Biophysical Society 63rd Annual Meeting | Program Guide

1244-Pos Board B346 SIMULATING EMERGENT SPATIOTEMPORAL ACTOMYOSIN DYNAMICS TO UNDERSTAND SPATIAL REGULATION OF NON-MUSCLE MYOSIN II. Callie J. Miller , Paul LaFosse, Sreeja Asokan, Jason Haugh, James E. Bear, Timothy C. Elston 1245-Pos Board B347 THE PHYSICAL BASES OF FORMING A SMOOTH BOUNDARY BETWEEN AN EXPANDING ARP 2/3 ACTIN NETWORK AND A CONTRACTILE ACTOMYO- SIN NETWORK. Medha Sharma , Tony Harris 1246-Pos Board B348 SEPTIN HIERARCHICAL ASSEMBLY REVEALED BY HIGH-SPEED ATOMIC FORCE MICROSCOPY(HS-AFM). Fang Jiao , Kevin Cannon, Amy Gladfelter, Simon Scheuring 1247-Pos Board B349 METAPHASE KINETOCHORE MOVEMENTS ARE REGULATED BY KINESIN-8 MOTORS AND MICROTUBULE DYNAMIC INSTABILITY. Agneza Bosilj , Anna Klemm, Iva Tolić, Nenad Pavin 1248-Pos Board B350 FORCE REGULATION OF CAPPING AND ARP2/3 NUCLEATION OF BRANCHED ACTIN NETWORKS. Tai-De Li , Peter Bieling, Dyche Mullins, Daniel Fletcher 1249-Pos Board B351 SPATIOTEMPORAL ORGANIZATION OF MICROTUBULES IN BRANCHED NETWORKS. Akanksha Thawani , Howard A. Stone, Joshua W. Shaevitz, Sabine Petry 1250-Pos Board B352 TRAVEL AWARDEE PIVOTING OF MICROTUBULES DRIVEN BY MINUS END DIRECTED MOTORS LEADS TO THEIR ALIGNMENT TO FORM AN INTERPOLAR BUNDLE.  Ivana Ban , Marcel Prelogovic, Lora Winters, Iva Tolič, Nenad Pavin 1251-Pos Board B353 NCKIPSD COORDINATES ARP2/3 AND FORMIN NUCLEATION OF ACTIN FILAMENTS IN THE CELL CORTEX. LuYan Cao , Amina Yonis, Malti Vaghela, Priyamvada Chugh, Pierre Bohec, Matt Smith, Genevieve Lavoie, Ewa K. Paluch, Philippe Roux, Antoine G. Jegou, Guillaume Charras, Guillaume Romet-Lemonne 1252-Pos Board B354 DYNAMIC HAND-IN-HAND INTERACTION BETWEEN ACTIN AND SPECTRIN DURING MAMMALIAN CELL MECHANOADAPTATION. Andrea Ghisleni , Camilla Galli, Qinseng Li, Pascale Monzo, Paolo Maiuri, Nils Gauthier 1253-Pos Board B355 COORDINATE ROLE OF VINCULIN AND METAVINCULIN IN ACTIN ORGA- NIZATION. Sharon Campbell , Muzaddid Sarker, Hyunna T. Lee, Laura Kim, Santiago Espinosa de los Reyes, Lin Mei, Andrey Krokhotin, Laura Constantini, Gregory M. Alushin, Nikolay V. Dokholyan, Jack D. Griffith 1254-Pos Board B356 STRUCTURE OF THE TPM3.1 N-TERMINUS: A NEW TARGET FOR ANTI- CANCER TREATMENT. Anita Ghosh , Miro Janco, Till Böcking, Peter W. Gunning, William Lehman, Michael J. Rynkiewicz 1255-Pos Board B357 QUANTIFYING DISSIPATION IN ACTOMYOSIN NETWORKS. Carlos Floyd , Christopher Jarzynski, Garegin A. Papoian Microtubules, Structure, Dynamics, and Associated Proteins (Boards B358 - B380) 1256-Pos Board B358 EXPLORING THE UNFOLDASE MECHANISM OF MICROTUBULE SEVERING BY COARSE-GRAINED SIMULATIONS. Rohith Anand Varikoti , Jennifer L. Ross, Ruxandra I. Dima

