Biophysical Society 65th Annual Meeting Program Guide

Platform Neuroscience 2:00 pm - 3:30 pm

1344-Plat 3:15 pm PROBING THE MEMBRANE ENVIRONMENT OF PLASMA MEMBRANE PROTEINS: A MICROPATTERNING APPROACH. Veronika Brumovska , Gergö Fülöp, Gerhard J. Schütz, Eva Sevcsik Platform Muscle, Calcium and Signaling II 2:00 pm - 3:30 pm Chair Madeline Shea, University of Iowa, USA No Abstract 2:00 pm CA2+-SATURATED CALMODULIN BINDS TIGHTLY TO THE N-TERMINAL DOMAIN OF A-TYPE FIBROBLAST GROWTH FACTOR (FGF) HOMOLOGOUS FACTORS. Madeline Shea 1345-Plat 2:30 pm MULTISCALE MODELING OF DYADIC STRUCTURE-FUNCTION RELATION IN VENTRICULAR CARDIAC MYOCYTES. Filippo Giovanni Cosi, Wolfgang Giese, Wilhelm Neubert , Stefan Luther, Chamakuri Nagaiah, Ulrich Par- litz, Martin Falcke 1346-Plat 2:45 pm QUANTITATIVE ASSESSMENT OF CARDIAC INTERCALATED DISK ULTRA- STRUCTURE AND MOLECULAR ORGANIZATION BY INDIRECT CORRELA- TIVE LIGHT AND ELECTRON MICROSCOPY. Heather Struckman , Nicolae Moise, Celine Dagher, Seth H. Weinberg, Rengasayee Veeraraghavan 1347-Plat 3:00 pm MACHINE LEARNING TECHNIQUES TO CLASSIFY THE SEVERITY OF NOVEL SCN5A VARIANTS. Chiara Campana , Eric A. Sobie 1348-Plat 3:15 pm FUNCTIONAL AND STRUCTURAL INTERACTIONS BETWEEN CA 2+ , ATP AND CAFFEINE BINDING SITES OF SKELETAL MUSCLE RYANODINE RECEPTOR (RYR1). Venkat R. Chirasani , Daniel A. Pasek, Hannah G. Addis, Naohiro Yamaguchi, Gerhard Meissner Platform Actin and Associated Proteins - Myosins 2:00 pm - 3:30 pm Chair Glen Hocky, New York University, USA 1349-Plat 2:00 pm PASSIVE VERSUS ACTIVE REGULATION IN THE ACTIN CYTOSKELETON. Glen M. Hocky 1350-Plat 2:30 pm MYOSIN’S POWERSTROKE OCCURS WITH PHOSPHATE STILL IN THE AC- TIVE SITE. Brent Scott , Christopher Marang, Laura K. Gunther, Mike K. Woodward, Christopher M. Yengo, Edward P. Debold 1351-Plat 2:45 pm STRUCTURE OF THE SHUTDOWN STATE OF MYOSIN-2. Charlotte A. Scarff , Glenn Carrington, David E. Casas-Mao, Joseph M. Chalovich, Peter J. Knight, Neil A. Ranson, Michelle Peckham 1352-Plat 3:00 pm STRUCTURAL PERSPECTIVE INTO ACTIVATION OF ARP2-3 COMPLEX FOR NUCLEATING LINEAR AND BRANCHED ACTIN ASSEMBLIES. Bojian Ding , Heidy Narvaez Ortiz, Brad Nolen, Saikat Chowdhury 1353-Plat 3:15 pm THE ACTIN CYTOSKELETON REGULATES MACROPHAGE ACTIVATION AND INFLAMMATION. Elsa Ronzier , Jeremy D. Rotty

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Chair Guo-Li Ming, University of Pennsylvania, USA 1354-Plat 2:00 pm MODELING HUMAN BRAIN ORGANOGENESIS USING PLURIPOTENT STEM CELLS. Guo-Li Ming 1355-Plat 2:30 pm MARGARIC ACID COUNTERACTS NEURONAL MECHANICAL SENSITIZATION. Luis O. Romero , Rebeca C. Caires Mugarra, Alec R. Nickolls, Alexander T. Chesler, Julio F. Cordero-Morales, Valeria Vasquez 1356-Plat 2:45 pm OPTOGENETIC ACTIVATION OF ERK AND AKT SIGNALING PROMOTES AXON REGENERATION AND FUNCTIONAL RECOVERY IN DROSOPHILA. Qin Wang, Huaxun Fan, Feng Li, Savanna S. Skeeters, Vishnu Krishnamurthy, Yuanquan Song, Kai Zhang 1357-Plat 3:00 pm STOCHASTIC REACTION-DIFFUSION MODELING OF CALCIUM DYNAMICS IN 3D-DENDRITIC SPINES OF PURKINJE CELLS. Victor Nicolai Friedhoff , Gabriela Antunes, Martin Falcke, Fábio Marques Simões de Souza 1358-Plat 3:15 pm TARGETED SENSORS FOR GLUTAMATERGIC NEUROTRANSMISSION. Yuchen Hao , Estelle Toulmé, Benjamin König, Ljudmila Katchan, Andrew J. Plested Platform Spectroscopy, Diffraction and Microscopy 2:00 pm - 3:30 pm Chair Marvin Bayro, University of Puerto Rico, USA 1359-Plat 2:00 pm SOLID-STATE NMR ANALYSIS OF INTERFACE FLEXIBILITY IN PLEOMOR- PHIC PROTEIN ASSEMBLIES. Guivert Michel, Jeremy J. Gonzalez, Carlos A. Figueroa-Morales, Naomi C. Rodriguez, Marvin J. Bayro 1360-Plat 2:30 pm DEEP LEARNING FOR FAST ATOMIC FORCE MICROSCOPY DATA ANALYTICS. Anwesha Sarkar , Joshua Waite, Soumik Sarkar 1361-Plat 2:45 pm COMBINATORIAL METHODS TO ENHANCE SUPERCRITICAL ANGLE FLUORES- CENCE MEASUREMENTS. Aaron Au , Christopher M. Yip 1362-Plat 3:00 pm SUPER RESOLUTION CRYO-EMMAPS WITH 3D DEEP GENERATIVE NET- WORKS. Sai Raghavendra Maddhuri Venkata Subramaniya , Genki Terashi, Daisuke Kihara 1363-Plat 3:15 pm BAYESIAN STRUCTURE DETERMINATION FROM ULTRAFAST SINGLE MOL- ECULE X-RAY DIFFRACTION. Steffen Schultze , Helmut Grubmuller

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