Biophysical Society 63rd Annual Meeting | Program Guide

Muscle Regulation (Boards B268 - B276) 1905-Pos Board B268 CYTOTOXICITY OF TRUNCATED SLOW SKELETAL MUSCLE TROPONIN T IN TNNT1 MYOPATHIES. Hanzhong Feng , J.-P. Jin 1906-Pos Board B269 LOSS OF THE SLOW SKELETAL MUSCLE ISOFORM OF TROPONIN T IM- PAIRS MOTOR COORDINATION IN MICE. Kentaro Oki , Han-Zhong Feng, J.-P. Jin 1907-Pos Board B270 MYOSIN BINDING PROTEIN-C SLOW IN HEALTH AND DISEASE.  Janelle Geist , Janis Stavusis, Baiba Lace, Nathan T. Wright, Christopher W. Ward, Carsten Bonnemann, Aikaterini Kontrogianni-Konstantopou 1908-Pos Board B271 EXPRESSION OF MYOSIN STORAGE MYOPATHY MUTATIONS IN DRO- SOPHILA DISRUPTS SKELETAL AND CARDIAC MUSCLE STRUCTURE AND FUNCTION. Meera C. Viswanathan 1909-Pos Board B272 FLUORESCENTLY LABELLED MYOSIN REGULATORY LIGHT CHAINS AS BIO- SENSORS FOR THICK FILAMENT ACTIVATION IN HEART MUSCLE. Priyanka Parijat , Malcolm Irving, Thomas Kampourakis 1910-Pos Board B273 STRAIN-DEPENDENCE OF THE ACTIN-MYOSIN WORKING STEP.  Josh E. Baker , Travis J. Stewart, Christine R. Cremo 1911-Pos Board B274 TRAVEL AWARDEE EFFECTS OF ACTIN-BINDING COMPOUNDS ON THE ATPASE ACTIVITY OF MYOSIN FROM SKELETAL AND CARDIAC MUSCLE. Ananya Tripathi , Lien A. Phung, Piyali Guhathakurta, David D. Thomas 1912-Pos Board B275 TRAVEL AWARDEE THE ROLE OF UBIQUITIN-PROTEASOME SYSTEM (UPS)-ASSOCIATED GENES IN THE PRESERVATION OF CARDIAC AND MUSCLE FUNCTION IN DROSOPHILA MELANOGASTER. Maria L. Khan 1913-Pos Board B276 MODELING THE CYTOTOXIC SWELLING OF DYSTROPHIC MUSCLE FI- BERS. Catherine E. Morris , Bela Joos Voltage-gated Na Channels (Boards B277 - B297) 1914-Pos Board B277 FGF12A COUNTERACTS LONG QT SYNDROME-LINKED INACTIVATION DEFICIENCY. Paweorn Angsutararux 1915-Pos Board B278 AN ATTEMPTED MOLECULAR RESCUE OF AN ARRHYTHMOGENIC CAR- DIAC DISEASE MUTATION. Sara Nathan , Sophie Shoemaker, Federica Fari- nelli, Jesse Yoder, L.Mario Amzel, Gordon F. Tomaselli, Sandra B. Gabelli 1916-Pos Board B279 CONSTANT PH STUDY OF A SODIUM CHANNEL. Ana Damjanovic , Ada Y. Chen, Robert L. Rosenberg, Daniel Roe, Bernard R. Brooks 1917-Pos Board B280 PROTX-II INHIBITS NAV1.7 THROUGH AN ELECTROSTATIC GATING MODU- LATION MECHANISM. Tianbo Li 1918-Pos Board B281 DIFFERENCES BETWEEN TONIC AND USE-DEPENDENT BINDING SITES IN VOLTAGE-GATED SODIUM CHANNELS. Amanda Buyan, Ben Corry

