Biophysical Society 66th Annual Meeting Program Guide

Ion Channels, Pharmacology, and Disease I (Boards B342 - B356) 1884-Pos Board B342 DEVELOpmENT OF I KATP ION CHANNEL BLOCKERS TARGETING SULFONYL - UREA RESITANT MUTANT KIR6.2 BASED CHANNELS FOR TREATING DEND SYNDROME. Theres Friesacher , Marien J.C. Houtman, Xingyu Chen, Marcel van der Heyden, Anna Stary-Weinzinger 1885-Pos Board B343 RAPID CHARACTERIZATION OF THE FUNCTIONAL AND PHARMACOLOGI - CAL CONSEQUENCES OF CANTU SYNDROME KATP CHANNEL MUTA - TIONS IN INTACT CELLS. Jian Gao , Colin G. Nichols 1886-Pos Board B344 POSITIVE MODULATION OF SK CHANNELS BY CYPPA DEPENDS ON THE HA/HB HELICES. Young Woo Nam , Meng Cui, Razan Orfali, Mohammad A. Rahman, Grace Yang, Miao Zhang 1887-Pos Board B345 HALOPERIDOL BLOCKS BK CHANNELS BY A "FOOT IN THE DOOR" MECHANISM. Alexandre G. Vouga , Brad S. Rothberg 1888-Pos Board B346 Travel Award Winner BK CA CHANNELS IN EXOSOMES REGULATE THEIR CARGO AND FUNC - TION. Shridhar K. Sanghvi , Julie Dougherty, Divya Sridharan, Devasena Ponnalagu, Mayukha Dyta, Parker Evans, Vishnu Sundaresan, Mahmood Khan, Harpreet Singh 1889-Pos Board B347 CHARACTERIZATION OF DROSOPHILA MELANOGASTER SLO1 CHANNEL USING MUTAGENESIS AND AUTOMATED PATCH CLAMP MEASURE - MENTS ON SYNCROPATCH384 (NANION TECHNOLOGIES). Andreas Brockmann , Ulrich Ebbinghaus-Kintscher 1890-Pos Board B348 A NOVEL PEPTIDE FROM THE VENOM OF C. MARGARITATUS HAS UNIQUE PRIMARY STRUCTURE AND INHIBITS KV1.2 AND KV1.3 WITH HIGH AFFINITY. Muhammad Umair Naseem , José Beltrán-Vidal, Edson Carcamo-Noriega, Lourival D. Possani, Gyorgy Panyi 1891-Pos Board B349 Travel Award Winner MULTIGENIC, DOMINANT-NEGATIVE LOSS-OF-FUNCTION CAUSED BY AN EPILEPSY-ASSOCIATED MUTATION IN K V 1.2 ( KCNA2 ). Michelle Nilsson , Sarah H. Lindström, Maki Kaneko, Kaiqian Wang, Teresa Minguez Vinas, Marina Angelini, Federica Steccanella, Deborah Holder, Michela Ottolia, Riccardo Olcese, Antonios Pantazis 1892-Pos Board B350 DEVELOpmENT OF A QPATCH CURRENT-CLAMP ASSAY AS A PHYSIOLOGI - CALLY RELEVANT SCREEN FOR KV1.3 INHIBITORS. Stefano Stabilini, Alexandre J. Loucif, Nicola Secomandi, Edward B. Stevens 1893-Pos Board B351 K V 1.3 CHANNEL INHIBITION BY INDOLIC COMPOUNDS. María Baena Nuevo , Alba Vera Zambrano, Carolina Martinez-Laperche, Cecilia Muñoz- Calleja, Ismael Buño, Juan Manuel Zapata, Gema Perez-Chacon, Teresa Gonzalez Gallego 1894-Pos Board B352 MODULATION OF K V 1.5 CHANNEL EXPRESSION AND FUNCTION BY THE SIGMA 1 RECEPTOR. Alba Vera Zambrano , Susanne Rinné, Maria Baena-Nuevo, Daniel Morales-Cano, Bianca Barreira, Niels Decher, Angel Cogolludo, Teresa Gonzalez Gallego

