Biophysical Society 66th Annual Meeting Program Guide

1701-Pos Board B159 STRUCTURE OF A PATHOGENIC AMYLOID NUCLEUS DETERMINED BY RA - TIONAL GENETIC DECONSTRUCTION OF AN INTRACELLULAR NUCLEATION BARRIER. Randal Halfmann 1702-Pos Board B160 UNIVERSAL LAB-ON-A-CHIP MICROFLUIDIC SPRAY DEPOSITION FOR BULK AND SINGLE-MOLECULE ANALYTICAL METHODS ON SURFACES. Alyssa M. Miller , Sean K.R. Chia, Tuuli Hakala, Zenon Toprakcioglu, Michele Vendruscolo, Francesco Simone Ruggeri, Tuomas P.J. Knowles 1703-Pos Board B161 BREAKAGE DEPENDENT AMYLOID GROWTH KINETICS : A COMPUTATION - AL STUDY. Jennifer Joseph , Samir K Maji, Ranjith Padinhateeri 1704-Pos Board B162 CONCENTRATION EFFECTS OF POLYCATIONIC POLYMERS ON AMYLOID- BETA AGGREGATION. Suhas Gotla , Silvina Matysiak 1705-Pos Board B163 COUNTERACTION OF AMYLOID-Β AGGREGATION BY VITAMIN A AND E METABOLITES IN A CROWDED ENVIRONMENT. Priyanka Joshi , Sean Chia, Xiaoting Yang, Michele Perni, Johnny Habchi, Michele Vendruscolo 1706-Pos Board B164 ASSESSMENT OF PHYSIOLOGICAL ENVIRONMENT ON NEURODEGENERA - TIVE PEPTIDE AGGREGATION. Abhilash Sahoo , Silvina Matysiak 1707-Pos Board B165 EFFECTS OS SMALL MOLECULE INHIBITORS ON MEMBRANE-DEPENDENT AMYLOID AGGREGATION OF THE BAX C-TERMINAL PEPTIDE. Katherine E. Helme , David A. Price, Poornima Wedamulla, Sean D. Moran 1708-Pos Board B166 PREFERENTIAL INHIBITION OF AMYLOID-BETA OLIGOMERS IDENTIFIED BY SINGLE-MOLECULE STEPWISE PHOTOBLEACHING. Rehana Patel, Emma E. Tadeo, Lara G. Dresser, Mark C. Leake, Steven D. Quinn 1709-Pos Board B167 ISOLATION OF A TAU BINDING PEPTIDE BY PHAGE DISPLAY. Xianlong Huang , Zhiwen Zheng, Yixin Wu, Zhengding Su, Yongqi Huang 1710-Pos Board B168 ATTENUATING THE TOXICITY OF PROTEIN MISFOLDED OLIGOMERS USING AMINOSTEROLS. Liam R. Sasser , Aidan K. Wright, Ryan P. Kreiser, Lam Nguyen, Ryan Limbocker 1711-Pos Board B169 IDENTIFICATION OF ENDOGENOUS AMYLOID-LIKE BODIES IN THE CNS OF DORYTEUTHIS PEALEII. Jaqulin N. Wallace , Catherine L.A. Chang, Yuto Kegawa, Emily Feigen, Amelia J. Ralowicz, Glen W. Humphrey, Jennifer D. Petersen, Paul S. Blank, Joshua Zimmerberg 1712-Pos Board B170 SIMULTANEOUS FRACTIONATION AND CHARACTERISATION OF PRE-FI - BRILLAR AGGREGATES IN SOLUTION WITH SINGLE-MOLECULE MICRO - FLUIDICS. Ewa A. Andrzejewska , Georg Krainer, Catherine K Xu, Raphaël Jacquat, Matthias M. Schneider, William Arter, Tuomas P.J. Knowles 1713-Pos Board B171 SORTASE A-MEDIATED SITE-SPECIFIC LABELING OF TAU PROTEIN. Yuanjie Li , Saurabh Awasthi, Louise Bryan, Peter N. Nirmalraj, Michael Mayer 1714-Pos Board B172 UNRAVELLING THE KINETICS OF Α-SYNUCLEIN AGGREGATION VIA THE CONDENSATION PATHWAY. Samuel T. Dada 1715-Pos Board B173 Travel Award Winner IDENTIFYING AND CHARACTERIZING EFFECTORS OF LOW COMPLEXITY PROTEIN DOMAIN ASSEMBLY. Khaled M. Jami , John C. Voss, Dylan T. Murray

