Biophysical Society 65th Annual Meeting Program Guide

1004-Pos B oard B54 COMPARTMENTALIZED SIGNALING WITHIN A LIQUID CRYSTAL REGU- LATES MEIOTIC DNA BREAK REPAIR. Lexy von Diezmann , Ofer Rog 1005-Pos B oard B55 DEVELOPING A FUNCTIONALLY VALID MODEL OF THE TREM2-APOE COMPLEX TO BETTER UNDERSTAND ITS ROLE IN ALZHEIMER’S DIS- EASE. Hunter B. Dean , Thomas J. Brett, Erik D. Roberson, Yuhua Song 1006-Pos B oard B56 UNVEILING THE CONTRIBUTIONS OF SECONDARY STRUCTURE AND DISULFIDE BONDS FOR BACTERIAL ADHESION PILI EXTENSION USING A MULTISCALE APPROACH. Joseph Baker, Tobias Dahlberg, Esther Bullitt , Magnus Andersson 1007-Pos B oard B57 SOLUBILITY PRODUCT CONSTANT GOVERNS MULTIVALENT PROTEIN PHASE SEPARATIONS. Aniruddha Chattaraj , Michael L. Blinov, Leslie M. Loew 1008-Pos B oard B58 A QUANTITATIVE FRAMEWORK FOR HETEROTYPIC BUFFERING ENABLED BY MULTICOMPONENT BIOMOLECULAR CONDENSATES. Furqan Dar , Rohit V. Pappu, J. Paul Taylor 1009-Pos B oard B59 PATHWAYS OF GENOME RELEASE DETERMINED BY VIRION PROPER- TIES. Lukáš Sukeník, Pavel Plevka, Robert Vacha 1010-Pos B oard B60 QUANTIFYING BTUBA/B ASSEMBLY IN LIVING CELLS. Yuhan Wang , Ma- hima Unnikrishnan, Brooke Ramsey, Martin Gruebele 1011-Pos B oard B61 A PIPELINE FOR INTEGRATIVE STRUCTURAL MODELLING OF VERY COM- PLEX MOLECULAR COMPLEXES. Jan Kosinski , Vasileios Rantos, Kai Karius 1012-Pos B oard B62 RESOLVING STRUCTURAL CHANGES IN FIBERS DURING FIBRINOLY- SIS. Spencer R. Lynch , Brittany E. Bannish, Nathan E. Hudson 1013-Pos B oard B63 A MULTIDISCIPLINARY APPROACH TO DESIGN AMYLOID-LIKE PEPTIDES TO FORM SUPRAMOLECULAR ASSEMBLIES. Laura Pérez-Chirinos Lallana , Ivan R. Sasselli, Aitziber L. Cortajarena 1014-Pos B oard B64 TOPOLOGY PROTECTS ROBUST GLOBAL CYCLES IN STOCHASTIC SYS- TEMS. Evelyn M. Tang , Jaime Agudo-Canalejo, Ramin Golestanian 1015-Pos B oard B65 UNRAVELING THE DRIVING FORCES BEHIND THE BIOGENESIS OF BACTE- RIAL MICROCOMPARTMENTS. Gaurav Kumar , Sharmistha Sinha Membrane Protein Structures II (Boards B66 - B81) 1016-Pos B oard B66 ISOTHERMAL TITRATION CALORIMETRIC ANALYSIS OF MEMBRANE PROTEIN-PROTEIN INTERACTIONS; CYTOCHROME B 6 F - FERREDOXIN NADP + REDUCTASE. William A. Cramer , Stanislav D. Zakharov, Genji Kurisu, Yuko Misumi 1017-Pos B oard B67 ELECTROPHYSIOLOGICAL AND BIOCHEMICAL CHARACTERIZATION OF THE HUMAN P2X7B RECEPTOR INXENOPUS LAEVISOOCYTES. Sanaria Hawro Yakoob , Guenther Schmalzing, Fritz Markwardt 1018-Pos B oard B68 STRUCTURE BASIS AND GATING MECHANISM OF CALCIUM HOMEOSTA- SIS MODULATOR 2 CHANNEL. Wooyoung Choi

