Biophysical Society 66th Annual Meeting Program Guide

1505-Plat 5:45 pm A VIRAL RNA USES CONFORMATIONAL REARRANGEMENTS OF A DY - NAMIC TRNA-LIKE STRUCTURE TO HIJACK CELLULAR MACHINERY. Steve L. Bonilla , Madeline E. Sherlock, Andrea MacFadden, Jeffrey S. Kieft Platform General Protein-Lipid Interactions 4:00 pm - 6:00 pm, South, Level Two, Room 209/210/211 Co-Chairs Tatyana I. Smirnova, North Carolina State University, USA Juan Orjuela, Universidad de los Andes, Colombia 1506-Plat 4:00 pm Travel Award Winner A CONSERVED MEMBRANE-INTEGRAL PYROPHOSPHATASE ANIONIC MEMBRANE FINGERPRINT IDENTIFIED BY MULTI-SCALE MOLECULAR DYNAMICS SIMULATIONS. Alexandra O.M. Holmes , Adrian Goldman, Antreas Kalli 1507-Plat 4:15 pm PROTONATION OF MODEL IONIZABLE SIDECHAINS IN TRANSMEM - BRANE PROTEIN DOMAINS. Tatyana I. Smirnova , Maxim A. Voinov, Gabriel A. Cook, Alex I. Smirnov 1508-Plat 4:30 pm THE INTERPLAY BETWEEN CHOLESTEROL AND AQUAPORIN-0. Juan D. Orjuela , Po-Lin Chiu, Thomas Walz, Bert L. de Groot, Camilo A. Aponte- Santamaria 1509-Plat 4:45 pm A TUNABLE LIPID BILAYER NATIVE MS PLATFORM FOR DIRECT DETERMI - NATION OF HIERARCHICAL ORGANIZATION OF MEMBRANE PROTEINS AND LIPIDS AT THE MEMBRANE. Aniruddha Panda , Fabian Giska, Caroline Brown, Jeff Coleman, James E. Rothman, Kallol Gupta 1510-Plat 5:00 pm DIRECT LIPID-DRUG INTERACTION IN HUMAN MULTIDRUG TRANSPORT - ER ABCG2. Ali Rasouli , Sepehr Dehghanighahnaviyeh, Qin Yu, Po-Chao Wen, Kaspar Locher, Emad Tajkhorshid 1511-Plat 5:15 pm ORGANIZING CELL-FREE EXPRESSED MEMBRANE PROTEINS IN SYN - THETIC MEMBRANES USING LIPID-PROTEIN INTERACTIONS. Justin Peruzzi , Jan Steinkuehler, Timothy Vu, Peilong Lu, David Baker, Neha Kamat 1512-Plat 5:30 pm NEURONAL LIPID RAFTS REGULATE NEUROPATHIC PAIN VIA MODULA - TION OF TRPV1 AND NMDA RECEPTOR MEMBRANE DYNAMICS. Juliana Navia Pelaez , Luciano Capettini, Tony Yaksh, Yury Miller 1513-Plat 5:45 pm STEPWISE AND COOPERATIVE MEMBRANE BINDING AND TETHERING OF EXTENDED SYNAPTOTAGMINS REVEALED BY OPTICAL TWEEZERS. Jinghua Ge , Xin Bian, Lu Ma, Yiying Cai, Yanghui Li, Jie Yang, Erdem Karatekin, Pietro De Camilli, Yongli Zhang Platform Cell Mechanics, Mechanosensing, and Motility 4:00 pm - 6:00 pm, South, Level Two, Room 212/213/214 Co-Chairs Dennis E. Discher, University of Pennsylvania, USA Christina Hueschen, Stanford University, USA 1514-Plat 4:00 pm MECHANOSENSITIVE ION CHANNELS ARE ESSENTIAL FOR THE DURO - TAXIS OF PANCREATIC STELLATE CELLS. Ilka Budde, David Ing, Albrecht Schwab, Zoltan Denes Petho

