Biophysical Society 66th Annual Meeting Program Guide

1688-Pos Board B146 EFFECT OF GLYCEROL PATHWAY ON CHOLESTEROL DEGRADATION IN A MYCOBACTERIUM MODEL STRAIN. Jinpeng Yu , Shikui Song, Xiyao Cheng, Meng Gao, Yongqi Huang, Zhengding Su 1689-Pos Board B147 TARGET BACTERIAL DNA GYRASE FOR NEW ANTIBIOTIC DISCOVERY. Fenfei Leng , Eddy Alfonso, Zifang Deng, Daniel Boaretto Protein Aggregates (Boards B148 - B179) 1690-Pos Board B148 AMYLIN PERTURBS THE ORGANISATION OF COLLAGEN NETWORK. MD Asrafuddoza Hazari , Shamik Sen, Ashutosh Kumar 1691-Pos Board B149 Travel Award Winner ELONGATION AND EXPANSION MECHANISM OF LENS CHAPERONE Α-CRYSTALLINS IN DETERRING LIGHT-SCATTERING AGGREGATION. Adam P. Miller , Susan E. O'Neill, Kirsten Lampi, Steve L. Reichow 1692-Pos Board B150 Travel Award Winner AMYLOID FIBRILS FROM FRONTOTEMPORAL LOBAR DEGENERATION WITH TDP-43 INCLUSIONS (FTLD-TDP) ARE COMPOSED OF TMEM106B, RATHER THAN TDP-43. Yi Xiao Jiang , Qin Cao, Michael R. Sawaya, Ro - many Abskharon, Peng Ge, Michael DeTure, Dennis W. Dickson, David S. Board B151 DISRUPTION OF A CONSERVED N-TERMINAL IXI MOTIF OF ΑB-CRYSTALLIN LEADS TO THE FORMATION OF DYNAMIC FIBRILLAR AGGREGATES. Russell McFarland , Steve L. Reichow 1694-Pos Board B152 SUPERRESOLUTION IMAGING OF TAU AGGREGATE CLEARANCE VIA AU - TOPHAGY AND PROTEASOME PATHWAYS. Melina Theoni Gyparaki , Arian Arab, Melike Lakadamyali 1695-Pos Board B153 COMPUTATIONAL STUDY OF INHIBITORY MECHANISMS FOR JANUS IRON OXIDE NANOPARTICLES ON AMYLOID AGGREGATIONS. Zhiyuan Song , Board B154 MODULATORS OF THE PLASMA MEMBRANE PROTECT CELLS FROM DIVERSE TOXIC AGENTS, RANGING FROM PROTEIN MISFOLDED OLIGO - MERS TO PORE FORMING AGENTS. Ryan Limbocker , Ryan P. Kreiser, Liam R. Sasser, Aidan K. Wright, Dillon J. Rinauro, Michele Vendruscolo 1697-Pos Board B155 SINGLE-MOLECULE ANALYSIS OF SOLUBLE IAPP OLIGOMERS AT DIVERSE MEMBRANE SURFACES. Bryan A. Bogin , Zachary Levine 1698-Pos Board B156 SEQUENCE-BASED PREDICTION AND MEASUREMENT OF PH-DEPENDENT PROTEIN SOLUBILITY. Marc Oeller , Pietro Sormanni, Michele Vendruscolo 1699-Pos Board B157 PEPTOIDS AS POTENTIAL MODULATORS TO REDUCE S100B- INDUCED RAGE ACTIVATION IN ALZHEIMER'S DISEASE. Mihyun L. Waugh 1700-Pos Board B158 MECHANISM OF TAU R3 AGGREGATION AND INHIBITION REVEALED BY NMR-BASED CHEMICAL KINETICS. Virginia Casablancas-Antras , Sylvain Demanze, Gary Sharman, Caroline Kerridge, Suchira Bose, Andrew J. Baldwin Eisenberg 1693-Pos Feng Ding 1696-Pos

