Biophysical Society 66th Annual Meeting Program Guide

1635-Pos Board B93 HYDROGEN-DEUTERIUM EXCHANGE OF PLASMA-DERIVED VON WILL - EBRAND FACTOR REVEALS SIMILAR DYNAMICS TO ISOLATED A1 DOMAIN AND AUTOINHIBITORY MODULE. Emily R. Legan , Moriah S. Wilson, Nicholas A. Arce, Ernest T. Parker, Pete Lollar, Renhao Li 1636-Pos Board B94 POSSIBLE ROUTES FOR INHIBITING EXTREME MECHANOSTABILITY OF STAPH ADHESINS DURING BIOFILM FORMATION. Priscila F.C. Gomes , Marcelo Cardoso dos Reis Melo, Rafael C. Bernardi 1637-Pos Board B95 TWO-PHOTON FLUORESCENCE DEPOLARIZATION DYNAMICS OF IONIC STRENGTH BIOSENSORS. Rowan D. Simonet , Malachy Brink, Sarah Mersch, Cody Staydohar, Arnold J. Boersma, Erin D. Sheets, Ahmed A. Heikal 1638-Pos Board B96 CHARACTERIZING THE BINDING DYNAMICS OF CYCLIC-G/AMP SYN - THASE (CGAS) TO NUCLEOSOMES WITH SINGLE-MOLECULE RESOLU - TION. Raquel Merino Urteaga , Alex Strom, Xinyu A. Feng, Jungsan Sohn, Board B97 LINKING TRANSLATION FACTOR CONFORMATIONAL DYNAMICS WITH TRANSLATION EFFICIENCIES AND GENE EXPRESSION. Linda Krause, Anir - ban Chakraborty, Alexandra Z. Andreou, Dagmar Klostermeier 1640-Pos Board B98 REGULATION OF THE CATALYTIC ACTIVITY OF BY-KINASES. Fatlum Hajredini , Ranajeet Ghose 1641-Pos Board B99 DIFFERENCES IN SELF-ASSEMBLY OF THE INFLAMMASOME ADAPTOR ISOFORM ASC AND ASCB: INSIGHTS INTO INFLAMMASOME REGULA - TION. Pedro Diaz-Parga , Eva de Alba 1642-Pos Board B100 TRACKING DOMAIN CLOSING IN THE ADENYLATE KINASE REAC - TION. Fredrik Orädd, Harsha Ravishankar, Per Rogne, Lars Backman, Mi - chael Wulff, Matteo Levantino, Magnus Wolf-Watz, Magnus Andersson 1643-Pos Board B101 MAPPING THE CONFORMATIONAL ENERGY LANDSCAPE OF ABL KINASE USING CLYA NANOPORE TWEEZERS. Fanjun Li , Kaitlyn Gilliam, Ryan Pham, Min Chen 1644-Pos Board B102 Travel Award Winner EXPLORING THE MOLECULAR MECHANISM OF PIP2-REGULATED STEROL TRANSPORT BY STARD4. Hengyi Xie , Ambrose Plante, Ekaterina D. Kots, Harel Weinstein 1645-Pos Board B103 DRUG BINDING ALTERS PATHWAYS OF INFORMATION FLOW IN ERK2. Kaitlin M. Kriefall , Daniel A. Barr 1646-Pos Board B104 CALMODULIN BINDS CONSERVED MOTIFS IN FIBROBLAST GROWTH FAC - TOR HOMOLOGOUS FACTORS. Cade R. Rahlf , Ryan W. Mahling, Holly M. Isbell, Madeline A. Shea Membrane Protein Structures I (Boards B105 - B122) 1647-Pos Board B105 ASSEMBLY OF SEROTONIN RECEPTOR ION CHANNEL 5-HT3A. Bianca Introini , Misha Kudryashev Taekjip Ha 1639-Pos