1515-Plat 4:15 pm HYPOTONIC STRESS TRIGGERS DELAYED CELL VOLUME INCREASE VIA CROSSTALK BETWEEN MYOSIN, CALCIUM SIGNALING, AND ION TRANS - PORT. Qin Ni , Zhouxu Ge, Jinyu Fu, Yufei Wu, Yizeng Li, Sean Sun 1516-Plat 4:30 pm DISTINCT SELF-ORGANIZED ACTIN PATTERNS EXPLAIN DIVERSE PARA - SITE GLIDING MODES. Christina Hueschen , Li-av Segev Zarko, Jian-Hua Chen, Mark LeGros, Carolyn A. Larabell, John C. Boothroyd, Rob Phillips, Alexander R. Dunn 1517-Plat 4:45 pm DYNAMICS OF CELL ADHESION ON FLUID SUBSTRATES. Oleg Mikhajlov , Fahima Di Federico, John Manzi, Fanny Tabarin, Guy Tran van Nhieu, Patricia M. Bassereau 1518-Plat 5:00 pm THE ADIPOCYTE SECRETOME INHIBITS T-CELL ACTIVATION BY DAMPEN - ING T-CELL RECEPTOR MECHANOTRANSDUCTION. Anna V. Kellner , Rae Hunter, Priscilla Do, Miyoung Lee, Jamie Hamilton, Rong Ma, Anthony Ross, Christopher Porter, Erik Dreaden, Curtis Henry, Khalid Salaita 1519-Plat 5:15 pm SCALING RELATIONSHIP BETWEEN PHAGOCYTIC CUP AND ENGULF - MENT FORCES. Megan E. Kern 1520-Plat 5:30 pm ON THE ADHESION-VELOCITY RELATION AND LENGTH ADAPTATION OF MOTILE CELLS ON STEPPED FIBRONECTIN LANES. Martin Falcke , Chris - toph Schreiber, Behnam Amiri, Johannes Heyn, Joachim O. Rädler 1521-Plat 5:45 pm CURVATURE DYNAMICALLY REGULATES CELL MIGRATION MODE AND MOTILITY. Cas van der Putten, Maike Werner, Daniëlle van den Broek, Carlijn Bouten, Nicholas A. Kurniawan Platform Bioenergetics and Mitochondria 4:00 pm - 6:00 pm, South, Level Two, Room 215/216 Co-Chairs Maria Neginskaya, New York University, USA Anthony Watts, University of Oxford, United Kingdom 1522-Plat 4:00 pm ELECTROPHYSIOLOGICAL CHARACTERIZATION OF MITOCHONDRIAL CURRENTS AT THE CONTACT SITE OF THE INNER AND OUTER MEM - BRANE. Gayathri K. Natarajan , James S. Heisner, Amadou K. Camara, Wai-Meng Kwok 1523-Plat 4:15 pm Travel Award Winner HOLOGRAPHIC IMAGING OF THE MITOCHONDRIAL SWELLING IN THE LIVING CELLS REVEALS THAT MITOCHONDRIAL DEPOLARIZATION OC - CURS BEFORE ACTIVATION OF THE HIGH-CONDUCTANCE PERMEABILITY TRANSITION PORE. Maria A. Neginskaya , Sally E. Morris, Evgeny V. Pavlov 1524-Plat 4:30 pm SMALL MOLECULES TARGETING THE VDAC-NADH BINDING POCKET MODULATE MITOCHONDRIAL METABOLISM IN CANCER CELLS. Kareem A. Heslop , Pieter Burger, Monika Gooz, Amandine Rovini, Thomas Ben - ton, Catherine Mills, Patrick Woster, Eduardo N. Maldonado 1525-Plat 4:45 pm LIPIDS AND DIVALENT CATIONS REGULATE BH3-INDEPENDENT ACTIVA - TION OF BAX AND BCL-XL. Victor Vasquez Montes, Mykola V. Rodnin, Alexey S. Ladokhin

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