Biophysical Society 66th Annual Meeting Program Guide

1648-Pos Board B106 MOLECULAR DETERMINANTS OF DESENSITIZATION OF MGLUR3 BY Β-ARRESTINS. Dagan C. Marx , Alexa Strauss, Nohely Abreu, Joon Lee, David Eliezer, Josh T. Levitz 1649-Pos Board B107 INTRICACIES OF THE SARS-COV-2 SPIKE TRANSMEMBRANE TRIMER OR - GANIZATION. Elena T. Aliper, Nikolay A. Krylov, Anton A. Polyansky, Roman G. Efremov 1650-Pos Board B108 ENSEMBLE-BASED, GLYCAN-DEPENDENT EPITOPE ANALYSIS OF SARS- COV-2 SPIKE PROTEIN. Tianle Chen , Karan Kapoor, Emad Tajkhorshid 1651-Pos Board B109 DETOXIFICATION OF BEE VENOMMELITTIN TO CREATE A SELECTIVE PORE-FORMING PEPTIDE BY SUBSTITUTION OF KEY AMINO ACIDS. Leisheng Sun , Kalina Hristova, William C. Wimley 1652-Pos Board B110 Travel Award Winner PEPTIDE TAGS AND DOMAINS FOR EXPRESSION AND DETECTION OF MAMMALIAN MEMBRANE PROTEINS AT THE CELL SURFACE. Valeria Jaramillo-Martinez , Ina Urbatsch, Vadivel Ganapathy 1653-Pos Board B111 ANTIBODY COMPLEXATION WITH SMALL HELICAL-MPER EPITOPE FOR STRUCTURAL STUDIES OF SMALL MEMBRANE PROTEINS. Chia-Yu Kang , Benjamin C. McIlwain, Randy Stockbridge 1654-Pos Board B112 MAGNETICALLY ALIGNED PEPTOID-BASED MACRODISCS FOR STRUCTURE DETERMINATION OF MEMBRANE PROTEINS BY SOLID-STATE NMR. Aza - mat Galiakhmetov, Richard J.A. Esteves, Emmanuel Awosanya, Quibria A.E. Guthrie, Carolynn Davern, Caroline Proulx, Alexander Nevzorov 1655-Pos Board B113 ISOTHERMAL TITRATION CALORIMETRY OF MEMBRANE PROTEIN INTER - ACTIONS; FNR AND THE CYTOCHROME B6F COMPLEX. William A. Cramer 1656-Pos Board B114 AN ADVANCED YEAST MODEL TO INVESTIGATE THE INTERPLAY BETWEEN STRUCTURE AND FUNCTION OF HUMAN GAMMA-SECRETASE AND ITS SUBSTRATES. Martin Ortner , Walter Stelzer, Fabian Schmidt, Markus Guetlich, Dieter Langosch 1657-Pos Board B115 UNDERSTANDING THE CLUSTERING OF GLYCINE RECEPTORS IN NEURO - TRANSMISSION. Weiwei Wang 1658-Pos Board B116 STRUCTURAL CHARACTERIZATION OF THE TRIPARTITE COMPLEX SERINC5 - ADAPTOR PROTEIN 2 - HIV NEF. Joana Paulino , Alisa Bowen, Phuong Nguyen, Janet Finer-Moore, Robert M. Stroud 1659-Pos Board B117 DRUG-BINDING TO DISTINCT SITES OF THE MULTIDRUG EXPORTER P- GLYCOPROTEIN. Nghi Tran , Ina Urbatsch, Douglas J. Swartz, Anukriti Singh, Courtney Katz, Benjamin T. Jackson, JoachimWeber 1660-Pos Board B118 Travel Award Winner MOLECULAR MECHANISM FOR STABILIZATION OF VOLTAGE SENSOR AC - TIVE STATE IN PROTON CHANNEL ( CI HV1). Miguel Fernández , Juan J. Al - vear, Emerson M. Carmona, Christian A. Carrillo-Soto, Hans Larsson, Alan Neely, Osvaldo Alvarez, Ramon Latorre, Jose Garate, Carlos L. Gonzalez 1661-Pos Board B119 COLICIN E1 BINDS TO TOLC AS AN OPEN HINGE TO PENETRATE THE OUTER-MEMBRANE. Jimmy Budiardjo

1662-Pos Board B120 STRATEGIES FOR SINGLE-PARTICLE CRYO-ELECTRON MICROSCOPY STUDIES OF SMALL INTEGRAL MEMBRANE PROTEINS. Vikas Navratna , Shyamal Mosalaganti 1663-Pos Board B121 CRYO-EM OF MEMBRANE PROTEINS: WHAT HAVE WE LEARNED IN THE LAST DECADE AND WHAT ARE THE CURRENT CHALLENGES? Doreen Matthies 1664-Pos Board B122 Travel Award Winner CRYOEM ANALYSIS OF GATING DYNAMICS IN MAMMALIAN BESTRO - PHINS. Aaron P. Owji , Alec Kittredge, Yu Zhang, Tingting Yang, Wayne A. Hendrickson Enzyme Function, Cofactors, and Post-translational Modifications (Boards B123 - B147) 1665-Pos Board B123 CONNECTING RAPID PROMOTING VIBRATIONS TO CONFORMATIONAL TRANSITIONS IN HUMAN PURINE NUCLEOSIDE PHOSPHORYLASE. Clara F. Frost , Dimitris Antoniou, Steven D. Schwartz 1666-Pos Board B124 SARS-COV-2 SPIKE BINDING TO ACE2 IS STRONGER AND LONGER RANGED WITH GLYCANS. Yihan Huang, Bradley Harris, Shiaki Minami, Seongwon Jung, Priya Shah, Somen Nandi, Karen McDonald, Roland Faller 1667-Pos Board B125 SUBSTRATE PROMISCUITY - A CONTINUUM FEATURE OF ENZYMES. Deeksha Thakur , Shashi B. Pandit 1668-Pos Board B126 INVESTIGATING THE ROLE OF CONFORMATIONAL DYNAMICS IN PHOS - PHOLIPASE CB FUNCTION. Igi Vilza 1669-Pos Board B127 RIBOSOME-AMPLIFIED METABOLISM, RAMBO, MEASURED BY NMR SPECTROSCOPY. Jianchao Yu , Lisa M. Ramirez, Aaron Premo, Devin B. Busch, Qishan Lin, David S. Burz, Alexander Shekhtman 1670-Pos Board B128 THE EXPANDING WORLD OF METABOLIC ENZYMES MOONLIGHTING AS RNA BINDING PROTEINS. Constance Jeffery , Nicole Curtis, Jay Garg, Cesar Siete, Victoria Ogunniyi, Krupa Patel 1671-Pos Board B129 AN INVESTIGATION OF HISTONES AS A POSSIBLE SUBSTRATE OF CULLIN5- RING LIGASE MEDIATED UBIQUITINATION. Nathan H. Lee , Calvin Lin, Elizabeth A. Komives 1672-Pos Board B130 UBIQUITYLATION OF HISTONES BY CULLIN-RING LIGASES. Calvin P. Lin , Nathan H. Lee, Elizabeth A. Komives 1673-Pos Board B131 DEVELOpmENT OF A SINGLE-MOLECULE APPROACH TO OBSERVE UBIQUITINATION DYNAMICS IN DEFINED CHROMATIN STATES. Alexandra Teslenko , Beat Fierz 1674-Pos Board B132 ELUCIDATING THE EFFECT OF PHOSPHORYLATION ON MOTIF A DEPEN - DENT ACTIVATION OF SIRT1. Addison Chen , Ningkun Wang

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