Biophysical Society 66th Annual Meeting Program Guide

1596-Pos Board B54 MULTISCALE SIMULATIONS OF VIRUSES. Alvin Yu , Elizabeth M.Y. Lee, John Briggs, Barbie K. Ganser-Pornillos, Owen Pornillos, Gregory A. Voth 1597-Pos Board B55 DETERMINING THE ROLE OF THE COUPLING PROTEIN CHEW IN SIGNAL TRANSDUCTION OF CHEMORECEPTOR COMPLEXES USING SOLID-STATE NMR. Jessica Allen , Lynmarie K. Thompson 1598-Pos Board B56 CRYO-ELECTRON TOMOGRAPHY OF IN VIVO RECONSTITUTED SARS-COV-2 REPLICATION/TRANSCRIPTION ORGANELLES. Cosmo Z. Buffalo , James H. Hurley 1599-Pos Board B57 BETA-BARREL MODELS OF OLIGOMERS, PROTOFIBRILS, LIPOPROTEINS, AND TRANSMEMBRANE CHANNELS FORMED BY AMYLOID BETA (AL - ZHEIMER’S DISEASE), SYNUCLEINS (PARKINSON’S DISEASE), AND AMYLIN (TYPE 2 DIABETES). Stewart R. Durell, Homer R. Guy 1600-Pos Board B58 UNEXPECTED CONTROL OF PROTEIN SELF-ASSOCIATION BY TRANSLA - TION INITIATION. Shriram Venkatesan , Jeffrey Lange, Brooklyn Lerbakken, Corentin Largeau, Jay R. Unruh, Dai Tsuchiya, Selene Swanson, Laurence A. Florens, Brian D. Slaughter, Randal Halfmann 1601-Pos Board B59 RELATIONSHIPS BETWEEN RNA TOPOLOGY AND NUCLEOCAPSID STRUC - TURE IN A MODEL ICOSAHEDRAL VIRUS. Laurent Marichal, Laetitia Gar - gowitsch, Rafael Leite Rubim, Christina Sizun, Kalouna Kra, Stéphane Bres - sanelli, Yinan Dong, Sanaz Panahandeh, Roya Zandi, Guillaume Tresset 1602-Pos Board B60 LARGE SELF-ASSEMBLED CLATHRIN LATTICES SPONTANEOUSLY DISASSEM - BLE WITHOUT SUFFICIENT ADAPTOR PROTEINS. Sikao Guo , Alexander J. Sodt, Margaret E. Johnson 1603-Pos Board B61 RECONSTITUTION OF AN INTACT CLOCK REVEALS MECHANISMS OF CIRCADIAN TIMEKEEPING. Andy LiWang , Archana G. Chavan, Jeffrey A. Swan, Joel C. Heisler, Cigdem Sancar, Dustin Ernst, Mingxu Fang, Clive R. Bagshaw, Sarvind Tripathi, Priya Crosby, Susan S. Golden, Carrie L. Partch 1604-Pos Board B62 TRUNCATED TITIN IS INCORPORATED INTO THE SARCOMERE IN HUMAN CARDIAC SAMPLES WITH DILATED CARDIOMYOPATHY. Dalma Kellermayer , Hedvig Tordai, Tamás Radovits, Béla Merkely, Miklós S. Kellermayer 1605-Pos Board B63 BIOCHEMICAL EVIDENCE FOR A HETEROTRIMERIC ASSEMBLY OF P2X4 AND P2X7 SUBUNITS. Sanaria Hawro Yakoob 1606-Pos Board B64 AAA+ REGULATOR MUB DISTORTS DNA TO DRIVE FORWARD TRANSPOSI - TION. Eshan Mehrotra , Amy Tsai, Elizabeth H. Kellogg 1607-Pos Board B65 THE ROLE OF THE OSTEOCALCIN-OSTEOPONTIN PROTEIN COMPLEX IN BONE BIOMECHANICS: A KEY CONTRIBUTOR TO ENERGY DISSIPATION AT MINERAL-MINERAL INTERFACES. Mehdi Tavakol , Ted Vaughan 1608-Pos Board B66 CHARACTERIZATION OF ESCRTS PROTEINS ENCODED BY ASGARD ARCHAEA HIGHLIGHTS EVOLUTIONARY CONSERVED FEATURES OF THE ESCRT-III COMPLEX. Natalie Elia 1609-Pos Board B67 DEVELOPING LECTINS AS INHIBITORS OF SARS-COV2. Alex J. Guseman , Linda Murphy, Sham Nambulli, Fatema Bhinderwhala, Paul Duprex, An - gela M. Gronenborn

