Biophysical Society 2020 Annual Meeting

1011-Pos Board B79 LONG RANGE CORRELATED MOTIONS OF TIM AND THEIR POSSIBLE INFLUENCE ON ENZYME FUNCTION. Jeffrey A. McKinney, Yanting Deng, Deepu K. George, John Richard, Andrea G. Markelz 1012-Pos Board B80 RESOLVING FREE-ENERGY CONTRIBUTIONS OF SUBSTRATE DELIVERY TO DESATURASE BY ATOMISTIC SIMULATIONS. Marcel D. Baer , Simone Raugei 1013-Pos Board B81 USING MOLECULAR SIMULATIONS TO INFORM DRUG DEVELOPMENT EFFORTS FOR THE GPCR CCR2. Bryn C. Taylor , Christopher T. Lee, Rommie Board B82 FREE ENERGY LANDSCAPE OF CASEIN KINASE DELTA AND ITS IMPLICA- TIONS FOR CIRCADIAN RHYTHM. Clarisse Gravina Ricci , Jonathan M. Philpott, Rajesh Narasimamurthy, Alfred M. Freeberg, Sabrina R. Hunt, Lauren E. Yee, Rebecca S. Pelofsky, Sarvind Tripathi, David M. Virshup, Carrie L. Partch 1015-Pos Board B83 MODELLING AND PREDICTING ALLOSTERY WITH PROPAGATION OF RIGIDITY ACROSS PROTEIN STRUCTURES. Adnan Sljoka 1016-Pos Board B84 EVIDENCE OF INTRAMOLECULAR STRUCTURAL STABILIZATION IN LIGHT ACTIVATED STATE OF ORANGE CAROTENOID PROTEIN.  Jeffrey A. McKinney , Akansha Sharma, Kimberly Crossen, Yanting Deng, Deepu K. George, Sigal Lechno-Yossef, Cheryl Kerfeld, Andrea G. Markelz 1017-Pos Board B85 COMBINING LE4PD NORMAL MODES AND MARKOV STATE MODELING TO ELUCIDATE THE FLUCTUATION DYNAMICS OF UBIQUITIN.  Eric R. Beyerle , Marina G. Guenza 1018-Pos Board B86 INVESTIGATING FULL-LENGTH P53 TETRAMER DYNAMICS WITH MULTI- MICROSECOND MOLECULAR DYNAMICS SIMULATIONS. Ozlem Demir , Rommie E. Amaro 1019-Pos Board B87 ALLOSTERY EXPLAINED THROUGH SYNCHRONIZED OSCILLATORS AND FRACTAL NETWORKS. Alexandr P. Kornev Membrane Protein Structures I (Boards B88 - B107) 1020-Pos Board B88 STRUCTURE AND TOPOLOGY OF THE SERCA REGULATOR DWORF IN LIPID BILAYERS BY ORIENTED SAMPLE SOLID-STATE NMR. Venkateswara Reddy Uddigiri , Daniel Weber, Songlin Wang, Erik K. Larsen, Seth L. Robia, Gianluigi Veglia 1021-Pos Board B89 EXPRESSION OF FUNCTIONAL HUMAN NA + - COUPLED CITRATE TRANS- PORTER (SLC13A5) IN THE YEAST PICHIA PASTORIS .  Valeria Jaramillo-Martinez , Ina L. Urbatsch, Vadivel Ganapathy 1022-Pos Board B90 STUDY THE STRUCTURAL TOPOLOGY, DYNAMIC PROPERTIES AND FUNC- TIONAL MODEL OF PHAGE 21 HOLIN PROTEIN USING EPR SPECTROS- COPY. Tanbir Ahammad , Daniel L. Drew, Indra Sahu, Rasal Khan, Tianyan Li, Emily Faul, Robert M. McCarrick, Gary A. Lorigan 1023-Pos Board B91 Travel Awardee PROBING THE M1-M2 INTERACTION IN INFLUENZA A VIRUS USING SITE- DIRECTED SPIN LABELING EPR IN LIPID BILAYER NANODISCS.  Elizabeth Erler , RehamMahgoub, Kathleen P. Howard E. Amaro 1014-Pos