1716-Pos Travel Award Winner STRUCTURE DETERMINATION OF AGED LIQUID DROPLETS OF THE NEU - RODEGENERATION-ASSOCIATED TAR-DNA BINDING PROTEIN-43. Blake Board B175 DIVALENT CATIONS INFLUENCE HTT AGGREGATION BUT ONLY IN THE PRESENCE OF LIPID MEMBRANES. Adam Skeens , Justin A. Legleiter 1718-Pos Board B176 Travel Award Winner KINETIC ANALYSIS OF TAU AGGREGATION FOR DRUG DISCOVERY. Dillon J. Rinauro , Michele Vendruscolo 1719-Pos Board B177 MONOMER RECRUITMENT BY Α-SYNUCLEIN FIBRILS RELIES ON MONO - MER N-TERMINAL INTERACTION. Bridget Milorey , Jonathan Stoeber, Cody Hoop, Jean Baum 1720-Pos Board B178 EFFECT OF POINT MUTATIONS ON THE NETWORK OF SIDE CHAIN IN - TERACTIONS OF PRION PROTEIN FIBRILS WITH DISTINCT QUATERNARY STRUCTURES. Steffany D. Nguyen , Danielle Hotalling, Linh Bui, Patricia Soto 1721-Pos Board B179 HUMAN AQUAPORIN-4 ORTHOGONAL ARRAY OF PARTICLES IN BIOMI - METIC MEMBRANES: AGGREGATION, PROTEIN TRACKING AND STED. Jessica D. Carder , Barbara Barile, Grazia Paola Nicchia, James A. Brozik Liquid-Liquid Phase Separation I (Boards B180 - B200) 1722-Pos Board B180 PHYSICAL DESCRIPTIONS OF MOLECULAR AND MESOSCALE ORGANIZA - TIONS OF PROTEINS WITHIN CONDENSATES AND AT INTERFACES. Mina Farag , Rohit V. Pappu 1723-Pos Board B181 A PROGRAMMABLE LANDSCAPE OF VISCOELASTIC PROTEIN-RNA CON - DENSATES. Ibraheem Alshareedah , Priya R. Banerjee 1724-Pos Board B182 SARS-COV-2 NUCLEOCAPSID PROTEIN FORMS CONDENSATES WITH VIRAL GENOMIC RNA. Amanda Jack , Luke Ferro, Michael J. Trnka, Eddie Wehri, Amrut Nadgir, Xammy Nguyenla, Douglas Fox, Katelyn Costa, Sarah Stan - ley, Julia Schaletzky, Ahmet Yildiz 1725-Pos Board B183 BETA-STRAND MEDIATED BIOLOGICAL CONDENSATION MECHA - NISMS. Dylan T. Murray , Yuuki F. Wittmer, Blake D. Fonda, Khaled M. Jami, Estely Carranza 1726-Pos Board B184 HELICAL REGION NEAR POLY-Q TRACT IN PRION-LIKE DOMAIN OF ARABI - DOPSIS ELF3 PLAYS ROLE IN TEMPERATURE-SENSING MECHANISM. Richard J. Lindsay , Lukas S. Stelzl, Lisa Pietrek, Gerhard Hummer, Philip A. Wigge, Sonya M. Hanson 1727-Pos Board B185 LIGHT-CONTROLLED 3D GENOME REORGANIZATION THROUGH CAPIL - LARY FORCES. Yoonji Kim , Amy R. Strom, Clifford P. Brangwynne 1728-Pos Board B186 UNDERSTANDING THE MECHANISM OF TCF3-HLF FUSION ONCOPRO - TEIN-DRIVEN LEUKEMOGENESIS. Hazheen K. Shirnekhi , Scott D. Gorman, Nicole L. Michmerhuizen, Swarnendu Tripathi, Anna Medyukhina, Khaled A. Khairy, Charles G. Mullighan, Richard W. Kriwacki Board B174 D. Fonda 1717-Pos

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