Biophysical Society 2020 Annual Meeting

2132-Pos Board B402 Travel Awardee UNCOVERING THE MOLECULAR AND STRUCTURAL BASIS OF HYPER- TROPHIC CARDIOMYOPATHY-CAUSING MUTATIONS IN MYOSIN AND MYOSIN BINDING PROTEIN-C. Neha Nandwani , Darshan V. Trivedi, Saswata S. Sarkar, Makenna Morck, Kathleen Ruppel, James A. Spudich 2133-Pos Board B403 Travel Awardee STUDY OF HCM CAUSING Β-CARDIAC MYOSIN MUTATIONS LOCATED AT DIFFERENT STRUCTURALLY SIGNIFICANT REGIONS OF THE MYOSIN- HEAD. Debanjan Bhowmik , Neha Nandwani, Kathleen Ruppel, Chao Liu, James A. Spudich 2134-Pos Board B404 AUTO-INHIBITION OF ACTIN-MYOSIN ATPASE THROUGH COLLECTIVE FORCE GENERATION. Vidya Murthy , Travis J. Stewart, Christine R. Cremo, Josh E. Baker 2135-Pos Board B405 THE DIRECT MEASUREMENT OF THE STEPPING FORCE OF A PURIFIED VESICLE USING A SINGLE BEAM OPTICAL TRAP.  Justin J. Raupp , Takeshi Board B406 COMPUTATIONAL STUDY OF THE EFFECT OF POINT MUTATIONS PER- TURBING THE RECOVERY STROKE OF HUMAN CARDIAC BETA-MYOSIN USING METADYNAMICS. Ananya Chakraborti , Jil C. Tardiff, Steven D. Board B407 BUFFER EXCHANGE WHILE PROBING A SINGLE ACTOMYOSIN INTERAC- TION IN THE OPTICAL TRAP. Aaron Snoberger , Donald A. Winkelmann, E. Michael Ostap, Yale E. Goldman 2138-Pos Board B408 COMPUTATIONAL EVALUATION OF POINT MUTATION PERTURBATIONS TO THE RECOVERY STROKE OF DICTYOSTELIUM MYOSIN II WITH META- DYNAMICS. Anthony P. Baldo , Jil C. Tardiff, Steven D. Schwartz 2139-Pos Board B409 REDUCED BETA MYOSIN HEAVY CHAIN K213 ACETYLATION AND T215 PHOSPHORYLATION IN HUMAN HEART FAILURE. Amanda Wacker, Michelle C. Rodriguez Garcia , Maicon Landim Vieira, Rakesh K. Singh, Elizabeth A. Brundage, Bryan A. Whitson, Paul M. Janssen, Prescott B. Chase, Brandon J. Biesiadecki, Michelle S. Parvatiyar, J. Renato D. Pinto 2140-Pos Board B410 ACTIN NETWORK ORGANIZATION BY THE MONOMERIC MYOSIN IXA. Markus Kröss , Dario Saczko-Brack, Christopher Batters, Claudia Veigel 2141-Pos Board B411 A LANDSCAPE-BASED VIEW ON THE STEPPING MOVEMENT OF MYOSIN VI. Tomoki P. Terada , Qing-Miao Nie, Masaki Sasai 2142-Pos Board B412 UTILIZATION OF TRANSITION PATH SAMPLING TO PERFORM DYNAMI- CALLY UNBIASED SIMULATIONS OF ATP HYDROLYSIS IN TWO ISOFORMS OF MYOSIN II. Ananya Chakraborti , Anthony Baldo, Jil C. Tardiff, Steven D. Schwartz Cytoskeletal Assemblies and Dynamics (Boards B413 - B429) 2143-Pos Board B413 MODELING ACTIN NETWORKS IN REALISTIC GEOMETRIES OF DENDRITIC SPINES. Andrew Nguyen , Justin L. Oshiro, Christopher T. Lee, Michael Holst, Padmini Rangamani 2144-Pos Board B414 PRIMARY CILIUM SUBMICRON ORGANIZATION AND DYNAMICS. Belén Torrado , Lorenzo Scipioni, Enrico Gratton, José L. Badano, Leonel S. Malacrida, Florencia Irigoín Sakamoto 2136-Pos Schwartz 2137-Pos

