Biophysical Society 63rd Annual Meeting | Program Guide

Platform Membrane Physical Chemistry I 8:15 am - 10:15 am, Room 314/315

112-Plat 9:00 am ELUCIDATING COMPLIMENTARY BASE SPECIFICITY OF THYMINE DNA GLYCOSYLASE VIA POTENTIAL OF MEAN FORCE MOLECULAR DYNAMICS SIMULATIONS.  Ozge Yoluk , Alexander C. Drohat, Alexander D. MacKerell 113-Plat 9:15 am RNAP AS A MOVING BARRIER TO LOOP EXTRUSION.  Aafke A. van den Berg , Gordana Wutz, Roman R. Stocsits, Hugo Brandao, Georg Busslinger, Jan-Michael Peters, Leonid Mirny 114-Plat 9:30 am SINGLE MOLECULE IMAGING OF CTCF AND COHESIN. DISSECTING THE DYNAMIC INTERPLAY BETWEEN CHROMATIN LOOP REGULATORS.  Laura Caccianini , Elphege P. Nora, Johannes Nuebler, Agnes LesSaux, Edith Heard, Leonid Mirny, Benoit Bruneau, Maxime Dahan 115-Plat 9:45 am THE THREE-DIMENSIONAL ARCHITECTURE OF THE HUMAN GENOME: IT’S NUCLEAR PHYSICS! Michele Di Pierro 116-Plat 10:00 am MEASURING THE PHYSICAL PROPERTIES OF DNA ON A GENOMIC SCALE.  Aakash Basu , Tunc Kayikcioglu, Thuy Ngo, Quicen Zhang, Basilio Cieza Huaman, Miroslav Hejna, Tomas Rube, Jun Song, Taekjip Ha Career Development Center Workshop Networking for Nerds: How to Create Your Dream Career 9:00 am - 10:00 am, Exhibit Hall A Wanna land your dream job? Get ready to network! Most jobs and other game-changing career opportunities are not advertised, and even if they are, there is usually a short-list of candidates already in mind. So how do you find out about and access the 90% of jobs and other opportunities that are “hidden”? In this workshop, we will focus on proven networking strategies and tactics to identify new opportunities, locate decision-mak- ers within organizations, solidify your reputation and brand in the minds of those who hire, and gain access to hidden jobs and game-changing opportunities. Discover how networking and self-promotion can enable you to land or even create your dream job from scratch! Mizar Imaging is proud to introduce the Tilt, the first high-resolution light sheet imaging system that is a simple add-on to most inverted micro- scopes. When installed on your microscope, the Tilt does not interfere with any existing modalities so you can easily add the Tilt to an inverted microscope, including a TIRF or Spinning Disc confocal microscope sys- tem, to add the ability to do long term live cell imaging with the lowest possible photobleaching and phototoxicity. The Tilt is well-suited to image both larger organisms, such as C. elegans, Drosophila, Danio rerio and other similar model organisms as well as imaging high-resolution intracellular dynamics inside single cells. This re- markable diversity is realized because the Tilt can work with any objective on your microscope – from 20x through 150x. There is no limit to what you can do with the Tilt. The key benefit of light sheet imaging is significantly reducing the pho- tobleaching and phototoxicity of your sample. The Tilt is no exception. CID Committee Meeting 8:30 am - 10:30 am, Room 333 Exhibitor Presentation Mizar Imaging 9:30 am - 11:00 am, Room 303 TILT – HIGH-RESOLUTION LIGHT SHEET IMAGING

S U N D A Y

Co-Chairs Shelli Frey, Gettysburg College Wade Zeno, University of Texas at Austin 101-Plat 8:15 am

TUNING LENGTH SCALES OF A MODULATED PHASE IN MODEL AND CELL- DERIVED MEMBRANES.  Caitlin E. Cornell , Allison D. Skinkle, Shushan He, Ilya Levental, Kandice R. Levental, Sarah L. Keller 102-Plat 8:30 am TWISTING OF A MECHANOSENSITIVE MOLECULAR PROBE DETECTS LIPID ORDER IN MEMBRANES.  Giuseppe Licari , Emad Tajkhorshid 103-Plat 8:45 am HOMEOVISCOUS ADAPTATION IN MAMMALIAN CELL MEMBRANES IN RESPONSE TO DIETARY LIPID PERTURBATIONS.  Kandice R. Levental , Ilya 9:00 am LIQUID-CRYSTAL PHASE TRANSITIONS IN CELLULAR LIPID DROPLETS.  Julia Mahamid 105-Plat 9:15 am TRAVEL AWARDEE CHARACTERISTIC CONFORMATIONS OF PSEUDOMONAS QUINOLONE SIGNAL INTERACTING WITH BACTERIAL OUTER MEMBRANE.  Ao Li , Jef- frey W. Schertzer, Xin Yong 106-Plat 9:30 am MEASURING THE INTERACTION OF POLYGLUTAMINE PEPTIDES WITH LIPID MEMBRANES. Warren A. Campbell, Maxmore Chaibva, Xiang Gao, Ziliang Zhao, Justin Legleiter, Shelli L. Frey 107-Plat 9:45 am A LINK BETWEEN PEPTIDE LIPIDATION AND MEMBRANE CURVATURE MODULUS.  John M. Sanderson , Hannah M. Britt, Jackie A. Mosely 108-Plat 10:00 am INTRINSICALLY DISORDERED PROTEINS SENSE MEMBRANE CURVATURE.  Wade F. Zeno , Upayan Baul, Wilton T. Snead, Andre C.M. DeGroot, Liping Wang, Eileen M. Lafer, Dave Thirumalai, Jeanne C. Stachowiak Platform DNA Structure, Dynamics, and Function 8:15 am - 10:15 am, Room 316/317 Co-Chairs Jieqiong Lou, University of Melbourne, Australia Michele DiPierro, Rice University 109-Plat 8:15 am MSH4-MSH5 INDUCED DNA CONFORMATIONAL CHANGES PROVIDE INSIGHTS INTO ITS ROLE IN MEIOTIC RECOMBINATION.  Sudipta Lahiri , Bharat Lakhani, Yan Li, Manju M. Hingorani, David L. Beveridge, Ishita Mukerji 110-Plat 8:30 am FLUORESCENCE FLUCTUATION SPECTROSCOPY REVEALS DOUBLE STRAND BREAK RECRUITMENT OF 53BP1 DIMERS AND ASSEMBLY INTO HIGHER- ORDER OLIGOMERS AT THE DNA REPAIR LOCUS.  Jieqiong Lou , Jee Khor, David Priest, Elizabeth Hinde 111-Plat 8:45 am REPLICATION ORIGINS EXPOSED ON THE SURFACE OF A REPLICATION DOMAIN BY TRANSCRIPTION ELONGATION ARE PREFERENTIALLY FIRED FOR DNA REPLICATION.  Yongzheng Li Levental 104-Plat

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