Biophysical Society 2020 Annual Meeting

2564-Pos Board B110 STRUCTURE AND DRUG RESISTANCE OF THE PLASMODIUM FALCIPARUM TRANSPORTER PFCRT.  Jonathan Kim , Yong Zi Tan, Kathryn J. Wicht, Satchal K. Erramilli, Satish K. Dhingra, John Okombo, Jeremie P. Vendome, Laura M. Hagenah, Sabrina I. Giacometti, Clinton S. Potter, Bridget Carragher, Anthony A. Kossiakoff, Matthias Quick, David A. Fidock, Filippo Mancia 2565-Pos Board B111 EXPRESSION AND PURIFICATION OF A MAMMALIAN TRPV4 FOR FUNC- TIONAL AND STRUCTURAL ANALYSES. Efren Garcia-Maldonado , Francisco J. Sierra Valdez, Valeria Vasquez, Julio F. Cordero-Morales 2566-Pos Board B112 THE OPEN AND CLOSED STRUCTURE OF A BARIUM-BLOCKED POTASSIUM CHANNEL. Ahmed Rohaim , LiDong Gong, Jing Li, Lydia Blachowicz, Benoit Roux 2567-Pos Board B113 MOLECULAR DYNAMICS SIMULATIONS OF THE A 2A G-PROTEIN COUPLED RECEPTOR. Liam I. Haas-Neill , Sarah Rauscher 2568-Pos Board B114 MAMMALIAN STEAROYL-COA DESATURASE FORMS A STABLE TERNARY COMPLEX WITH CYTOCHROME B 5 AND CYTOCHROME B 5 REDUCTASE.  Ji- emin Shen , Gang Wu, Ah-Lim Tsai, Ming Zhou 2569-Pos Board B115 MODELLING OF ION AND WATER PERMEATION IN THE OUTWARD FACING CONFORMATION OF HUMAN ANION EXCHANGER 1. Hristina R. Zhekova , Jiansen Jiang, Hong Zhou, Alexander Pushkin, Sergei Y. Noskov, Ira Kurtz 2570-Pos Board B116 HIGH-RESOLUTION ARCHITECTURE OF BACTERIAL OUTER MEMBRANE PORIN LAMB. Tae Gyun Kim , Jaekyung Hyun, Euikyung Yu, Matthias Wolf 2571-Pos Board B117 INVESTIGATING THE STRUCTURAL TOPOLOGY OF PINHOLIN INCORPORAT- ED INTO ALIGNED LIPID BILAYERS. Rasal H. Khan , Tanbir Ahammad, Robert M. McCarrick, Gary A. Lorigan 2572-Pos Board B118 EFFECT OF CHOLESTEROL ON THE STRUCTURAL DYNAMICS OF METABO- TROPIC GLUTAMATE RECEPTOR (MGLUR 1 ): A MOLECULAR DYNAMICS STUDY. Ugochi Isu , Seyed Hamid Tabari, Vivek Govind Kumar, Mahmoud Moradi 2573-Pos Board B119 STRUCTURAL INSIGHT OF THE COMPLEX OF TREM2 AND DAP12 IN MEM- BRANE BILAYER. Younghee Park , Charles R. Sanders, Jens Meiler 2574-Pos Board B120 BIOCHEMICAL AND STRUCTURAL CHARACTERIZATION OF ENZYMES RESPONSIBLE OF POLYMYXIN RESISTANCE IN GRAM-NEGATIVE BACTE- RIA. Daniel Munoz , Marcelo C. Sousa 2575-Pos Board B121 ENTROPY PRODUCTION IN PROTEIN AGGREGATION.  Salvatore Capotosto , Bailey Smoot, Yelena Nemchen, Randal Hallford, Preet Sharma 2576-Pos Board B122 PODOCIN REGULATES THE NEPHRIN-NEPHRIN DISTANCE IN THE GLOMER- ULAR PORE. Gusztav Schay , Violetta Antal, Máté Kétszeri, Katalin Csókay, Miklós S. Kellermayer, Dóra Karancsiné Menyhárd, Kálmán Tory 2577-Pos Board B123 STRUCTURAL INSIGHT INTO VACUOLAR ABC TRANSPORTER MLT1 OF CANDIDA ALBICANS . Nitesh K. Khandelwal , Tarjani M. Thaker, Thomas M. Tomasiak