1019-Pos B oard B69 SYSTEMATIC ANALYSIS OF SYMMETRY IN MEMBRANE PROTEINS. Antoniya A. Aleksandrova , Edoardo Sarti, Emily L. Yaklich, Lucy R. Forrest 1020-Pos B oard B70 UNDERSTANDING THE MECHANISM OF LIPID TRANSPORT THROUGH THE MLA SYSTEM IN E.COLI . Dhenesh Puvanendran , Max Haase, Gira Bhabha, Damian C. Ekiert 1021-Pos B oard B71 BIOPHYSICAL BASIS OF KDEL RECEPTOR-LIPID INTERACTIONS IN SECRE- TORY SIGNALING. Asma Rehman , Amanda Altieri, Wenbo Yu, Stefan M. Ivanov, Brian G. Pierce, Alexander D. MacKerell, Syed Saif Hasan 1022-Pos B oard B72 A FAB-TAG FOR SMALL MEMBRANE PROTEIN STRUCTURE DETERMINA- TION. Benjamin McIlwain , Amanda Erwin, Melanie D. Ohi, Randy B. Stockbridge 1023-Pos B oard B73 EXPLORING THE THREE-DIMENSIONAL ARCHITECTURES OF TWO FAMI- LIES OF LARGE PORE CHANNELS (CALHM1,2 AND PANNEXIN1). Johanna L. Syrjanen , Kevin Michalski, Tsung-Han Chou, Shanlin Rao, Eric Henze, Ju- lia M. Kumpf, Noriko Simorowski, Tim Grant, Nikolaus Grigorieff, Stephen J. Tucker, Toshimitsu Kawate, Hiro Furukawa 1024-Pos B oard B74 REFINEMENT OF THE TRANSMEMBRANE DOMAIN IN CONSTRUCTING THE MEMBRANE-EMBEDDED SARS-COV-2 SPIKE PROTEIN MODEL. Tianle Chen , Karan Kapoor, Emad Tajkhorshid 1025-Pos B oard B75 HOW GPCRS ENGAGE GPCR KINASES IN THE FIRST STEP OF HOMOLO- GOUS DESENSITIZATION. John J. Tesmer , Qiuyan Chen, Manolo Plasencia, Zhuang Li, Leifu Chang, Philip C. Andrews 1026-Pos B oard B76 CHALLENGES WITH THE PREPARATION OF A SOLUBLE AND ACTIVE FORM OF LRAT. Sarah Roy , Line Cantin, Jordan Grondin, Vincent Boulanger, Marie-Eve Gauthier, Stephane M. Gagne, Christian Salesse 1027-Pos B oard B77 THE ANTI-APOPTOTIC BCL-2 PROTEIN BEHAVES AS AN INTEGRAL MEM- BRANE PROTEIN. Ameeq Ul Mushtaq, Jörgen Åden, Tobias Sparrman, Artur P.G. Dingeldein, Hanna P. Wacklin, Luke A. Clifton, Gerhard Grobner 1028-Pos B oard B78 SUBSTRATE RECOGNITION OF THE SMALL MULTIDRUG RESISTANCE (SMR) FAMILY. Olive E. Burata , Christian B. Macdonald, Ali A. Kermani, Randy Stockbridge 1029-Pos B oard B79 STRUCTURE OF THE BACTERIAL LIPID ABC TRANSPORTER MLAFEDB REVEALS SUBSTRATE BOUND. Mark R. MacRae , Nicolas Coudray, Georgia L. Isom, Mariyah N. Saiduddin, Gira Bhabha, Damian C. Ekiert 1030-Pos B oard B80 STRUCTURAL SWITCHES REGULATING THE ALTERNATING ACCESS MECHA- NISM OF HUMAN P-GLYCOPROTEIN. Karan Kapoor , Sepehr Dehgha- nighahnaviyeh, Emad Tajkhorshid 1031-Pos B oard B81 CRYSTAL STRUCTURES OF A MELIBIOSE SYMPORTER MELB WITH BOUND SUGAR SUBSTRATE. Lan Guan , Hariharan Parameswaran Intrinsically Disordered Proteins (IDP) and Aggregates II (Boards B82 - B99) 1032-Pos B oard B82 INVESTIGATION OF DYNAMICS ALONG DIVERGENT TAU AGGREGATION PATHWAYS. Ellie I. James , Abhinav Nath, Miklos Guttman

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