Biophysical Society 66th Annual Meeting Program Guide

Protein Assemblies (Boards B40 - B72)

1570-Pos Board B28 STRUCTURAL AND MECHANISTIC STUDIES OF SKD3 (HUMAN CLPB ) PRO - VIDE INSIGHT INTO DISEASE-CAUSING MUTATIONS AND REVEAL UNIQUE AAA+ OLIGOMERIZATION. Alexandrea Rizo , Ryan R. Cupo, James Shorter, Daniel R. Southworth 1571-Pos Board B29 DEVELOPING LARGE-SCALE MOLECULAR STABILITY ENGINES FOR CLINI - CAL VARIANT INTERPRETATION. John M. Nicoludis , Gabor F. Ptacek, Jeanne Morin-Leisk, Alexandre Colavin, Carlos L. Araya 1572-Pos Board B30 Travel Award Winner ACUTE DOSES OF IONIZING RADIATION EXTENSIVELY MODIFIES HUMAN ΓS-CRYSTALLIN WITHOUT DESTRUCTION OF OVERALL PROTEIN FOLD. Megan A. Rocha , Brenna Norton-Baker, Jessica Granger-Jones, Dmitry Fishman, Rachel W. Martin 1573-Pos Board B31 PROTEIN EQUILIBRIUM POPULATION SNAPSHOT HYDROGEN DEUTE - RIUM EXCHANGE ELECTROSPRAY IONIZATION MASS SPECTROMETRY MEASUREMENTS OF THE STABILITY OF WILDTYPE HUMAN ACIDIC FIBROBLAST GROWTH FACTOR AND THE R136D VARIANT. Motolani O. Matthew , Jackson Lay Jr., Rohana Liyanage 1574-Pos Board B32 ELECTROMAGNETIC FIELD EXPOSURE INCREASES THE PROTEIN MISFOLD - ING IN VIVO . Huiyong Lian, Xinyu Yue , Jia Yan, qingdai Liu 1575-Pos Board B33 BUILDING A MIMETIC SYSTEM FOR UNRAVELING PROTEIN-PROTEIN INTERACTIONS ON MEMBRANES. Shahenda Ramadan , Paula Guerrero, Ruslan Nedielkov, Nikolai Klishin, Rumiana Dimova, Daniel Varon Silva, Heiko Möller 1576-Pos Board B34 TO REFOLD OR NOT TO REFOLD: FIRST GENERATION UNDERGRADUATE STUDENTS STUDY REFOLDING ACROSS THE TREE OF LIFE. Philip To , Ernes - to Alvarez, Liesel Arauz Vallecillo, Muhammad Bennani, Zanya Jamieson, Leeker Lin, Madelynn Piona, Atharva Bhagwat, Haley M. Moran, Haley Tarbox, Stephen D. Fried 1577-Pos Board B35 MUTATIONS PROTECTIVE AGAINST PRION DISEASE REDIRECT THE FOLD - ING PATHWAY OF PRP IN SINGLE-MOLECULE TRAJECTORIES. Shubhadeep Patra , Uttam Anand, Craig R. Garen, Michael T. Woodside 1578-Pos Board B36 ENGINEERING ROBUST CHAPERONE SUBSTRATES FOR REFOLDING STUD - IES USING THE HIGHLY BIOLUMINESCENT PROTEIN NANOLUC. Dimitra Apostolidou , Piotr E. Marszalek 1579-Pos Board B37 PROBING CHARGED AMINOACID SIDECHAINS IN PROTEIN-PROTEIN INTERFACES USING NMR. Soumya P. Behera , Mark Petersen, Ananya K. Majumdar, Doug Barrick 1580-Pos Board B38 GETTING FRIENDLY WITH DENATURANTS: A UNIQUE TALE OF THE CY - TOPLASMIC DOMAIN OF THE MGTE MAGNESIUM CHANNEL. Rupasree Brahma , H. Raghuraman 1581-Pos Board B39 HOLOTOXIN DISASSEMBLY BY PROTEIN DISULFIDE ISOMERASE IS LESS EF - FICIENT FOR ESCHERICHIA COLI HEAT-LABILE ENTEROTOXIN THAN CHOL - ERA TOXIN. Albert A. Serrano , Jessica Guyette, Joel B. Heim, Michael P. Taylor, Patrick Cherubin, Ute Krengel, Kenneth Teter, Suren A. Tatulian

