Biophysical Society 66th Annual Meeting Program Guide

1871-Pos Board B329 SYSTEMATIC ANALYSES OF STRUCTURE/FUNCTION VARIABILITY OF VIRAL K + CHANNELS FOR THE DEVELOpmENT OF SYNTHETIC CHANNELS. Kerri Kukovetz , Matea Cortolano, Jonas Stein, Oliver Rauh, Alessandro Porro, Anna Moroni, Gerhard Thiel 1872-Pos Board B330 A GLYCOLYTIC ENZYME COMPLEX AND CREATINE KINASE LOCALLY AND DIFFERENTIALLY REGULATE ATP-SENSITIVE POTASSIUM (K ATP ) CHAN - NELS IN PANCREATIC ISLET ALPHA AND BETA CELLS. Thuong Ho , Evgeniy Potapenko, Matthew J. Merrins 1873-Pos Board B331 IDENTIFICATION OF A DISTINCT LOCK SYSTEM FOR CAMP BINDING IN HCN CHANNELS. Andrea Saponaro , Alessandro Porro, Jana Kusch, Uta Enke, Klaus Benndorf, Gerhard Thiel, Anna Moroni 1874-Pos Board B332 HOW DOES THE LOCAL ENVIRONMENT ALTER THE MECHANISM OF TWO LIGAND-GATED ION CHANNELS: OOCYTES VS HEKS. Susanne M. Mesoy , Sarah C. Lummis 1875-Pos Board B333 SARS-COV-2 S1 SPIKE PROTEIN PEPTIDES INHIBIT ALPHA 7 NACHRS AND ARE COUNTERACTED BY A PAM AT ALPHA 7. Joseph Farley , Jonathan B. Travel Award Winner STRUCTURE AND PROPERTIES OF THE SELECTIVITY FILTER OF HOMO- AND HETERO- TETRAMERES OF PLANT IONOTROPIC GLUTAMATE RECEP - TORS: A MODELLING APPROACH. Carlos Navarro , Holger Gohlke, Jose A. Feijo, Erwan Michard 1877-Pos Board B335 S-ACYLATION REGULATES STORE-OPERATED CALCIUM ENTRY. Savannah J. West , Goutham Kodakandla, Qiaochu Wang, Ritika Tewari, Michael X. Zhu, Darren Boehning, Askar M. Akimzhanov 1878-Pos Board B336 LIPID DIRECTIVE EPITHELIAL SECRETION BY ER-pm TETHERS. Paramita Sarkar , Benjamin Luscher, Zengyou Ye, Malini Ahuja, Shmuel Muallem 1879-Pos Board B337 DIVALENT CATIONS PROMOTE PANX1 CHANNEL ACTIVITY THROUGH ITS C-TERMINAL DOMAIN. Erik K. Henze , Toshimitsu Kawate 1880-Pos Board B338 TACAN/TMEM120A INHIBITS MECHANICALLY ACTIVATED PIEZO2 CHAN - NELS. Matthew Gabrielle , John Del Rosario, Yevgen Yudin, Tibor Rohacs 1881-Pos Board B339 EFFECT OF ELECTROSTATIC INTERACTIONS IN THE VOLTAGE-INDUCED CLOSURE OF BETA-BARREL CHANNELS: INSIGHTS FROM ELECTROPHYSI - OLOGY EXPERIMENTS AND THEORETICAL CALCULATIONS. Deborah Aurora Perini , Laidy M. Alvero-González, Maria Lidon Lopez-Peris, Anto - nio Alcaraz, Maria Queralt-Martin 1882-Pos Board B340 HYDROPHOBIC DEWETTING IN ION CHANNEL-LIKE NANOPORES. Samantha Schultz , Erik Nordquist, Jianhan Chen 1883-Pos Board B341 ION CONDUCTION MECHANISM AS A FINGERPRINT OF POTASSIUM CHANNELS. Saul Gonzalez-Resines , Carmen Domene, Simone Furini, Matteo Masetti, Riccardo Ocello Anderson 1876-Pos Board B334

