Biophysical Society 2020 Annual Meeting

DNA Structure and Dynamics II (Boards B132 - B152)

1078-Pos Board B146 POLARIZABLE MOLECULAR DYNAMICS SIMULATIONS OF DNA G-QUA- DRUPLEXES REVEAL DIFFERENT PROPERTIES OF NUCLEOBASE ELECTRON- IC STRUCTURE AND CATION BINDING.  Justin A. Lemkul 1079-Pos Board B147 IRREVERSIBILITY OF CONFORMATIONAL CHANGES AND ZN 2+ BINDING TO DNA. Kurt Andresen , Olivia Peduzzi, Claire Woodward, Katie Madore, Shelli L. Frey, Katherine M. Buettner 1080-Pos Board B148 DNA ELECTROPHORETIC MOBILITIES IN HIGH IONIC STRENGTH SOLU- TIONS. Nancy C. Stellwagen , Earle Stellwagen 1081-Pos Board B149 BIOMIMETIC TRANSMEMBRANE SIGNAL TRANSDUCING DNA NANOSEN- SOR FOR MEMBRANE ENCLOSED NUCLEIC ACID BIOMARKER DETEC- TION. Swarup Dey , Alonzo Beatty V, Hao Yan 1082-Pos Board B150 DNA DIELECTRIC AND ELECTROMAGNETIC PROPERTIES- THEORETICAL BACKGROUND, EXPERIMENTAL FINDINGS AND DISCUSSION. Masroor H.S. Bukhari , Asifa Bukhari, Salma Batool, Yasir Raza, Tashmeem Razzaki 1083-Pos Board B151 COARSE-GRAINED MODELING OF DNA PLECTONEME FORMATION IN THE PRESENCE OF BASE-PAIR MISMATCHES. Parth Rakesh Desai , Siddhartha Das, Keir C. Neuman 1084-Pos Board B152 TESTING THE RETROELEMENT INVASION HYPOTHESIS FOR THE EMER- GENCE OF THE ANCESTORAL EUKARYOTIC CELL. Davneet Kaur , Gloria Lee, Nicholar Sherer, Neil H. Kim, Elliot Urriola, Michael Martini, Chi Xue, Nigel Goldenfeld, Thomas E. Kuhlman Protein-Nucleic Acid Interactions II (Boards B153 - B177) 1085-Pos Board B153 USING PROGRAMMABLE ROADBLOCKS TO PROBE DNA TARGET SEARCH. Allen C. Price 1086-Pos Board B154 SINGLE-MOLECULE STUDIES OF DOXORUBICIN-DNA INTERACTIONS USING OPTICAL TWEEZERS. Zachary Ells , Brian Dolle, Mark C. Williams, Thayaparan Paramanathan 1087-Pos Board B155 COOPERATIVITY AND COMPETITION IN THE BINDING OF HETEROCYCLIC DIAMIDINES AND RNA POLYMERASES TO PHIX174 DNA. Stephen A. Winkle , Rosalina Fernandez-Paradas, Selma Hernandez, Erney Lorquet, Stephanie Singer, Nidia Rodriguez 1088-Pos Board B156 BIOPHYSICAL STUDIES OF NON-CODING RNAS. Tyler Mrozowich, Darren L. Gemmill, Corey R. Nelson, Michael H. D’souza, Maulik Badmalia, Van- essa Meier-Stephen, Trushar R. Patel 1089-Pos Board B157 EVIDENCE THAT PRIMARY MICRORNA BENDS IN THE PRESENCE OF DGCR8 SEEN USING BOTH SAXS AND FRET MEASUREMENTS. Suzette A. Pabit , Yen-Lin Chen, Grace A. Usher, Erik C. Cook, Lois Pollack, Scott A.

M O N D A Y

1064-Pos Board B132 MOLECULAR CROWDING EFFECTS ON STABILITY AND KINETICS OF TRINU- CLEOTIDE REPEAT HAIRPINS. Deema Martini, Brian L. Cannon 1065-Pos Board B133 ACCURATE ASSESSMENT OF BIOMOLECULAR PARTIAL SPECIFIC VOLUMES FROM POLARIZABLE MD SIMULATIONS AND ANALYTICAL ULTRACENTRI- FUGATION EXPERIMENTS. Alexey Savelyev , Borries Demeler 1066-Pos Board B134 CALCULATING THE BINDING FREE ENERGY DIFFERENCE BETWEEN CONFORMATIONAL CHANGES OF AT-RICH DNA SEQUENCES. Md Lokman Hossen , Prem P. Chapagain, Bernard Gerstman 1067-Pos Board B135 REAL-TIME CONDENSATION OF NANOCONFINED DNA BY AN INTRINSI- CALLY DISORDERED POLYCATIONIC PROTEIN. Rajhans Sharma , Sriram KK, Erik D. Holmstrom, Fredrik Westerlund 1068-Pos Board B136 LABEL-FREE SINGLE-MOLECULE QUANTIFICATION OF DNA BY MASS PHO- TOMETRY. Yiwen Li , Weston B. Struwe, Katharina Häußermann, Philipp Kukura 1069-Pos Board B137 STUDYING THE INTRAMOLECULAR FORCES OF BASE-MODIFIED NUCLEIC ACIDS USING OPTICAL TWEEZERS. Vinoth Edal Joseph Sundar Rajan , Xavier Viader, Yii-Lih Lin, Felix Ritort, Fredrik Westerlund, Marcus Wil- Board B138 ATOMIC FORCE MICROSCOPY STUDY OF INTERCALATED DNA MOL- ECULES.  Joseph Tibbs , S. M. Ali Tabei, Timothy E. Kidd, Justin P. Peters 1071-Pos Board B139 DIRECT MEASUREMENT OF FLUID SHEAR STRESS IN 3-D MATRICES USING DNA-BASED FORCE SPECTROSCOPY. Peter E. Beshay , Kelly L. Kolotka, Jonathan W. Song, Carlos E. Castro 1072-Pos Board B140 Travel Awardee MEMORY EFFECTS IN SINGLE-MOLECULE FORCE SPECTROSCOPY MEA- SUREMENTS OF BIOMOLECULAR FOLDING. Andrew G. Pyo , Michael T. Board B141 NANOPORE-BASED ANALYSIS OF CONFORMATIONAL HETEROGENEITY OF NUCLEIC ACIDS USING A GAMMA-HEMOLYSIN PROTEIN CHANNEL.  Cherie S. Tan 1074-Pos Board B142 A DEEP DIVE INTO DNA BASE PAIRING INTERACTIONS UNDER WA- TER. Rongpeng Li , Chi H. Mak 1075-Pos Board B143 COUNTERION CONDENSATION ON A POLYELECTROLYTE UNDER EXTER- NAL ELECTRIC FIELDS. Pyeong Jun Park 1076-Pos Board B144 INFLUENCE OF MONOVALENT CATIONS ON THE DYNAMICS OF THE C-KIT1 PROMOTER G-QUADRUPLEX USING POLARIZABLE MOLECULAR DYNAMICS SIMULATIONS. Alexa M. Salsbury , Justin A. Lemkul 1077-Pos Board B145 FOLDING/UNFOLDING PATTERN AND STABILITY OF INTRAMOLECULAR G-QUADRUPLEX STRUCTURE BY MYOINOSITOL. Danish Idrees helmsson 1070-Pos Woodside 1073-Pos

Showalter 1090-Pos

Board B158 VIRAL RNA FOLDING STUDIED THROUGH CONTRAST VARIATION SMALL ANGLE- X RAY SCATTERING.  Josue San Emeterio , Lois Pollack

79