1622-Pos Board B80 THE SIMULATION STUDY OF THE DIFFERENCES BETWEEN CRISPR TYPE I-E CAS AND TYPE I-F CAS SYSTEMS AND THE INTERACTION BETWEEN THE GUIDE RNA AND DNA. Naoyuki Miyashita , Lisa Matsukura 1623-Pos Board B81 DYNAMIC MECHANISMS OF G-PROTEIN-COUPLED RECEPTOR ALLOSTE - RY. Yinglong Miao 1624-Pos Board B82 CLOSING THE NEGATIVE FEEDBACK LOOP: A TANDEM ATPASE KEEPS CIRCADIAN TIME BY COUPLING DISTANT ENZYMATIC ACTIVITIES. Jeffrey A. Swan , Colby R. Sandate, Alfred M. Freeberg, Joel C. Heisler, Diana L. Etwaru, Cigdem Sancar, Dustin C. Ernst, Joseph G. Palacios, Clive R. Bagshaw, Archana G. Chavan, Susan S. Golden, Andy LiWang, Gabriel C. Lander, Carrie L. Partch 1625-Pos Board B83 CORRELATION BETWEEN PROTEIN CONFORMATIONAL FLEXIBILITY AND LIGAND BINDING INVESTIGATED BY NMR DYNAMICS. Zichun Li , Xiyao Cheng, Meng Gao, Yongqi Huang, Zhengding Su 1626-Pos Board B84 NETWORK INFERENCE APPROACH TO EXTRACT INFORMATION FROM PROTEIN MOLECULAR DYNAMICS. Jenny Liu , Luis Amaral, Sinan Keten 1627-Pos Board B85 MODELLING CONFORMATIONAL DYNAMICS OF ENZYMES TRAPPED IN A PLASMONC HOTSPOT. Alessandro Ianiro , Cuifeng Ying, Edona Karakaci, Anirvan Guha, Michael Mayer 1628-Pos Board B86 STRUCTURAL DYNAMICS WITHIN CONDENSATION DOMAINS DRIVE ALLOSTERIC COMMUNICATION IN NONRIBOSOMAL PEPTIDE SYNTHE - TASES. Subrata H. Mishra , Aswani K. Kancherla, Kenneth A. Marincin, Guillaume Bouvignies, Santrupti Nerli, Nikolaos Sgourakis, Daniel Dowl - ing, Dominique P. Frueh 1629-Pos Board B87 MECHANISM OF DREAM OLIGOMERIZATION KINETIC STUDY. Maria D Santiago , Jaroslava Miksovska 1630-Pos Board B88 MECHANISM OF PEPTIDE ALLOSTERIC MODULATOR BINDING TO CXCR4 CHEMOKINE RECEPTOR REVEALED FROM ACCELERATED MOLECULAR SIMULATIONS. Shristi Pawnikar 1631-Pos Board B89 AFFECTING ANTIBODY-ANTIGEN BINDING AFFINITY THROUGH DYNAMIC ALLOSTERIC MUTATIONS. Lonnie Baker , Donald J. Jacobs 1632-Pos Board B90 EXAMINING THE DONOR EFFECT ON FRET EFFICIENCY IN MACROMO - LECULAR CROWDING SENSORS. Malachy Brink , Rowan D. Simonet, Sarah Mersch, Sarah Bergman, Arnold J. Boersma, Erin D. Sheets, Ahmed A. Heikal 1633-Pos Board B91 STRUCTURE AND DYNAMICS OF THE ACYL CARRIER PROTEIN LINKER IN THE FUNGAL FATTY ACID SYNTHASE. Florian Leidner , Helmut Grubmuller 1634-Pos Board B92 COMPREHENSIVE VIRTUAL SCREENING OF 4.8 K FLAVONOIDS REVEALS NOVEL INSIGHTS INTO THE ALLOSTERIC INHIBITION OF SARS-COV-2 M PRO . Ana Paula Vargas Ruiz , Gabriel Jiménez Avalos, Nicolás E. Delgado, Gustavo Olivos Ramírez, Patricia Sheen, Miguel Quiliano, Mirko Zimic

T U

E S

D A Y

109