2578-Pos Board B124 STRUCTURE AND CATALYTIC MECHANISM OF HUMAN DIACYLGLYCEROL O-ACYLTRANSFERASE 1. Lie Wang , Hongwu Qian, Yin Nian, Yimo Han, Zhenning Ren, Hanzhi Zhang, Liya Hu, B V Venkatar Prasad, Nieng Yan, Ming Zhou Membrane Protein Dynamics III (Boards B125 - B144) 2579-Pos Board B125 MODULATION OF 5-HT1A G PROTEIN COUPLED RECEPTOR MOVEMENT AND INTERNALIZATION. Austin M. Baggetta , Xavier Michalet, Leigh D. Plant 2580-Pos Board B126 SIMULATIONS OF ACTIVE TRANSPORT ACROSS THE BLOOD-BRAIN BAR- RIER. Christian Jorgensen , Martin Ulmschneider, Peter C. Searson 2581-Pos Board B127 EVIDENCE FOR DIRECT MEMBRANE INTERACTION AND CHOLESTEROL SENSING OF A-LOOP IN ABC TRANSPORTER ABCG2. Ali Rasouli , Karan Kapoor, Po-Chao Wen, Emad Tajkhorshid 2582-Pos Board B128 G-PROTEIN-COUPLED RECEPTORS ARE SOLVENT-SWOLLEN IN THE FUNCTIONALLY ACTIVE STATE. Steven D. Fried , Anna R. Eitel, Nipuna Weerasinghe, Gabrielle I. Fitzwater, Johnathan D. Somers, Udeep Chawla, Michael C. Pitman, Blake Mertz, Andrey V. Struts, Suchithranga M. Perera, Michael F. Brown 2583-Pos Board B129 UNRAVELING THE MECHANISM OF THE MFS MULTIDRUG TRANS- PORTER USING STEERED MOLECULAR DYNAMICS. Ruhar Singh , Atanu Banerjee, Amresh Prakash, AndrewM. Lynn 2584-Pos Board B130 ELECTROSTATIC MEMBRANE INTERACTION OF SYNAPTOTAGMIN-LIKE PROTEIN 4: SIMULATIONS OF MUTANT C2A DOMAINS. Mikias Negussie , Sherleen Tran, Nara L. Chon, Julianna Oviedo, Aml Alnaas, Jefferson Knight, Hai Lin 2585-Pos Board B131 USING MOLECULAR DYNAMICS SIMULATIONS TO PREDICT SPECTRAL PEAK SENSITIVITIES OF THE BACTERIORHODOPSIN PHOTOCYCLE.  Kyle Billings , Blake Mertz 2586-Pos Board B132 MOLECULAR INSIGHTS INTO THE ACTIVITY AND STRUCTURAL IMPACTS OF ENZYMES ACROSS THE DYNAMIC PH ENVIRONMENT IN SEA SPRAY AEROSOLS. Nicholas A. Wauer , Abigail C. Dommer, Rommie E. Amaro 2587-Pos Board B133 CONFORMATIONAL DYNAMICS OF MULTIDRUG RESISTANCE PROTEIN 1 DURING ACTIVE TRANSPORT. Ling Wang , Zachary L. Johnson, Michael R. Wasserman, Jesper Levring, Jue Chen, Shixin Liu 2588-Pos Board B134 DYNAMICS OF THE HUMAN Y1-RECEPTOR IN THE INACTIVE AND APO STATES INVESTIGATED BY SOLID-STATE NUCLEAR MAGNETIC RESO- NANCE SPECTROSCOPY AND MOLECULAR DYNAMICS SIMULATIONS.  Alexander Vogel , Hossein Batebi, Johanna K. Tiemann, Marcel Gauglitz, Mathias Bosse, Daniel Huster, Peter W. Hildebrand 2589-Pos Board B135 PROBING THE DYNAMIC ASPECTS OF ACRB FUNCTION THROUGH DISUL- FIDE BOND FORMATION. Prasangi Rajapaksha , Yinan Wei

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