1610-Pos Board B68 MONITORING THE HEPATITIS B VIRAL (HBV) CAPSID ASSEMBLY BY CHARGE TRANSFER SPECTROSCOPY. Shah Ekramul Alom , Hugues de Rocquigny, Rajaram Swaminathan 1611-Pos Board B69 UNRAVELLING STRUCTURAL ORGANIZATION OF INDIVIDUAL Α-SYNUCLEIN OLIGOMERS GROWN IN THE PRESENCE OF PHOSPHOLIP - IDS. Dmitry Kurouski 1612-Pos Board B70 ARCHITECTURE AND SELF-ASSEMBLY OF THE JUMBO PHAGE NUCLEUS- LIKE COMPARTMENT. Thomas G. Laughlin , Amar Deep, Amy M. Prichard, Christian Seitz, Yajie Gu, Eray Enustun, Sergey Suslov, Kanika Khanna, Erica A. Birkholz, Emily Armbruster, Rommie E. Amaro, Joe Pogliano, Kevin D. Corbett, Elizabeth Villa 1613-Pos Board B71 DECIPHERING THE MOLECULAR ORGANIZATION OF GET PATHWAY CHAP - ERONES THROUGH NATIVE TOP-DOWN DISSOCIATION OF MULTI-PROTEIN COMPLEXES . Fabian Giska , MalaiyalamMariappan, Moitrayee Bhattacha - ryya, Kallol Gupta 1614-Pos Board B72 THE SPIKE-ACE2 INTERACTION UNDERLYING SARS-COV-2 INFECTION AND INHIBITION IS ENHANCED BY INTERMOLECULAR CROSS LINKING. Roi Asor , Anna Olerinyova, Manish S. Kushwah, Fabian Soltermann, Lucas Powell Rudden, Snežana Vasiljevic, Juliane Brun, Mario Hensen, Michelle Hill, Matteo Degiacomi, Nicole Zitzmann, Weston B. Struwe, Philipp Kukura Protein Dynamics and Allostery I (Boards B73 - B104) 1615-Pos Board B73 MOLECULAR DYNAMICS SIMULATION STUDY OF THE TCRΓΔ-CD1D- SULFATIDE COMPLEX. Sofiya B. Bettencourt , Robert J. Mallis, Matthew J. Lang, Ellis L. Reinherz, Wonmuk Hwang 1616-Pos Board B74 SIMULATING THE BINDING OF A T CELL RECEPTOR TO A PEPTIDE-BOUND MAJOR HISTOCOMPATIBILITY COMPLEX. Erin Brossard , Steven A. Corcelli 1617-Pos Board B75 EXPLORING THE RECOGNITION DIFFERENCES OF PEPTIDES IN TCR-pmHC COMPLEX. Elif Naz Bingol, Pemra Ozbek 1618-Pos Board B76 UNDERSTANDING S100B ALLOSTERY FROM A DYNAMICAL AND STRUC - TURAL PERSPECTIVE USING MOLECULAR DYNAMICS SIMULATIONS. Riya Samanta , David J. Weber, Silvina Matysiak 1619-Pos Board B77 THE N-TERMINUS OF MIF CONTROLS THE FLEXIBILITY OF SPECIFICΒ- SHEET RESIDUES RESULTING IN DYNAMIC REGULATION OF CD74 ACTIVA - TION. Andrew Parkins , Erin Skeens, C. Michael McCallum, George Lisi, Georgios Pantouris 1620-Pos Board B78 A DISORDERED LINKER WITH "SOMETHING" ON ITS N-TERMINUS DRIVES THE ALLOSTERY IN THE UROKINASE-TYPE PLASMINOGEN ACTIVATOR (UPA). Constanza Torres-Paris , Harriet J. Song, Lufan Xiao, Elizabeth A. Komives 1621-Pos Board B79 RPS3 ENHANCES FULL-LENGTH NFKB-DNA BINDING THROUGH TERNARY COMPLEX FORMATION. Francis X. Alipranti , Hannah E. E.R. Baughman, Elizabeth A. Komives

T U

E S

D A Y

108