1024-Pos Board B92 EPR DISTANCE MEASUREMENTS ON THE E. COLI COBALAMIN TRANS- PORTER BTUB INDICATE CONFORMATION AND ORGANIZATION ARE DEPENDENT ON THE NATIVE, CELLULAR ENVIRONMENT. David Nyenhuis , Thushani D. Nilaweera, David S. Cafiso 1025-Pos Board B93 Travel Awardee SELF-ASSEMBLY OF E5/PDGFΒR IN MEMBRANES STUDIED BY SOLID-STATE NMR DISTANCE MEASUREMENTS. Li Tian , Stephan L. Grage, Parvesh Wadhwani, Anne S. Ulrich 1026-Pos Board B94 Travel Awardee STRUCTURAL ANALYSIS OF A PHOSPHATE ‘TRANSCEPTOR’.  Meghna Gupta , Robert M. Stroud 1027-Pos Board B95 INVESTIGATION OF STRUCTURAL TOPOLOGY AND DYNAMICS OF CANON- ICAL HOLIN IN LIPOSOMES USING EPR SPECTROSCOPY.  Indra D. Sahu , Rehani S. Perera, Ryan Kaplevatsky, Jack Bennett, Gary A. Lorigan 1028-Pos Board B96 INFLUENCES OF A NEAR-NATIVE MEMBRANE ENVIRONMENT ON THE STRUCTURE AND FUNCTION OF THE YERSINIA PESTIS OUTER MEMBRANE PROTEIN AIL.  James E. Kent , L. Miya Fujimoto, Yong Yao, Kyungsoo Shin, Chandan Singh, Francesca M. Marassi 1029-Pos Board B97 FROM THE GRAM-NEGATIVE BACTERIAL EXTRACELLULAR SPACE TO PERI- PLASMIC SPACE WITH EPR: EXPLORING THE ESCHERICHIA COLI VITAMIN B 12 TRANSPORTER, BTUB, IN WHOLE CELLS. Thushani D. Nilaweera , David A. Nyenhuis, Robert K. Nakamoto, David S. Cafiso 1030-Pos Board B98 THE ROLE OF PROTEIN-LIPID INTERACTIONS IN THE FUNCTIONING OF BITOPIC MEMBRANE PROTEINS. Eduard V. Bocharov , Dmitry M. Lesovoy, Olga V. Bocharova, Anatoly S. Urban, Yaroslav V. Bershacky, Pavel E. Volyn- sky, Roman G. Efremov, Alexander S. Arseniev 1031-Pos Board B99 MEMBRANE-MEDIATED CONFORMATIONAL CHANGES OF CYTOPROTEC- TIVE BCL-XL REGULATE ITS ACTIVITY. Pavel Ryzhov , Yong Yao, Betsaida Bibo Verdugo, Guy Salvesen, Francesca M. Marassi 1032-Pos Board B100 CONFORMATIONAL SAMPLING OF PH-LOW INSERTION PEPTIDES IN MUL- TICOMPONENT BILYAYERS: EFFECTS OF CHARGED LIPIDS AND PROTON- ATION STATES. Brandon M. Bogart , Afra Panahi 1033-Pos Board B101 CRYO-EM STRUCTURE OF RICE OSCA1.2 ELUCIDATES THE MECHANICAL BASIS OF MEMBRANE HYPEROSMOLALITY GATING IN PLANTS. Koustav Maity , John M. Heumann, Aaron P. McGrath, Noah J. Kopcho, Po-Kai Hsu, Srinivasan Krishnan, Arturo Medrano-Soto, Milton H. Saier, Miguel A. Pi- ñeros, Elizabeth A. Komives, Julian I. Schroeder, Geoffrey Chang, Michael H.B. Stowell 1034-Pos Board B102 STRUCTURE-FUNCTION STUDIES OF THE Α4Β2 NICOTINIC ACETYLCHO- LINE RECEPTOR IN A LIPIDIC ENVIRONMENT. Guipeun Kang 1035-Pos Board B103 Travel Awardee CHOLESTEROL CONTROLS DYNAMICS OF THE METABOTROPIC GLUTA- MATE RECEPTOR 2 VIA AN IONIC-LOCK. Angelica Sandoval-Perez 1036-Pos Board B104 STRUCTURAL MODELING OF THE HERG CHANNEL IN AN INACTIVATED STATE AND ASSOCIATED DRUG INTERACTIONS.  Jan Maly , Aiyana M. Emigh, Kevin DeMarco, Jon T. Sack, Igor V. Vorobyov, Colleen E. Clancy, Vladimir Yarov-Yarovoy

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