Biophysical Society 63rd Annual Meeting | Program Guide

Understanding the Congressional Budget Process How Science is Funded 1:00 pm - 2:30 pm, Room 318/319/320 In 2018, Congress approved a major budget deal that raised the discre- tionary spending caps for the first time since sequestration. However, when this budget deal expires in 2019, Congress will face a potential funding cliff. How will the National Institutes of Health (NIH), the National Science Foundation (NSF), and other science-related agencies do under the next budget deal? Will Congress even pass a new budget deal? Which agencies fund scientific research and how does Congress negotiate their funding levels? Join our panel of government and industry insiders as we explore how the Congressional budget is developed, historical trends in science funding, and what the future may hold! Panelist Tiffany Kaszuba, Deputy Director, Coalition for Health Funding Biophysics 101 Gene Editing 1:30 pm - 3:00 pm, Room 307/308 Gene editing refers to the modification of genetic material in living organisms by introducing insertions, deletions or base-pair changes. These modifications have been greatly facilitated by the discovery of the CRISPR/Cas9 system in bacteria and subsequent adaptations for higher organisms. The speakers in this session will focus on new methods be- ing developed for gene editing using CRISPR/Cas9 and related CRISPR systems, including RNA editing, tissue-specific gene editing, therapeutic strategies, and applications to plant breeding and crop development. Moderator Sharyn Endow, Duke University Presenters Patrick Hsu, Salk Institute Greg Gocal, Cibus Exhibitor Presentation Bruker Corporation 1:30 pm - 3:00 pm, Room 303 INVESTIGATING DYNAMIC BIOLOGICAL PROCESSES WITH HIGH-SPEED, HIGH-RESOLUTION CORRELATIVE AFM-LIGHT MICROSCOPY The ability of atomic force microscopy (AFM) to obtain three-dimen- sional topography images of biological molecules and complexes with nanometer resolution and under near-physiological conditions remains unmatched by other imaging techniques. However, the typically longer image acquisition times required to obtain a single high-resolution im- age (~minutes) has limited the advancement of AFM for investigating dynamic biological processes. While recent years have shown significant progress in the development of high-speed AFM (HS-AFM), the ability to scan faster has typically been achieved at the cost of decreased scanner range and restricted sample size. As such, these HS-AFM systems have mainly been focused on studying single molecule dynamics and have been very limited in their ability to conduct live cell imaging. The novel NanoWizard® ULTRA Speed A AFM not only enables high- speed studies of time-resolved dynamics associated with cellular processes, it’s latest scanner technologies and compact design also allow full integration of AFM into advanced commercially available light microscopy techniques. Thus, fast AFM imaging of several frames per second can be seamlessly combined with methods such as epifluorescence, confocal, TIRF, STED microscopy, and many more.

Please join us for this informative seminar where we will present how the latest advances in the ULTRA Speed A AFM are being applied to study a wide-range of biological samples, from individual biomolecules to mam- malian cells and tissues. We will also describe how this unique system is enabling new research opportunities with high-speed, highresolution correlative AFM-light microscopy. Speaker Andrea Slade, BioAFM Product Manager, JPK BioAFM Center, Bruker Nano Surfaces Snack Break 1:45 pm - 3:00 pm, Exhibit Hall Poster Presentations and Late Posters 1:45 pm - 3:45 pm, Exhibit Hall Virtual Biophysics Virtual and Augmented Reality Meets Biophysics 2:15 pm - 3:45 pm, Room 324/325/326 As virtual reality has become cheaper and more accessible, the research and educational applications of this technology have grown. Virtual, aug- mented, and mixed reality (VR, AR, and MR) technologies offer immersive experiences by exposing human senses to computer-generated sounds, images, and haptic stimulations. This session will showcase to research- ers, educators, and students how these technologies are being applied in biophysics research and education and offer participants a chance to test out these new tools and experience the power and prospects of VR and AR in the classroom and the research lab. Career Development Center Workshop The Strategic Postdoc: How to Find & Leverage Many PhDs just kind of fall in to a postdoc, rather than thinking about it from a strategic perspective. Your postdoc is never an end in itself; rather it’s a means to another end whether that goal is a faculty position at a re- search university, a small college, or perhaps a job in industry or govern- ment. Learn how to find postdoc opportunities that will best prepare you for that next step, and how to use your postdoc experience to facilitate the transition to your next position. Speed Networking 2:30 pm - 4:00 pm, Mezzanine Level Career development and networking are important in science, but can be a big time commitment. In this session we offer the chance to speed network, an exciting way to connect with a large number of biophysicists (including Biophysical Society committee members) in a short amount of time. Mid-career and more experienced scientists could learn how to get more involved in the Society or network for open positions in their labs. Early career scientists could discuss career goals and challenges, get advice on tenure or grant writing, or find out how to gain recognition for their work. Graduate students and postdocs could make contacts to find their next position. After introductions, each person will have short 3-5 minute meetings with consecutive new contacts. During this time you can exchange information and ask questions. When time is up, you select the next person to talk to. By the end of the event, each participant will have had meaningful interactions with over half a dozen colleagues and the opportunity to meet many more. It’s that simple! Space is limited for this event and pre-registration was recommended to ensure a spot. your Postdoc Experience 2:30 pm - 3:30 pm, Exhibit Hall A

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