1257-Pos Board B359 KATANIN SPIRAL AND RING STRUCTURES SHED LIGHT ON POWER STROKE FOR MICROTUBULE SEVERING. Elena A. Zehr , Agnieszka Szyk, Grzegorz Piszczek, Ewa Szczesna, Xiaobing Zuo, Antonina Roll-Mecak 1258-Pos Board B360 LENGTH-DEPENDENT PERSISTENCE LENGTH FOR MICROTUBULES SHORT- ER THAN 3 MICROMETERS. Gretchen Niederriter , Douglas S. Martin 1259-Pos Board B361 STRUCTURAL TRANSFORMATION OF MICROTUBULES IN THE PRESENCE OF CATIONIC POLYMERS.  Juncheol Lee , Chaeyon Song, Jimin Lee, Herb P. Miller, Leslie Wilson, Cyrus R. Safinya, Myung Chul Choi 1260-Pos Board B362 CONDENSATION OF DIVALENT METAL IONS BY MAP-TAU REMODELS TAU-MICROTUBULE BUNDLE ARCHITECTURE. Bretton Fletcher , Chaeyeon Song, Phillip Kohl, Peter J. Chung, Herbert Miller, Youli Li, Myung Chul Choi, Leslie Wilson, Stuart C. Feinstein, Cyrus R. Safinya 1261-Pos Board B363 HIGHER ORDER ASSEMBLY STRUCTURES OF HUMAN TAU AND MICRO- TUBULES REGULATED BY IONIC STRENGTH. Hasaeam Cho , Jimin Lee, Juncheol Lee, Herbert P. Miller, Keong Sik Jin, Leslie Wilson, Stuart C. Fein- stein, Cyrus R. Safinya, Myung Chul Choi 1262-Pos Board B364 THE EFFECT OF SITE-SPECIFIC ACETYLATION BASED TAU MUTATIONS ON TAU-MICROTUBULE ASSOCIATIONS. Christine Tchounwou , Bretton Fletcher, Chaeyeon Song, Phillip A. Kohl, Peter J. Chung, Herb P. Miller, Youli Li, Myung-Chul Choi, Leslie Wilson, Stuart C. Feinstein, Cyrus R. Safinya 1263-Pos Board B365 PROBING STRUCTURAL FEATURES OF TAU BINDING TO TUBULIN AND MICROTUBULES. Ho Yee Joyce Fung , Elizabeth Rhoades 1264-Pos Board B366 IMPACT OF AC ELECTRIC FIELDS ON MICROTUBULE DYNAMICS IN VI- TRO .  Joseph M. Cleary 1265-Pos Board B367 MICROTUBULE NUCLEATION AND STABILIZATION BY DOUBLECOR- TIN. Szymon W. Manka , Carolyn A. Moores 1266-Pos Board B368 STRUCTURE AND FUNCTION OF SURFACE-BOUND TAU. Zachary J. Donhauser 1267-Pos Board B369 A FIRST-APPROXIMATION ESTIMATE OF FORCES REQUIRED FOR MICRO- TUBULE BREAKAGE. Sharyn A. Endow , Piotr E. Marszalek 1268-Pos Board B370 LONG-RANGE MECHANICAL COUPLING IN THE MICROTUBULE LAT- TICE. Maxim Igaev , Helmut Grubmueller 1269-Pos Board B371 MULTI-SCALE COMPUTATIONAL MODELING OF TUBULIN-TUBULIN INTER- ACTIONS IN MICROTUBULE SELF-ASSEMBLY FROM ATOMS TO CELLS.  Mahya Hemmat , Brian T. Castle, David J. Odde 1270-Pos Board B372 TUBULIN POLYMERIZATION-PROMOTING PROTEIN FAMILY MEMBER 3 (TPPP3) FACILITATES MICROTUBULE BUNDLING AND NETWORK FOR- MATION VIA ITS WEAK INTERACTION WITH MICROTUBULES. Takayuki Torisawa, Shuji Ishihara, Kazuhiro Oiwa 1271-Pos Board B373 KINETOCHORE-MEDIATED MULTIVALENCY OF NDC80 COMPLEX CON- TROLS MICROTUBULE END DYNAMICS AND FORCE-GENERATION.  Vladimir A. Volkov , Pim J. Huis in ’t Veld, Andrea Musacchio, Marileen Dogterom

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