Biophysical Society 66th Annual Meeting Program Guide

Protein Structure and Conformation III (Boards B1 - B18) 1543-Pos Board B1 MECHANISM OF TRANSLOCATION BY BACTERIOPHAGE T7 HELICASE GP4 USING AWSEM-SUITE. Shikai Jin , Carlos A. Bueno Basurco, Wei Lu, Yang Gao, Peter G. Wolynes 1544-Pos Board B2 TOPOLOGICAL ANALYSIS OF HIGH TEMPERATURE ENZYME ACTIVITY. Samin Tajik 1545-Pos Board B3 NMR ILLUMINATES THE LIGAND AND SURFACE ADSORPTION OF AUTOLY - SIN-AMIDASE FROM STAPHYLOCOCCUS EPIDERMIDIS . Rahul Yadav , Radha P. Somarathne, Shen Yang, Park J. Youn, Nicholas C. Fitzkee 1546-Pos Board B4 OPTIMIZATION OF A PROCESSING AND ANALYSIS WORKFLOW FOR PROTEOME-WIDE STRUCTURAL BIOLOGY. Raquel L. Shortt , Lisa M. Jones, Lindsay Pino 1547-Pos Board B5 ALTERED PROTEIN DYNAMICS AND TRANSITION KINETICS DELINEATE THE ONCOGENIC POTENTIAL IN MUTATED KINASES. Keshav Patil , Stanislav Shvartsman, Ravi Radhakrishnan 1548-Pos Board B6 COMPARING SAXS MODELLING APPROACHES ON STRUCTURAL TRANSI - TIONS IN CALMODULIN PROTEIN MEASURED AT HIGH-THROUGHPUT LIX BEAMLINE. Shirish N. Chodankar , James Byrnes, Lin Yang 1549-Pos Board B7 PREDICTING THE FUNCTIONAL STATE OF PROTEIN KINASES USING IN - TERPRETABLE GRAPH NEURAL NETWORKS. Ashwin Ravichandran , Juan Araque, John Lawson 1550-Pos Board B8 GAP POSITIONS CATALYTIC H-RAS RESIDUE Q61 FOR GTP HYDROLYSIS IN MD SIMULATIONS. Lara A. Patel , Timothy J. Waybright, Andrew G. Stephen, Chris Neale 1551-Pos Board B9 LARGE SCALE ALL-ATOMMOLECULAR DYNAMICS SIMULATIONS OF MUTANT CA TUBES PROVIDE INSIGHTS ON CYTOTOXIC T-LYMPHOCYTE- MEDIATED HIV-1 RESTRICTION. Alexander J. Bryer , Muthukumar Balasu - bramaniam, Santosh Thapa, Benem-Orom Davids, Chaoyi Xu, Jiong Shi, Christopher Aiken, Jui Pandhare, Chandravanu Dash, Juan R. Perilla 1552-Pos Board B10 USING BIOMOLECULAR SIMULATIONS TO INTERPRET EXPERIMENTAL DATA. Alexander H. Schug 1553-Pos Board B11 Travel Award Winner HIDDEN STRUCTURE IN DISORDERED PROTEINS IS ADAPTIVE TO CHANG - ES IN THE CELLULAR ENVIRONMENT. David Moses , Karina Guadalupe, Feng Yu, Alex S. Holehouse, Shahar Sukenik 1554-Pos Board B12 ATOMISTIC SIMULATION OF MUTATION EFFECT ON THE HIERARCHI - CAL STRUCTURE AND MECHANICS OF HUMAN EPITHELIAL KERATIN K1/ K10. Chia-Ching Chou , Tzu-Lun Huang, Chien-Yu Pan 1555-Pos Board B13 MULTI-MICROSECOND MOLECULAR DYNAMICS UNVEILS THE MECHA - NISM OF DNA TRAVERSAL WITHIN CRISPR-CAS12A. Aakash Saha , Pablo R. Arantes, Mohd Ahsan, Martin Jinek, Giulia Palermo

