1 CONTROL. MIng-Yuan Su 2226-Pos Board B184 INVESTIGATING MALARIA PARASITE MEMBRANE CONTACT SITE DO MAIN COARSENING AND BOUNDARY FLUCTUATIONS. Kyle McLelland , Matthias Garten 2227-Pos Board B185 IN VITRO GENERATED NEUTROPHILS REVEAL HIGH DEFORMABILITY IS AN EMERGENT PROPERTY. Allen Yesin , Regina Sanchez Flores, Hawa Racine Thiam 2228-Pos Board B186 NUCLEAR DEFORMATIONS AND EPIGENOMIC REMODELING DURING MATURATION OF A HUMAN EPIBLAST MODEL. Alex Esclamado , Dhiraj Indana, Junqin Zhu, Michael Bassik, Nidhi Bhutani, Ovijit Chaudhuri 2229-Pos Board B187 DIRECT VISUALIZATION OF PEROXISOME BIOGENESIS USING LIVE-CELL SINGLE-MOLECULE TRACKING. Dean Boecher , Christopher J. Obara 2230-Pos Board B188 THE ENDOPLASMIC RETICULUM AS AN INTRACELLULAR TRANSPORT HUB - FROM CONTACT SITES TO CA²⁺ REFILL. Yuyi Zhang , Valentina Davi, Edward Avezov, Elena F. Koslover 2231-Pos Board B189 DIFFUSIVE SPREADING ON DYNAMIC, SOLID AND LIQUID MITOCHON DRIAL NETWORKS. Keaton B. Holt , Camryn Zurita, Lizzy Teryoshin, Samantha C. Lewis, Elena F. Koslover 2232-Pos Board B190 SEVERING OF MITOCHONDRIA-MIMICKING MEMBRANE TETHERS BY DRP1 DEPENDS ON MFF. Yannic Lurz , Steven Jocksch, Theresa Fröhlich, Ulrich Rothbauer, Erik Schäffer 2233-Pos Board B191 ALGEBRAIC APPROACH TO REPRESENTING MITOCHONDRIAL DYNAMICS LEADS TO NEW SIMILARITY MEASURE AND POTENTIAL EVIDENCE OF REGULATORY MECHANISMS. Raphael I. Mostov , Greyson Lewis, Gabriel Sturm, Wallace Marshall 2234-Pos Board B192 STRUCTURE OF PEX8 IN COMPLEX WITH PEROXISOMAL SHUTTLING RECEPTOR PEX5 REVEALS ITS ESSENTIAL ROLE IN CARGO TRANSLOCA TION. Matthias Wilmanns 2235-Pos Board B193 Travel Award Winner A TUNABLE SYNTHETIC TOOL TO SEQUESTER ORGANELLES VIA BIOMO LECULAR CONDENSATES. Liting Zhou , Shankar Mukherji 2236-Pos Board B194 PTPIP51 MEDIATES MITOCHONDRIAL-SARCOPLASMIC RETICULUM AP PROXIMATION AFTER MYOCARDIAL INFARCTION. An Xie , Gyeoung-Jin Kang, Eun Ji Kim, Samuel C. Dudley

2237-Pos Board B195 ESPRESSO: SPATIOTEMPORAL OMICS BASED ON ORGANELLE PHENO TYPING REVEALS DYNAMIC CELL STATE TRANSITIONS. Lorenzo Scipioni , Giulia Tedeschi, Mariana Navarro, Yunlong Jia, Songning Zhu, Lila P. Hal bers, Melody Di Bona, Scott Atwood, Jennifer Prescher, Enrico Gratton, Michelle A. Digman 2238-Pos Board B196 SPATIO-TEMPORAL DYNAMICS OF ACTIVE AND PASSIVE NUCLEO CYTOPLASMIC TRANSPORT IN LIVE HUMAN CELLS. Sumon Sahu , Alexis S. Clavijo, Isabel N. Brown, Nancy Shi, Dominic Krusniak, Alexandra Zidovska 2239-Pos Board B197 DETERMINING MECHANISMS UNDERLYING NUCLEAR SIZE CONTROL IN FISSION YEAST. Joël Lemiere , Fred Chang 2240-Pos Board B198 INVESTIGATING DNA DAMAGE AS A FUNCTION OF VARYING RADIATION DOSE RATES ON NORMAL AND MALIGNANT MAMMARY EPITHELIAL CELLS. Simruthi Subramanian , Savannah Kidd, Natalia Molchanova, Behzad Rad, Jared de Chant, Aodhan McIlvenny, Anthony Lu, Kei Naka mura, Lieselotte Obst-Huebl, Corie Y. Ralston, Jamie Inman 2241-Pos Board B199 DIRECT VISUALIZATION OF ER-ASSOCIATED DEGRADATION BY MULTI COLOR SINGLE MOLECULE TRACKING. Tim Abel , Lilly Castorena, Bran don M. Liu, Sonya E. Neal, Christopher J. Obara Ligand-Gated Channels (Boards B200 - B220) 2242-Pos Board B200 STRUCTURAL BASIS OF LIGAND SELECTIVITY AND GATING IN RHO-TYPE GABAA RECEPTORS. Chen Fan, John Cowgill, Rebecca J. Howard, Erik Lindahl 2243-Pos Board B201 EFFECTS OF BUPROPION ON SYNAPTIC AND EXTRASYNAPTIC GABA A RE CEPTORS. Lauren E. Anderson , Quynh Hoa Do, Michaela Jansen 2244-Pos Board B202 MECHANISTIC ROLE OF SURFACE GLYCOSYLATION IN NEUROTRANS MITTER BINDING AND GATING OF GABA A RECEPTORS. Amin Akbari Ahangar , Jing Li 2245-Pos Board B203 TARP Γ8 LOOP CONTROLS AMPAR ALLOSTERIC DRUG ACTIONS. Josip Ivica , Ingo Greger 2246-Pos Board B204 INTERROGATING EXTRACELLULAR UNSTRUCTURED DOMAINS OF AMPA RECEPTOR AUXILIARY PROTEINS USING FRET. Jonathan J. Stallone , Tyler A. Couch, David M. MacLean 2247-Pos Board B205 SINGLE-MOLECULE IMAGING OF AMPARS WITH NONCOMPETITIVE IN HIBITORS BY HIGH-SPEED AFM. Mikihiro Shibata , Keisuke Sato, Yimeng Zhao, Motoyuki Hattori 2248-Pos Board B206 SINGLE MOLECULE FRET REVEALS GLYCINE- AND ANTAGONIST- DEPEN DENT CONFORMATIONAL DYNAMICS OF NMDA RECEPTORS. Geetika Verma , Vladimir Berka, Ashish Apotikar, Vasanthi Jayaraman 2249-Pos Board B207 EXPLORING HETEROMERIC 5-HT 3 RECEPTOR PAIRINGS USING FRET AND FIR. Stella Garson , Michael C. Puljung

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