Biophysical Society 63rd Annual Meeting | Program Guide

857-Plat 5:45 pm INHIBITION OF HCN CHANNELS BY BETA-BLOCKER CARVEDILOL.  Pingzheng Zhou , Ying Cao Platform Optical Microscopy and Superresolution Imaging II 4:00 pm - 6:00 pm, Ballroom IV Co-Chairs Janet Sheung, Vassar College Paul Wiggins, University of Washington 858-Plat 4:00 pm SINGLE PARTICLE TRAJECTORIES REVEAL ACTIVE ENDOPLASMIC RETICULUM LUMINAL FLOW.  Pierre Parutto , Joseph E. Chambers, Marcus Fantham, Laurence Young, Stefan Marciniak, Clemens F. Kaminski, David Ron, David Holcman, Edward Avezov 859-Plat 4:15 pm CHROMATIN NANOSCALE ORGANIZATION INVESTIGATED BY FLIM-FRET AND STED SUPERRESOLUTION MICROSCOPY.  Simone Pelicci , Michele Oneto, Melody Di Bona, Isotta Cainero, Paola Barboro, Alberto Diaspro, Luca Lan- zano’ 860-Plat 4:30 pm SINGLE NITROGEN-VACANCY IMAGING IN NANODIAMONDS FOR MULTI- MODAL SENSING. Maabur Sow , Horst Steuer, Barak Gilboa, Laia Gines, Sou- men Mandal, Sanmi Adekanye, Jason M. Smith, Oliver A. Williams, Achillefs N. Kapanidis 861-Plat 4:45 pm ACTIVE FEEDBACK TRACKING OF SINGLE VIRUSES AND FLUOROPHORES IN SOLUTION.  Kevin D. Welsher 862-Plat 5:00 pm SUPER-RESOLUTION MICROSCOPY AS A TOOL FOR COUNTING PROTEINS IN A SUB-CELLULAR ENVIRORMENT.  Francesca Cella Zanacchi , Raffaella Magrassi, Carlo Manzo, Nathan Derr, Alberto Diaspro 863-Plat 5:15 pm MOLECULAR COUNTING WITH DNA ORIGAMI - VERIFICATION AND VALIDA- TION TOWARDS BIOLOGICAL APPLICATIONS.  Daniel F. Nino , Daniel Djarkar- sana, Anton Zilman, Joshua Milstein 864-Plat 5:30 pm STRUCTURAL CONTRIBUTIONS TO HYDRODYNAMIC SIZE OF QUANTUM DOTS FOR IN-VIVO SINGLE MOLECULE TRACKING.  Janet Y. Sheung , Pinghua Ge, Sung Jun Lim, Sang Hak Lee, Andrew Smith, Paul R. Selvin 865-Plat 5:45 pm THE OBSERVATION PROTEIN POSITION AND ORIENTATION DYNAMICS USING AN UNBLEACHABLE PROBE.  Paul A. Wiggins Platform Membrane Receptors and Signal Transduction 4:00 pm - 6:00 pm, Room 307/308 Co-Chairs Jinan Wang, University of Kansas Michael Brown, University of Arizona 866-Plat 4:00 pm ACTIVATION AND CROSS-INTERACTION OF RECEPTOR TYROSINE KINASES STUDIED BY SINGLE-PARTICLE TRACKING. Marie-Lena I. E. Harwardt , Sebas- tian Strauss, Ralf Jungmann, Marina S. Dietz, Mike Heilemann 867-Plat 4:15 pm A THERMODYNAMIC FRAMEWORK FOR UNDERSTANDING RTK INTERAC- TION NETWORKS. Michael D. Paul , Kalina Hristova

TO SITES OF DNA DAMAGE.  Karolin Luger Symposium Synthetic Biology 4:00 pm - 6:00 pm, Ballroom II Chair Luis Serrano, Centre for Genomic Regulation, Spain No Abstract 4:00 pm SYNTHETIC BIOLOGY APPROACHES TO BIO-ORTHOGONAL CHEMISTRY.  Michelle Chang 848-Symp 4:30 pm SYNTHETIC ELECTROPHYSIOLOGY.  Harry McNamara, Adam Cohen 849-Symp 5:00 pm MECHANISMS, DIVERSITY AND OPTOGENETIC APPLICATIONS OF CHAN- NELRHODOPSINS FROM CRYPTOPHYTE ALGAE.  Elena G. Govorunova , John L. Spudich No Abstract 5:30 pm ENGINEERING OF MYCOPLASMA PNEUMONIAE AS A THERAPEUTIC VEHICLE TO TREAT LUNG DISEASES.  Luis Serrano Platform Ion Channels, Pharmacology and Disease 4:00 pm - 6:00 pm, Ballroom III Co-Chairs Paola Vergani, University College London, United Kingdom Nurunisa Akyuz, Harvard Medical School 850-Plat 4:00 pm TMC1 FORMS THE PORE OF THE MECHANOSENSITIVE TRANSDUCTION CHANNELS IN INNER EAR HAIR CELLS.  Nurunisa Akyuz , David P. Corey 851-Plat 4:15 pm INHIBITION OF TMEM16A BY DOCOSAHEXAENOIC ACID PLAYS A CRU- CIAL ROLE IN BLOOD VESSEL RELAXATION.  Kathryn E. Acheson , Paolo 4:30 pm FENESTRATIONS CONTROL THE RESTING STATE BLOCK OF A VOLT- AGE GATED SODIUM CHANNEL.  Tamer M. Gamal El-Din , Michael J. Lenaeus, Ning Zheng, William A. Catterall 853-Plat 4:45 pm DOES DISRUPTION OF THE E873-R933 SALT BRIDGE IN CFTR AND ALTERATION OF THE MEMBRANE BILAYER AROUND IT PLAY A BIOLOGI- CAL ROLE?  Emily Langron, Valentina Corradi, Peter D. Tieleman, Paola Vergani 854-Plat 5:00 pm GENERATING POTENT AND SELECTIVE INHIBITORS OF KV1.3 ION CHAN- NEL BY FUSING KNOTTINS (VENOM DERIVED MINI PROTEINS) INTO PE- RIPHERAL CDR LOOPS OF ANTIBODIES.  Aneesh Karatt-Vellatt , Damian C. Bell, Sachin B. Surade, Tim Luetkens, Ed W. Masters, Alice M. Luther, Naja Møller M. Sørensen, Neil J. Butt, John McCafferty 855-Plat 5:15 pm IS THE HYDROPHOBIC GASKET A SECONDARY SELECTIVITY FILTER IN THE HUMAN VOLTAGE GATED PROTON CHANNEL HH V 1?  Richard Banh , Kethika Kulleperuma, Vladimir V. Cherny, Deri Morgan, Boris Musset, Sarah Thomas, Susan M.E. Smith, Régis Pomès, Thomas E. DeCoursey 856-Plat 5:30 pm TRAVEL AWARDEE INVESTIGATING FUNCTIONAL CONSEQUENCES OF NOVEL DISEASE- CAUSING MUTATIONS OF CLCN7 GENE.  Eleonora Di Zanni , Alessandra Picollo Tammaro 852-Plat

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