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1582-Pos Board B40 A MULTISCALE COARSE-GRAINED MODEL OF THE NUCLEAR PORE COM - PLEX AND HIV-1 CAPSID INTERACTION. Arpa Hudait , Gregory A. Voth 1583-Pos Board B41 NANODISSECTION OF THE SARCOMERIC M-LINE COMPLEX USING ATOMIC FORCE MICROSCOPY. Dominik Sziklai , Zsolt Martonfalvi, Miklós S. Kellermayer 1584-Pos Board B42 A MODEL TO ANALYZE HETEROTRIMER FORMATION BY ITC. Cyril B.R. Cook , Doug Barrick 1585-Pos Board B43 QUANTITATIVE MASS SPECTROMETRIC ASSAY OF N-TERMINALLY TRUN - CATED AND PYROGLUTAMYLATED AMYLOID BETA PEPTIDES IN HUMAN BRAIN WITH ALZHEIMER'S DISEASE. Hiroaki Komatsu , Paul H. Axelsen 1586-Pos Board B44 HDX-MS INDICATES THAT STABILIZATION OF THE CATALYTIC DOMAIN IS KEY TO CONTROLLING KINASE ACTIVITY OF CHEA IN BACTERIAL CHE - MOTAXIS. Thomas Tran, Aruni Karunanayake Mudiyanselage, Stephen J. Eyles, Lynmarie K. Thompson 1587-Pos Board B45 Travel Award Winner STRUCTURE OF UNMODIFIED AND PYROGLUTAMYLATED AMYLOID BETA PEPTIDES IN LIPID MEMBRANES. Rowan Hassan , Faisal Abedin, Suren A. Tatulian 1588-Pos Board B46 COMPARATIVE ANALYSIS OF NON-STRUCTURAL PROTEIN 1 DOMAIN-DO - MAIN INTERACTIONS IN H5N1 AND H6N6 INFLUENZA A VIRUSES. James E. Gonzales , Jie Shi, Jae-Hyun Cho, Wonmuk Hwang 1589-Pos Board B47 ONE-STEP CONSTRUCTION OF CIRCULARIZED NANODISCS USING SPYCATCHER-SPYTAG. Qian Ren , Huan Bao 1590-Pos Board B48 STRUCTURAL BASIS FOR TARGET SITE SELECTION IN RNA-GUIDED DNA TRANSPOSITION SYSTEMS. Jung-Un Park, Amy W-L. Tsai , Eshan Meh - rotra, Michael T. Petassi, Shan-Chi Hsieh, Ailong Ke, Joseph E. Peters, Elizabeth H. Kellogg 1591-Pos Board B49 MOLECULAR DYNAMIC SIMULATIONS OF HYDROPHOBINS: PURE-PRO - TEIN BILAYERS AND LIPID-PROTEIN INTERACTIONS. Leonhard J. Starke , Jochen S. Hub 1592-Pos Board B50 STUDYING THE DYNAMICS OF HUMAN SHELTERIN PROTEIN ASSEMBLY ON LONG TELOMERIC DNA AND THEIR ROLES IN TELOMERASE RECRUIT - MENT USING COMBINED SINGLE-MOLECULE MANIPULATION AND IMAG - ING. Joshua A. Kraus , Joana Pashaj, Juliet Arzumanyan, Wanting Wei, Xiuhua Lin, Ci Ji Lim 1593-Pos Board B51 ASSEMBLY OF S. CEREVISIAE POLYMERASE ZETA. Kerry S. McPherson , Dmitry M. Korzhnev 1594-Pos Board B52 PROGRAMMABLE MEMBRANE ATTACK COMPLEX. Wachara Chanakul , Alesandro Laniro, Michael Mayer 1595-Pos Board B53 INTERPLAY OF DYNAMICS AND STABILITY IN THE ASSEMBLY OF THE NEDD4-AMOTL1 COMPLEX. Amber Vogel , MatthewMcWhorter, Afua Nyarko

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