1895-Pos Board B353 TWO UNCHARACTERIZED POINT MUTATIONS IN THE CARDIAC KV7.1 CHANNEL INFLUENCE ITS CONDUCTANCE AND LEAD TO LQTS IN THE PA - TIENT. Julia Kacher , Maria Karlova, Grigory Gluhov, Denis Abramochkin ⁠ , Elena Zaklyazminskaya, Olga Sokolova 1896-Pos Board B354 CANNABIDIOL DIFFERENTIALLY MODULATES KV7 CHANNELOPATHY- RELATED PHENOTYPES. Michael Pökl , Veronika Linhart, Irene Hiniesto Iñigo, Sara I. Liin 1897-Pos Board B355 PREDICTING ARRHYTHMOGENICITY: STRUCTURAL MODELING OF SAFE AND UNSAFE HERG BLOCKERS USING ROSETTA. Aiyana Emigh Cortez , Kevin DeMarco, Kazuharu Furutani, Jon T. Sack, Colleen E. Clancy, Igor V. Vorobyov, Vladimir Yarov-Yarovoy 1898-Pos Board B356 INTERFACING A REAL-TIME DYNAMIC CLAMP SYSTEMWITH NEURON SIMULATION SOFTWARE IN LIVING CELLS. Mark W. Nowak , Leigh Korbel, Alex Kane, Brian K. Panama, Michael Hines, Nicholas T. Carnevale, Glenna C.L. Bett, Randall L. Rasmusson Membrane Pumps, Transporters, and Exchangers II (Boards B357 - B370) 1899-Pos Board B357 DYNAMIC REGULATION OF SERCA BY PHOSPHOLAMBAN AND DWORF. Sean R. Cleary , Xuan Fang, Ellen E. Cho, Marsha P. Pribadi, Jaro - slava Seflova, Jordan R. Beach, Peter M. Kekenes-Huskey, Seth L. Robia 1900-Pos Board B358 SEQUESTRATION OF MEMBRANE MICROPEPTIDES IN HETERO-OLIGO - MERS DECREASES THEIR REGULATORY INTERACTION WITH THE SERCA CALCIUM PUMP. Taylor A. Phillips , Garrett Hauck, Marsha P. Pribadi, Ellen E. Cho, Sean R. Cleary, Seth L. Robia 1901-Pos Board B359 CALCULATING NHTMEM16 LIPID SCRAMBLING RATES USING WEIGHTED ENSEMBLE. Christina A. Stephens , Neville Bethel, Michael Grabe 1902-Pos Board B360 UNDERSTANDING THE MECHANISM OF LIPID TRANSPORT THROUGH THE MLA SYSTEM IN E. COLI . Dhenesh Puvanendran , Mark MacRae, Max Haase, Gira Bhabha, Damian C. Ekiert 1903-Pos Board B361 ELUCIDATING BACTERIAL LIPID TRANSPORT MECHANISMS BY THE EN - VELOPE SPANNING LETAB COMPLEX. Cristina C. Santarossa , Minkyung Baek, Gira Bhabha, Damian Ekiert 1904-Pos Board B362 DIRECT OBSERVATION OF REGULATION BY MODE-SWITCHING OF A MAMMALIAN BRAIN V-ATPASE. Eleftherios I. Kosmidis 1905-Pos Board B363 USING ANGLE-DEPENDENT VELOCITY TO DETECT FAST STATES IN ROTARY MOTORS. Sandor Volkan-Kacso 1906-Pos Board B364 THE SUBSTRATE SPECIFICITY OF THE SMALL MULTIDRUG RESISTANCE FAMLY. Olive E. Burata , Randy Stockbridge 1907-Pos Board B365 BIOPHYSICAL CHARACTERIZATION OF SMALL MULTIDRUG RESISTANCE (SMR) TRANSPORTER, GDX-CLO. Trevor J. Yeh , Randy Stockbridge

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