1556-Pos Board B14 MODELING AND SIMULATION OF FULLY-GLYCOSYLATED FULL-LENGTH HIV ENVELOPE PROTEIN EMBEDDED IN A VIRAL MEMBRANE. Yiwei Cao , Board B15 PROTSUBS: A SERIES OF SUBSTITUTION MATRICES REFLECTING RELA - TIONSHIPS BETWEEN PROTEIN EVOLUTION AND STRUCTURE. Kejue Jia , Mesih Kilinc, Benjamin R. Litterer, Robert L. Jernigan 1558-Pos Board B16 DEVELOpmENT OF PDB CLEANING SCRIPT FOR CHARMM GUI ERROR REDUCTION. Turner P. Brown , Wonpil Im, Jumin Lee 1559-Pos Board B17 EXAMINING ENRICHMENT OF PROTEIN ENTANGLEMENT NEAR FUNC - TIONAL SITES. Viraj Rana 1560-Pos Board B18 AGGREGATION SICKLE HEMOGLOBIN. Vinchencia Anderson , Pranav M. Khade, Ambuj Kumar, Kejue Jia, Robert L. Jernigan Protein Stability, Folding, and Chaperones II (Boards B19 - B39) 1561-Pos Board B19 HIGH THROUGHPUT EXPERIMENTAL DETERMINATION OF MINI-PROTEIN LOCAL STABILITY AND FLUCTUATION. Jane Thibeault , Sugyan Dixit, Állan Ferrari, Robert W. Ludwig, Gabriel J. Rocklin 1562-Pos Board B20 ASSEMBLY PRINCIPLES OF THE HUMAN R2TP CHAPERONE COMPLEX REVEALTHE PRESENCE OF R2T AND R2P COMPLEXES. Walid A. Houry 1563-Pos Board B21 STRUCTURAL BASIS FOR CLIENT ENGAGEMENT AND CHAPERONE CY - CLING BY HUMAN MITOCHONDRIAL HSP60. Julian R. Braxton , Jason E. Gestwicki, Daniel R. Southworth 1564-Pos Board B22 STRUCTURAL DYNAMICS OF SUBSTRATE PROCESSING BY THE PAN- PROTEASOME COMPLEX IN SOLUTION: A TIME-RESOLVED SMALL ANGLE NEUTRON SCATTERING STUDY. Frank R. Gabel 1565-Pos Board B23 INVESTIGATING THE MOLECULAR MECHANISM OF A PH SENSITIVE PRO - TEOME. Brandon Czowski , Katharine A. White 1566-Pos Board B24 AN INVESTIGATION OF THE YIDC-MEDIATED MEMBRANE INSER - TION OF PF3 COAT PROTEIN USING MOLECULAR DYNAMICS SIMU - LATIONS. Adithya Polasa , Jeevapani J. Hettige, kalyan immadisetty, Mahmoud Moradi 1567-Pos Board B25 PH EFFECTS ON THE STABILITY AND FOLDING OF MONOMERIC CASPAS - ES. Isha Joglekar 1568-Pos Board B26 SYSTEMATIC DISCOVERY OF NON-NATIVE PROTEIN CONFORMATIONS AND THEIR MOLECULAR AND CELLULAR PHENOTYPES. Eugene Serebryany , Victor Y. Zhao, Sunia A. Trauger, Bogdan Budnik, Eugene I. Shakhnovich 1569-Pos Board B27 CONFORMATIONAL FLEXIBILITY IS A KEY DETERMINANT OF THE LYTIC ACTIVITY OF THE PORE FORMING PROTEIN, CYTOLYSIN A. Avijeet Kulshrestha , Satyaghosh Maurya, Twinkle Gupta, Rahul Roy, Sudeep Pun - nathanam, Ganapathy Ayappa Wonpil Im 1557-Pos

T U

E S

D A Y

106