1919-Pos Board B282 SODIUM CHANNELS IMPLEMENT A MOLECULAR LEAKY INTEGRATOR TO SENSE SPIKING FREQUENCY AND REGULATE NEURONAL FIRING. Marco A. Navarro , Jenna Lin, Autoosa Salari, Mirela MIlescu, Lorin S. Milescu 1920-Pos Board B283 MULTISCALE MOLECULAR DYNAMICS TO EXPLORE VOLTAGE-GATED SO- DIUM CHANNEL OLIGOMERISATION. William Glass , Philip C. Biggin 1921-Pos Board B284 ENUMERATING VIABLE N-STATE MARKOV MODELS OF SODIUM CHANNEL DYNAMICS. Kathryn Mangold , Jonathan Silva 1922-Pos Board B285 BIOPHYSICAL AND PHARMACOLOGICAL PROFILING OF MULTIPLE VOLTAGE-GATED SODIUM CHANNEL SUBTYPES ON QPATCH II. Daniel R. Sauter , Rasmus B. Jacobsen, Goeran Mattsson 1923-Pos Board B286 IN SEARCH OF A MOLECULAR MECHANISM FOR SLOW INACTIVATION IN VOLTAGE-GATED NA CHANNELS USING THE SCAM TECHNIQUE IN D2-S6 OF HNAV1.4.  John P. O’Reilly , Kevin Bokum, Jonathan Beard, Penny Shockett 1924-Pos Board B287 INTERACTION OF NA V 1.2 IQ MOTIF WITH DISEASE-CAUSING MUTANTS OF CALMODULIN. Ryan W. Mahling , Adina M. Kilpatrick, Holly M. Isbell, Madeline A. Shea 1925-Pos Board B288 PRODUCTION AND APPLICATIONS OF NANOBODIES AGAINST VOLTAGE- GATED SODIUM CHANNEL, NAV1.4. Lakshmi Srinivasan 1926-Pos Board B289 USING SCAM TO INVESTIGATE RECONFIGURATION OF MOLECULAR DETERMINANTS IN D1-S6 DURING SLOW INACTIVATION OF HNAV1.4.  Jon M. Beard , Penny Shockett, John P. O’Reilly 1927-Pos Board B290 THE INSECTICIDE FENVALERATE BINDS TO NAVMS SODIUM CHANNELS, MAKING THEM A SUITABLE TEMPLATE FOR MODELLING STRUCTURES OF HOUSEFLY-INSECTICIDE COMPLEXES. Altin Sula , Edina Molnar, Bonnie A. Wallace 1928-Pos Board B291 NA CHANNEL ACTIVATION AND INACTIVATION: ROLE OF DOMAIN 4. Clay M. Armstrong , Steve Hollingworth 1929-Pos Board B292 EXTRACELLULAR ACIDOSIS EXHIBITS DOMAIN-SPECIFIC EFFECTS ON NAV1.5. Emily M. Wagner , Brittany D. Brumback, Taylor L. Voelker, Wandi Zhu, Jonathan R. Silva 1930-Pos Board B293 BIOPHYSICAL AND MOLECULAR CHARACTERIZATION OF CALCIUM PERMEABLE HONEYBEE DSC1 (AMCA V 4) CHANNEL EXPRESSED IN MAM- MALIAN CELLS. Olivier Thériault, Matthieu Rousset, Collet Claude, Thierry Cens, Pierre Charnet, Mohamed Chahine 1931-Pos Board B294 DOMAIN I COUNTERCHARGES LIMIT SLOW INACTIVATION IN HNAV1.4 SODIUM CHANNELS.  James R. Groome , Andromeda Wheeler, Ryann Camp 1932-Pos Board B295 TRAVEL AWARDEE CARDIAC SODIUM CURRENT IS SEVERELY IMPAIRED IN INDUCED PLU- RIPOTENT STEM CELL-DERIVED CARDIOMYOCYTES FROM BRUGADA SYN- DROME PATIENTS. Rebecca Martinez-Moreno , Elisabet Selga, Georgia Sarquella-Brugada, Ramon Brugada, Guillermo Perez, Fabiana Scornik

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