1675-Pos Board B133 MECHANISTIC INSIGHT INTO IMPACT OF PHOSPHORYLATION ON DY - NAMICS OF FARNESYLTRANSFERASE: TARGETING THE PROTEIN UNDER HYPERINSULINEMIA. Hanife Pekel , Mustafa Guzel, Ozge Sensoy 1676-Pos Board B134 TRADEOFFS OF ELECTROSTATICS AND CHEMICAL POSITIONING IN THE EVOLUTION OF ANTIBIOTIC RESISTANCE IN TEM BETA-LACTAMASES. Steven G. Boxer , Samuel H. Schneider, Jacek A. Kozuch 1677-Pos Board B135 EXPLORING THE NOVEL MECHANISTIC ASPECTS OF FUNCTION OF A HYPERTHERMOPHILE TWO-SITE EXO-AMYLASE-CUM-GLUCANOTRANS - FERASE DISPLAYING SUBSTRATE VERSATILITY. Arpita Sarkar , Pallavi Kaila Sharma, Purnananda Guptasarma 1678-Pos Board B136 EXPLORING THE BASIS FOR SUBSTRATE-DEPENDENT CONTROL OF [4FE4S] REDOX PROPERTIES IN HUMAN DNA PRIMASE. Courtney M. Petersen , Hongxin Wang, Simon J. George, Yoshitaka Yoda, Nobutomo Nagasawa, Hiroaki Matsuura, Stephen P. Cramer, Matthew K. Thompson 1679-Pos Board B137 THEORETICALLY AIDED DESIGN OF THE NITRILE HYDRATASE’S CATALYTIC PROPERTIES - BIOTECHNOLOGICALLY IMPORTANT METALLOENZYME WITH POSTTRANSLATIONAL MODIFICATIONS. Lukasz Peplowski 1680-Pos Board B138 FURTHER INVESTIGATION OF THE INVOLVEMENT OF F0F1 ATPASE AND PRUNE IN THE HYDROLYSIS OF INORGANIC POLYPHOSPHATE (POLYP). Ernest Scoma 1681-Pos Board B139 Travel Award Winner C2 DOMAIN LYSINE CLUSTERS ARE HIGHLY SUSCEPTIBLE TO NON-ENZY - MATIC POST-TRANSLATIONAL MODIFICATIONS. Cisloynny C. Beauchamp- Perez , P. Naomie Kabre, Colin T. Shearn, Jefferson Knight 1682-Pos Board B140 INTERACTION OF MYRISTIC ACID WITH THE HEXACOORDINATE GLOBIN PROTEIN GLOBINX. Jonathan Cedeno-Lugo 1683-Pos Board B141 PHOTOREGULATION OF SMALL G-PROTEIN RAS BY THE MODIFICATION AT HVR USING AZOBENZENE DERIVATIVES. Rufiat Nahar , Md Noor A Alam, IslamMd Alrazi, Kazunori Kondo, Shinsaku Maruta 1684-Pos Board B142 SYNERGISTIC ACTION OF DIFFERENT THERMOSTABLE ESTERASES IN PET DEGRADATION: IMPROVEMENT OF ACTIVITY AGAINST INTERMEDIATE DEGRADATION PRODUCTS BY PROTEIN ENGINEERING. Arpita Mrigwani , Bhishem Thakur, Harman Kaur, Purnananda Guptasarma 1685-Pos Board B143 EXPLORING THE ACTIVITY AND INHIBITION OF UROKINASE-TYPE PLAS - MINOGEN ACTIVATOR (UPA). Harriet J. Song , Constanza Torres-Paris, Elizabeth A. Komives 1686-Pos Board B144 FACTOR XIII CROSSLINKING IN FIBRINOGEN ΑC(233-425) IS ASSISTED BY ELECTROSTATIC AND HYDROPHOBIC RESIDUES IN ΑC(389-403). Francis Dean O. Ablan, Muriel C. Maurer 1687-Pos Board B145 CONNECTING GLUTAMINE SYNTHETASE BIOPHYSICS TO THE CELLULAR ENVIRONMENT. Eric R. Greene , Erin Thompson, D. John Lee, Angelika Arada, Daphne Chen, James Fraser

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