Biophysical Society 2020 Annual Meeting

327-Pos Board B158 SINGLE-MOLECULE MEASUREMENT OF SHORT DSDNA AND A 6 -TRACT STIFFNESS AND BENDING USING DNA NUNCHUCKS. Xinyue Cai , Deborah K. Fygenson 328-Pos Board B159 A SIMPLE THERMODYNAMIC MODEL FOR DNA-STRAND DISPLACEMENT REACTIONS IN PRESENCE OF BASE-PAIR MISMATCHES. Patrick Irmisch , Marius Rutkauskas, Ralf Seidel 329-Pos Board B160 Travel Awardee INHOMOGENEOUS FORCES IN SEMIFLEXIBLE BIOPOLYMERS.  Ananya Mondal , Gregory Morrison RNA Structure and Dynamics (Boards B161 - B179) 330-Pos Board B161 INFLUENCE OF SEQUENCE VARIATION ON RNA 3WJ HELICAL ORIENTA- TION STUDIED BY HIGH-PRECISION FRET. Olga Doroshenko , Hayk Vardan- yan, Aiswaria Prakash, Sascha Froebel, Stanislav Kalinin, Simon Sindbert, Oleg Opanasyuk, Christian A. Hanke, Sabine Mueller, Holger Gohlke, Claus Board B162 SINGLE-MOLECULE THREE-COLOR FRET REVEALS MULTI-STATE CONFOR- MATIONAL DYNAMICS OF RNA FOUR-WAY JUNCTIONS. Anders Barth , Christian A. Hanke, Oleg Opanasyuk, Hayk Vardanyan, Simon Sindbert, Stanislav Kalinin, Claus A. Seidel 332-Pos Board B163 RNA STRUCTURAL ENSEMBLES ACT AS A GATE KEEPER OF 3’ ALTERNA- TIVE SPLICING. Robb S. Welty , Nils G. Walter 333-Pos Board B164 STRUCTURAL DETERMINANTS OF MRNA TRANSPORT SPECIFICITY IN OLIGODENDROCYTES. Ved V. Topkar 334-Pos Board B165 BIOPHYSICAL CHARACTERIZATION OF G-QUADRUPLEX STRUCTURE IN LONG NONCODING RNA NEAT1. Emily M. Benner , Mihaela-Rita Mihai- lescu 335-Pos Board B166 ELUCIDATING THE ROLE OF THE G-QUADRUPLEX STRUCTURE IN THE MATURATION OF A PRE-MICRORNA VARIANT IN ALZHEIMER’S DIS- EASE.  Joshua A. Imperatore , McKenna L. Then, Keefe B. McDougal, Mihaela-Rita Mihailescu 336-Pos Board B167 COMPETITION BETWEEN LIGAND BINDING AND TRANSCRIPTION RATE MODULATES RIBOSWITCH-MEDIATED REGULATION OF TRANSCRIP- TION. Adrien Chauvier, Pujan Ajmera , Nils G. Walter 337-Pos Board B168 SOLVATION EFFECTS IN RNA SYSTEMS. Clark Templeton 338-Pos Board B169 CAPTURING THE INFLUENCE OF SOLVENT AND NEIGHBORING RESIDUES IN A FIXED-CHARGE FORCE FIELD FOR RNA. Chapin E. Cavender , Louis G. Smith, Alan Grossfield, David H. Mathews 339-Pos Board B170 QUANTITATIVE ANALYSIS OF SALT-INDUCED RNA DUPLEX VARIATIONS BY WIDE-ANGLE X-RAY SCATTERING (WAXS). Yen-Lin Chen , Lois Pollack 340-Pos Board B171 EXPLORING THE ION-MEDIATED RNA INTERACTIONS OF A HELIX-JUNC- TION-HELIX RNA MODEL THROUGH WELL-TEMPERED METADYNAMICS SIMULATIONS. Diego E. Kleiman , Nawavi Naleem, Serdal Kirmizialtin A. Seidel 331-Pos

341-Pos

Board B172

Travel Awardee

ROLE OF METAL IONS IN RNA TETRALOOP HAIRPIN MOTIF FORMA- TION. Antarip Halder , Sunil Kumar, Govardhan Reddy Patluri 342-Pos Board B173 PROBING MG +2 -MEDIATED RNA-RNA INTERACTIONS IN THE PRESENCE OF METABOLITES. Derrick R. Lin , Suzette A. Pabit, Lois Pollack 343-Pos Board B174 EFFECT OF MG 2+ IONS ON TPP RIBOSWITCH APTAMER FOLDING.  Sunil Kumar , Govardhan Reddy 344-Pos Board B175 EFFECT OF PRESSURE ON RNA G-QUADRUPLEX STRUCTURES.  Balasubramanian Harish , Roland Winter, Catherine A. Royer 345-Pos Board B176 UNDERSTANDING THE SHAPE REAGENT BINDING FROM RNA DYNAM- ICS. Fengfei Wang , Xiaojun Xu 346-Pos Board B177 QUANTIFYING STRUCTURAL DIVERSITY OF CNG TRINUCLEOTIDE REPEATS USING DIAGRAMMATIC ALGORITHMS. Ethan Phan , Chi H. Mak 347-Pos Board B178 DISCOVERING DESIGN PRINCIPLES TO RE-ENGINEER FUNCTIONAL RNA ELEMENTS. Alex Plumridge , Lois Pollack 348-Pos Board B179 FUNCTIONAL AND TEMPLATING ABILITY OF FLUORESCENT RNA AP- TAMERS IN POSSIBLE PREBIOTIC CONDITIONS. Ranajay Saha , Samuel Verbanic, Irene A. Chen Protein-Nucleic Acid Interactions I (Boards B180 - B212) 349-Pos Board B180 EXPLORATION OF CONFIGURATIONAL AND TOPOLOGICAL PROPERTIES OF MINICHROMOSOMES USING ELASTIC ENERGY OPTIMIZATIONS AT THE DNA BASE-PAIR LEVEL. Robert T. Young , Wilma K. Olson 350-Pos Board B181 E. COLI SINGLE STRANDED BINDING PROTEIN (SSB) SELF-REGULATES WRAPPING OF SSDNA THROUGH COMPETITIVE BINDING. M. Nabuan Naufer, Michael Morse, Gudfridur B. Moller , James McIsaac, Ioulia Rouzina, Penny J. Beuning, Mark C. Williams 351-Pos Board B182 REGULATION OF NEAREST-NEIGHBOR COOPERATIVE BINDING OF E.COLI SSB PROTEIN TO SSDNA BY ITS INTRINSICALLY DISORDERED REGIONS.  Alexander G. Kozlov , Min Kyung Shinn, Timothy M. Lohman 352-Pos Board B183 SINGLE MOLECULE BINDING DYNAMICS OF LINE-1 ORF1P TO SSD- NA. Benjamin A. Cashen , M. Nabuan Naufer, Charlie E. Jones, Anthony V. Furano, Mark C. Williams 353-Pos Board B184 SLIDING, FAST AND SLOW: DISTINCT DIFFUSION MECHANISMS OF EU- KARYOTIC AND PROKARYOTIC DNA CLAMPS.  Jejoong Yoo , Sang Hak Lee 354-Pos Board B185 SINGLE-MOLECULE IMAGING OF PAF15-PCNA USING DNA SKY- BRIDGE. Daehyung Kim , Alfredo D. biasio, Amaia Gonzalez-Magaña, Gayun Bu, Fahad Rashid, Samir Hamdan, Francisco Blanco, Jong-Bong Lee Lee

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