2145-Pos Board B415 THE EFFECTS OF X-RAY CONTRAST MEDIA ON ACTIN. Gábor Hild, Elek Telek, Zoltan Ujfalusi 2146-Pos Board B416 MECHANISMS UNDERLYING NWASP ACTIVATION BY SYNERGISTIC PAIRS OF SIGNALING MOLECULES. Aniruddha Chattaraj , Leslie M. Loew 2147-Pos Board B417 INTERCELLULAR FORCE TRANSMISSION IN WOUND CLOSURE. Ai Kia Yip, Keng-Hwee Chiam 2148-Pos Board B418 MECHANICAL FORCE-DRIVEN REGISTRY OF NON-MUSCLE MYOSIN IN FIBROBLASTS. Kinjal Dasbiswas , Shiqiong Hu, Alexander D. Bershadsky, Samuel Safran 2149-Pos Board B419 SLIDING FILAMENT AND FIXED FILAMENT MECHANISMS CONTRIB- UTE TO TENSION OF THE FISSION YEAST CYTOKINETIC RING. Roberto Alonso-Matilla , Sathish Thiyagarajan, Ben O’Shaughnessy 2150-Pos Board B420 REAL TIME AFM IMAGING OF DEPOLYMERIZING MICROTUBULE ARRAYS AT SINGLE PROTOFILAMENT RESOLUTION. Radhika Subramanian , Sithara Wijeratne 2151-Pos Board B421 BENDING OF ACTIN FILAMENTS INTO RINGS BY IQGAP FAMILY OF PROTEINS. Saravanan Palani, Tzer Chyn Lim, Mohan K. Balasubramanian, Darius V. Koester 2152-Pos Board B422 DYNAMICS OF FORCE-REGULATED BRANCHED ACTIN NETWORK DEN- SITY. Tai-De Li , Peter Bieling, Dyche Mullins, Daniel A. Fletcher 2153-Pos Board B423 CHANGE IN THE HELICAL SYMMETRY OF CHLAMYDOMONAS AND CIONA FLAGELLAR AXONEMES COUPLED WITH THE CHANGE IN CA 2+ CONCENTRATIONS REVEALED BY X-RAY FIBER DIFFRACTION. Kazuhiro Oiwa , Hiroyuki Iwamoto, Kogiku Shiba, Kazuo Inaba, Hitoshi Sakakibara 2154-Pos Board B424 CORRELATION BETWEEN PHOTOSENSITIZER-MEDIATED OXIDATIVE STRESS AND AGING STRESS FOR RED BLOOD CELL MEMBRANE ME- CHANICAL PROPERTY. Koji Kinoshita , Gustavo Scanavachi, Tayana M. Tsubone, Vita Solovyeva, Jonathan Brewer, Rosangela Itri 2155-Pos Board B425 MEASUREMENT AND MODELING OF MICROTUBULE TIP DYNAMICS.  Joseph M. Cleary 2156-Pos Board B426 TARGETING TUMOR CELLS BY ACTIN-REGULATED NUCLEAR ENVELOPE RUPTURE. Marc-Antoine Rodrigue , Claire Dziengelewski, Kévin Jacquet, Alexia Caillier, Jonathan Bergeman, François Bordeleau, Marc-Étienne Huot, Josée N. Lavoie 2157-Pos Board B427 CONTRACTILE RING CONSTRICTION AND CELL WALL GROWTH ARE REGULATED BY MECHANICAL FEEDBACK AND DESTABILIZED BY MUTA- TIONS IN FISSION YEAST. Sathish Thiyagarajan , Zachary A. McDargh, Shuyuan Wang, Ben O’Shaughnessy 2158-Pos Board B428 REPLACEMENT OF MYOSIN MOLECULES WITHIN CARDIAC THICK FILA- MENTS IN INTACT MOUSE HEARTS. Michael J. Previs , Jody L. Martin, Jeffrey L. Spees, Thomas S. O’Leary 2159-Pos Board B429 MICRORHEOLOGY OF ACTIN-VIMENTIN-MICROTUBULE COMPOSITE CYTOSKELETAL NETWORKS. Yinan Shen

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