1858-Pos Board B316 DIAZEPAM BINDING INHIBITOR POSITIVELY MODULATES Α5Β3 GABA-A RECEPTORS. Jennifer S. Borchardt , Robert A. Pearce, Cynthia Czajkowski 1859-Pos Board B317 ROLE OF CYTOPLASMIC CAP IN DETERMINING THE ION SELECTIVITY OF P2X RECEPTOR CHANNELS. Stephanie W. Tam , Mufeng Li, Kenton Swartz 1860-Pos Board B318 INFLUENCE OF INCUBATION PARAMETERS ON SURVIVABILITY AND FUNC - TIONALITY OF XENOPUS LAEVIS OOCYTES. Nils Otten , Michael Hollmann, Horst Lohmann 1861-Pos Board B319 HOW DOES THE 5-HT 3 RECEPTOR MX HELIX MODULATE FUNC - TION? James H. Mocatta, Susanne M. Mesoy, Sarah C. Lummis 1862-Pos Board B320 APETX2 BINDS TO A DISTAL SITE ON ASIC3 VIA A PROLINE-RICH RE - GION. Kyle D. Berger , David M. MacLean 1863-Pos Board B321 DESENSITIZATION AND CHANNEL CONDUCTANCE OF THE GABA TYPE A RECEPTORS DEPENDS ON ELECTROSTATIC INTERACTIONS IN THE TOP PART OF THE ION PORE. Michal A. Michalowski , Katarzyna Terejko, Mi - chalina Gos, Marta M. Czyżewska, Jerzy W. Mozrzymas 1864-Pos Board B322 STUDYING ALLOSTERIC CONFORMATIONAL TRANSITION IN GLYCINE RECEPTORS THROUGH PROTEIN PERTURBATION METHOD. Farzaneh Travel Award Winner SINGLE-MOLECULE BINDING DYNAMICS AND COOPERATIVITY OF THE FIRST TWO CYCLIC NUCLEOTIDES AT THE TAX-4 CNG CHANNEL. Vishal R. Patel , Arturo M. Salinas, Darong Qi, Shipra Gupta, David J. Sidote, Marcel P. Goldschen-Ohm 1866-Pos Board B324 REFER ANALYSIS OF Α 1 Β 2 Γ 2 GABA TYPE A RECEPTOR SUGGESTS A SLIGHT PHASE SHIFT BETWEEN PRINCIPAL AND COMPLEMENTARY SUBUNITS AT THE EXTRACELLULAR DOMAIN UPON CHANNEL ACTIVATION. Jerzy W. Mozrzymas , Michal A. Michalowski, Katarzyna Terejko, Marek Brodzki, Przemyslaw Kaczor 1867-Pos Board B325 HIGH-THROUGHPUT MEASUREMENT OF HUMAN ASIC1A INTRACEL - LULAR DOMAIN ENVIRONMENT USING GENETIC CODE EXPANSION AND SPECTRAL FLOW CYTOMETRY. Tyler A. Couch , David M. MacLean Ion Channel Regulatory Mechanisms (Boards B326 - B341) 1868-Pos Board B326 BIDIRECTIONAL MODULATION OF ION CHANNELS WITH DIVALENT NANOBODIES. Travis J. Morgenstern , Arden Darko-Boateng, Papiya Choudhury, Sri Karthika Shanmugam, Xinle Zou, Henry M. Colecraft 1869-Pos Board B327 DISTINCTIVE REGULATION OF CA V 3.1 AND CA V 3.2 LOW-VOLTAGE-AC - TIVATED CALCIUM CHANNELS BY NEDD4 FAMILY E3 UBIQUITIN LIGAS - ES. Arden Darko-Boateng , Henry M. Colecraft 1870-Pos Board B328 CHARACTERIZATION OF ENDOGENOUS KV1.3 CHANNEL ISOFORMS IN T CELLS. Julia Serna, Sara Moreno-Estar, Diego A. Peraza, Dino Gobelli, Maria Simarro, José R. López López, Pilar Cidad, Miguel A. de la Fuente, M. Teresa Perez-Garcia Jalalypour 1865-Pos Board B323

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